scholarly journals Short- and long-term surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis: Relationships with neuropathology

Epilepsia ◽  
2015 ◽  
Vol 57 (2) ◽  
pp. 306-315 ◽  
Author(s):  
Francesco Deleo ◽  
Rita Garbelli ◽  
Gloria Milesi ◽  
Francesca Gozzo ◽  
Manuela Bramerio ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Surgical Outcomes ◽  
Hippocampal Sclerosis ◽  
Short And Long Term

scholarly journals Long-term surgical outcomes of temporal lobe epilepsy associated with low-grade brain tumors

Cancer ◽  
2009 ◽  
Vol 115 (24) ◽  
pp. 5771-5779 ◽  
Author(s):  
Ji Hoon Phi ◽  
Seung-Ki Kim ◽  
Byung-Kyu Cho ◽  
Seo Young Lee ◽  
Su Yeon Park ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Surgical Outcomes ◽  
Low Grade

Predictive factors of long-term outcomes of surgery for mesial temporal lobe epilepsy associated with hippocampal sclerosis

Epilepsia ◽  
2017 ◽  
Vol 58 (8) ◽  
pp. 1473-1485 ◽  
Author(s):  
Bertrand Mathon ◽  
Franck Bielle ◽  
Séverine Samson ◽  
Odile Plaisant ◽  
Sophie Dupont ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Predictive Factors ◽  
Hippocampal Sclerosis ◽  
Mesial Temporal Lobe Epilepsy ◽  
Long Term Outcomes ◽  
Mesial Temporal Lobe

scholarly journals Intrinsic Thalamic Network in Temporal Lobe Epilepsy With Hippocampal Sclerosis According to Surgical Outcomes

2021 ◽  
Vol 12 ◽  
Author(s):  
Kyoo Ho Cho ◽  
Ho-Joon Lee ◽  
Kyoung Heo ◽  
Sung Eun Kim ◽  
Dong Ah Lee ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Surgical Outcomes ◽  
Hippocampal Sclerosis ◽  
Three Dimensional ◽  
Thalamic Nuclei ◽  
Characteristic Path Length ◽  
Ipsilateral Hemisphere ◽  
Hippocampal Subfields ◽  
Significant Difference

Background: The aim of this study was to identify the differences of intrinsic amygdala, hippocampal, or thalamic networks according to surgical outcomes in temporal lobe epilepsy (TLE) patients with hippocampal sclerosis (HS).Methods: We enrolled 69 pathologically confirmed TLE patients with HS. All patients had pre-operative three-dimensional T1-weighted MRI using a 3.0 T scanner. We obtained the structural volumes of the amygdala nuclei, hippocampal subfields, and thalamic nuclei. Then, we investigated the intrinsic networks based on volumes of these structures using structural covariance and graph theoretical analysis.Results: Of the 69 TLE patients with HS, 21 patients (42.1%) had poor surgical outcomes, whereas 40 patients (57.9%) had good surgical outcomes. The volumes in the amygdala nuclei, hippocampal subfields, and thalamic nuclei were not different according to surgical outcome. In addition, the intrinsic amygdala and hippocampal networks were not different between the patients with poor and good surgical outcomes. However, there was a significant difference in the intrinsic thalamic network in the ipsilateral hemisphere between them. The eccentricity and small-worldness index were significantly increased, whereas the characteristic path length was decreased in the patients with poor surgical outcomes compared to those with good surgical outcomes.Conclusion: We successfully demonstrated significant differences in the intrinsic thalamic network in the ipsilateral hemisphere between TLE patients with HS with poor and good surgical outcomes. This result suggests that the pre-operative intrinsic thalamic network can be related with surgical outcomes in TLE patients with HS.

scholarly journals Very Long-Term Outcome of Non-Surgically Treated Patients with Temporal Lobe Epilepsy with Hippocampal Sclerosis: A Retrospective Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0159464 ◽  
Author(s):  
Tsugiko Kurita ◽  
Kotaro Sakurai ◽  
Youji Takeda ◽  
Toru Horinouchi ◽  
Ichiro Kusumi
Keyword(s):  
Retrospective Study ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Hippocampal Sclerosis ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis

2015 ◽  
Vol 73 (12) ◽  
pp. 1014-1018 ◽  
Author(s):  
Lucas Crociati Meguins ◽  
Rodrigo Antônio Rocha da Cruz Adry ◽  
Sebastião Carlos da Silva Júnior ◽  
Carlos Umberto Pereira ◽  
Jean Gonçalves de Oliveira ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Surgical Outcomes ◽  
Hippocampal Sclerosis ◽  
Class I ◽  
Tertiary Center ◽  
One Year ◽  
Patients With Epilepsy ◽  
Retrospective Investigation

ABSTRACT Objective To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients.

scholarly journals Long-term surgical outcomes in patients with drug-resistant temporal lobe epilepsy and no histological abnormalities

2013 ◽  
Vol 28 (9) ◽  
pp. 543-549
Author(s):  
J.C. Benedetti-Isaac ◽  
M. Torres-Zambrano ◽  
J. Fandiño-Franky ◽  
J. Dussán-Ordóñez ◽  
A. Herrera-Trujillo ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Surgical Outcomes ◽  
Drug Resistant

Hidden Objective Memory Deficits Behind Subjective Memory Complaints in Patients With Temporal Lobe Epilepsy

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000013212
Author(s):  
Béatrice Lemesle ◽  
Emmanuel J. Barbeau ◽  
Emilie Milongo Rigal ◽  
Marie Denuelle ◽  
Luc Valton ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Wide Spectrum ◽  
Hippocampal Sclerosis ◽  
Long Term Memory ◽  
Subjective Memory ◽  
Term Memory ◽  
Memory Tests ◽  
Memory Complaints

Objective:To test the hypothesis that temporal lobe epilepsy (TLE) patients with subjective initial memory complaints (not confirmed by an objective standard assessment) and various phenotypes also show objective very long-term memory deficit with accelerated long-term forgetting. We tested TLE patients with two surprise memory tests after three weeks: the standard Free and Cued Selective Reminding Test (FCSRT), and Epireal, a new test specifically designed to capture more ecological aspects of autobiographical memory.Methods:47 TLE patients (12 hippocampal sclerosis, 12 amygdala enlargement, 11 extensive lesions, 12 normal MRI) who complained about their memory, but for whom the standard neuropsychological assessment did not reveal any memory impairment after a standard delay of 20 minutes, underwent two surprise memory tests after three weeks. They were compared to 35 healthy control subjects.Results:After three weeks, FCSRT and Epireal recall scores were significantly lower in patients than in controls (p<0.001). There was no significant correlation between FCSRT and Epireal scores (p=0.99). Seventy-six percent of TLE patients had objective impairment on at least one of these very long-term memory tests, regardless of the existence and type of lesion or response to antiseizure medication. Easily applicable, Epireal had a higher effect size, detected deficits in 28% more patients, and is a useful addition to the standard workup.Conclusion:Assessing long-term memory should be broadened to a wide spectrum of TLE patients with a memory complaint, regardless of the epileptic syndrome, whether or not associated with a lesion. This could lead to rethinking TLE nosology associated with memory.

Temporopolar blurring in temporal lobe epilepsy with hippocampal sclerosis and long-term prognosis after epilepsy surgery

2015 ◽  
Vol 112 ◽  
pp. 76-83 ◽  
Author(s):  
Pedro V.F. Naves ◽  
Luís Otávio S.F. Caboclo ◽  
Henrique Carrete ◽  
Bruno V. Kelmann ◽  
Larissa B. Gaça ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Epilepsy Surgery ◽  
Hippocampal Sclerosis ◽  
Long Term Prognosis
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