scholarly journals The historical evolution of, and the paradigms shifts in, the therapy of convulsive status epilepticus over the past 150 years

Epilepsia ◽  
2013 ◽  
Vol 54 ◽  
pp. 64-67 ◽  
Author(s):  
Simon Shorvon
Keyword(s):  
Status Epilepticus ◽  
Convulsive Status Epilepticus ◽  
Historical Evolution ◽  
The Past

scholarly journals Emergency management of the paediatric patient with convulsive status epilepticus

2021 ◽  
Vol 26 (1) ◽  
pp. 50-57
Author(s):  
Kyle C McKenzie ◽  
Cecil D Hahn ◽  
Jeremy N Friedman
Keyword(s):  
Clinical Practice ◽  
Status Epilepticus ◽  
Emergency Management ◽  
Treatment Algorithm ◽  
Position Statement ◽  
Convulsive Status Epilepticus ◽  
Pharmacological Management ◽  
The Past ◽  
New Treatment ◽  
New Evidence

Abstract This guideline addresses the emergency management of convulsive status epilepticus (CSE) in children and infants older than 1 month of age. It replaces a previous position statement from 2011, and includes a new treatment algorithm and table of recommended medications based on new evidence and reflecting the evolution of clinical practice over the past several years. This statement emphasizes the importance of timely pharmacological management of CSE, and includes some guidance for diagnostic approach and supportive care.

scholarly journals Advances in the management of generalized convulsive status epilepticus: what have we learned?

Brain ◽  
2021 ◽  
Author(s):  
Aidan Neligan ◽  
Sanjeev Rajakulendran ◽  
Matthew C. Walker
Keyword(s):  
Status Epilepticus ◽  
Case Reports ◽  
Meta Analysis ◽  
Treatment Strategies ◽  
Case Series ◽  
Refractory Status Epilepticus ◽  
Convulsive Status Epilepticus ◽  
The Past ◽  
Class A ◽  
Adults And Children

Abstract Convulsive status epilepticus is the most serious manifestation of an epileptic diathesis. In the early stages (5–30 min), there exists class A evidence to support the efficacy of benzodiazepines as first-line treatment. As status epilepticus progresses into the later stages, the evidence for treatment becomes less robust until we are depending upon short case series and case reports for the treatment of refractory status epilepticus. However, the past year saw the publication of three randomized controlled trials in the setting of benzodiazepine-resistant established convulsive status epilepticus: the EcLiPSE and ConSEPT studies, compared levetiracetam to phenytoin in children; and the ESETT study compared fosphenytoin, levetiracetam and sodium valproate in adults and children. In addition, the emergence of data from the SENSE study, a multicentre multinational prospective cohort study and the publication of a systematic review and meta-analysis of the mortality of status epilepticus over the past 30 years, has brought the treatment of status epilepticus into sharp focus. In this update we provide a detailed analysis of these studies and their impact on clinical practice. We review contentious areas of management in status epilepticus where a consensus is lacking and advance the case for more research on existing and alternative treatment strategies.

A KUHNIAN INTERPRETATION OF THE HISTORICAL EVOLUTION OF ACCOUNTING

1989 ◽  
Vol 16 (2) ◽  
pp. 1-41 ◽  
Author(s):  
Barry E. Cushing
Keyword(s):  
Historical Evolution ◽  
Scientific Revolutions ◽  
The Past ◽  
Structure Of Scientific Revolutions ◽  
Model Following ◽  
Entry Model ◽  
Scientific Disciplines ◽  
Uncertain Future ◽  
Double Entry ◽  
Dominant Paradigm

Distinct parallels exist between the historical evolution of scientific disciplines, as explained in Thomas Kuhn's The Structure of Scientific Revolutions, and the historical evolution of the accounting discipline. These parallels become apparent when accounting's dominant paradigm is interpreted to be the double-entry bookkeeping model. Following this interpretation, the extensive articulation of the double-entry model over the past four centuries may be seen to closely resemble the “normal science” of Kuhn's theory. Further parallels become apparent when Kuhn's concept of the disciplinary crises that precede scientific revolutions is compared to developments in the accounting discipline over the past 25 years. This portrayal of accounting's evolution suggests an uncertain future for the accounting discipline.

Experiences of Knowledge Transfer on Industrial Heritage Using Games, Storytelling, and New Technologies

2021 ◽  
Vol 14 (2) ◽  
pp. 1-26
Author(s):  
Gonzalo Andrés López ◽  
David Checa Cruz
Keyword(s):  
New Technologies ◽  
Daily Life ◽  
3D Modelling ◽  
Historical Evolution ◽  
Educational Tool ◽  
Economic Activities ◽  
Industrial Heritage ◽  
Urban Economic ◽  
The Past ◽  
A Value

The industry has a relevant spatial and socioeconomic importance in most of the Spanish cities and nowadays is one of the main urban economic activities. However, in many situations, and despite recent advances in the past two decades, industrial heritage is a value that is still not sufficiently widespread in society. The factories, their activity, and their historical evolution are often disconnected and isolated from the daily life of the cities, being quite an unknown aspect for most of the citizens. This contribution presents the result of various experiences of knowledge transmission on the heritage value of industry, through the use of games and storytelling technique as an educational tool and the combination of different technologies (3D modelling, videomapping, virtual reality) as useful tools to spread the explanation of this phenomenon.

Salzburg Criteria, A Useful Tool in Non-Convulsive Status Epilepticus Diagnosis: A Retrospective Study

2021 ◽  
pp. 155005942199171
Author(s):  
Adriana Gómez Domínguez ◽  
Raidili C. Mateo Montero ◽  
Alba Díaz Cid ◽  
Antonio J. P. Mazarro ◽  
Ignacio R. Bailly-Bailliere ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Status Epilepticus ◽  
Prospective Studies ◽  
Correct Diagnosis ◽  
Original Description ◽  
Neurological Deficits ◽  
Convulsive Status Epilepticus ◽  
Poor Outcome

Introduction. Non-convulsive status epilepticus (NCSE) has been traditionally a challenging electroencephalographic (EEG) diagnosis. For this reason, Salzburg consensus criteria (SCC) have been proposed to facilitate correct diagnosis. Methods. We retrospectively reanalyzed 41 cases referred to our department (from 2016 to 2018) under the suspicion of NCSE. In this study, we compared the original description (standard criteria) versus the updated description (SCC) of the same EEG. Results. Originally, 15 patients were diagnosed as NCSE (37%) and 26 patients as no NCSE (63%), using the standard criteria. Then, we analyzed EEGs according to the SCC, which led to the following results: 9 patients fulfilled the criteria for definite NCSE (22%), 20 patients were diagnosed as possible NCSE (49%) and 12 patients were diagnosed as no NCSE (29%). Subsequently, when we analyze the outcome of possible NCSE cases, we note that 50% of these patients presented mild-poor outcome (neurological deficits, deceased). Indeed, we observed worse outcomes in patients previously diagnosed as no NCSE and untreated, specifically post-anoxic cases. Conclusions. Salzburg criteria seem to be a useful tool to support NCSE diagnosis, introducing the category of possible NCSE. In our study, we observed that it contributes to improving the prognosis and management of the patients. However, more prospective studies are needed to demonstrate the accuracy of SCC.

Not all patients with convulsive status epilepticus intubated in pre-hospital settings meet the criteria for refractory status epilepticus

Seizure ◽  
2021 ◽  
Vol 88 ◽  
pp. 29-35
Author(s):  
Sinead Zeidan ◽  
Benjamin Rohaut ◽  
Hervé Outin ◽  
Francis Bolgert ◽  
Marion Houot ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Refractory Status Epilepticus ◽  
Convulsive Status Epilepticus ◽  
Refractory Status
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