scholarly journals Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis

2021 ◽  
Author(s):  
Fatme Seval Ismail ◽  
Marianna Spatola ◽  
Friedrich G. Woermann ◽  
Stoyan Popkirov ◽  
Johannes Jungilligens ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Limbic Encephalitis ◽  
Temporal Lobe Seizures ◽  
Autoimmune Limbic Encephalitis

scholarly journals D.05 SREDA-like temporal EEG seizure pattern in LGI1-antibody mediated encephalitis

2016 ◽  
Vol 43 (S2) ◽  
pp. S14-S14
Author(s):  
C Steriade ◽  
S Mirsattari ◽  
BJ Murray ◽  
R Wennberg
Keyword(s):  
Clinical Features ◽  
Temporal Lobe ◽  
Limbic Encephalitis ◽  
Cognitive Symptoms ◽  
Epileptiform Discharges ◽  
Interictal Epileptiform Discharges ◽  
Eeg Abnormalities ◽  
Eeg Data ◽  
Temporal Lobe Seizures ◽  
Eeg Recordings

Background: Leucine-rich glioma inactived-1 (LGI1) antibodies are associated with limbic encephalitis and distinctive seizure types, which are typically immunotherapy-responsive. While nonspecific EEG abnormalities are commonly seen, specific EEG characteristics are not currently understood to be useful for suspecting the clinical diagnosis. Based on initial observations in two patients, we analyzed the EEG recordings in a larger series of patients and describe a novel ictal pattern that can suggest the diagnosis of LGI1-antibody mediated encephalitis, even in the absence of common clinical features. Methods: Clinical and EEG data were collected in nine patients with LGI1 antibodies. Results: Psychiatric and cognitive symptoms were common, as were tonic seizures associated with EEG electrodecremental events (often with the so-called faciobrachial dystonic semiology). A rarity or absence of interictal epileptiform discharges contrasted with frequent subclinical temporal lobe seizures in some patients, which at times showed characteristics similar to subclinical rhythmic electrographic discharges of adults (SREDA), including sensitivity to hyperventilation. Conclusions: LGI1-antibody mediated encephalitis may be associated with tonic seizures and corresponding electrodecremental events, as well as an unusual SREDA-like pattern of frequent subclinical temporal lobe seizures, which may be triggered by hyperventilation, all in the setting of rare interictal epileptiform discharges.

scholarly journals Olfactory stimulus-induced temporal lobe seizures in limbic encephalitis

Seizure ◽  
2019 ◽  
Vol 69 ◽  
pp. 204-206 ◽  
Author(s):  
Federica Avorio ◽  
Alessandra Morano ◽  
Martina Fanella ◽  
Jinane Fattouch ◽  
Mariarita Albini ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Limbic Encephalitis ◽  
Olfactory Stimulus ◽  
Temporal Lobe Seizures

Ondine's curse and temporal lobe seizures: anti-Hu- and Zic4-associated paraneoplastic brainstem and limbic encephalitis

2018 ◽  
Vol 25 (5) ◽  
pp. e59-e60 ◽  
Author(s):  
L. Kay ◽  
S. Bauer ◽  
A. R. Koczulla ◽  
D. Librizzi ◽  
D. Vadasz ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Limbic Encephalitis ◽  
Ondine’S Curse ◽  
Temporal Lobe Seizures ◽  
Ondine's Curse

ASL MRI and 18F-FDG-PET in autoimmune limbic encephalitis: clues from two paradigmatic cases

2021 ◽  
Author(s):  
Alessandro Dinoto ◽  
Marta Cheli ◽  
Miloš Ajčević ◽  
Franca Dore ◽  
Carmelo Crisafulli ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Limbic Encephalitis ◽  
Autoimmune Limbic Encephalitis ◽  
18F Fdg

Botryoid nuclei of neutrophils and monocytes in autoimmune limbic encephalitis

2012 ◽  
Vol 95 (4) ◽  
pp. 329-330 ◽  
Author(s):  
Akihito Fujimi ◽  
Yuki Ikeda ◽  
Kaoru Ono ◽  
Yuji Kanisawa
Keyword(s):  
Limbic Encephalitis ◽  
Autoimmune Limbic Encephalitis

scholarly journals Electroencephalographic Features of Temporal Lobe Epilepsy

2010 ◽  
Vol 37 (4) ◽  
pp. 439-448 ◽  
Author(s):  
Mohammed M. Jan ◽  
Mark Sadler ◽  
Susan R. Rahey
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Surgical Management ◽  
Temporal Lobe ◽  
Seizure Onset ◽  
Resective Surgery ◽  
Accurate Localization ◽  
Epileptiform Discharges ◽  
Ictal Eeg ◽  
Temporal Lobe Seizures ◽  
Eeg Recordings

Electroencephalography (EEG) is an important tool for diagnosing, lateralizing and localizing temporal lobe seizures. In this paper, we review the EEG characteristics of temporal lobe epilepsy (TLE). Several “non-standard” electrodes may be needed to further evaluate the EEG localization, Ictal EEG recording is a major component of preoperative protocols for surgical consideration. Various ictal rhythms have been described including background attenuation, start-stop-start phenomenon, irregular 2-5 Hz lateralized activity, and 5-10 Hz sinusoidal waves or repetitive epileptiform discharges. The postictal EEG can also provide valuable lateralizing information. Postictal delta can be lateralized in 60% of patients with TLE and is concordant with the side of seizure onset in most patients. When patients are being considered for resective surgery, invasive EEG recordings may be needed. Accurate localization of the seizure onset in these patients is required for successful surgical management.

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