scholarly journals Quantitative MRI of the brachial plexus shows specific changes in nerve architecture in CIDP, MMN and motor neuron disease

2021 ◽  
Author(s):  
Marieke van Rosmalen ◽  
H. Stephan Goedee ◽  
Rosina Derks ◽  
Fay‐Lynn Asselman ◽  
Camiel Verhamme ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Brachial Plexus ◽  
Motor Neuron Disease ◽  
Quantitative Mri

Thr124Met myelin protein zero mutation mimicking motor neuron disease

2021 ◽  
pp. 1-6
Author(s):  
Giulia Bisogni ◽  
Angela Romano ◽  
Amelia Conte ◽  
Giorgio Tasca ◽  
Daniela Bernardo ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Myelin Protein ◽  
Myelin Protein Zero ◽  
Protein Zero

Late onset Sandhoff disease presenting with lower motor neuron disease and stuttering

2021 ◽  
Author(s):  
Jorge Alonso-Pérez ◽  
Ana Casasús ◽  
Álvaro Gimenez-Muñoz ◽  
Jennifer Duff ◽  
Ricard Rojas-Garcia ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Late Onset ◽  
Sandhoff Disease ◽  
Lower Motor Neuron ◽  
Lower Motor Neuron Disease

scholarly journals Longitudinal clinical and neuroanatomical correlates of memory impairment in motor neuron disease

2021 ◽  
Vol 29 ◽  
pp. 102545
Author(s):  
Judith Machts ◽  
Marius Keute ◽  
Joern Kaufmann ◽  
Stefanie Schreiber ◽  
Elisabeth Kasper ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Memory Impairment

Atypical motor neuron disease with severe ophthalmoloplegia: a report of two cases

1995 ◽  
Vol 242 (8) ◽  
pp. 541-546 ◽  
Author(s):  
N. Yuki ◽  
M. Yamada ◽  
T. Yuasa ◽  
K. Kaneko ◽  
T. Inuzuka ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease

scholarly journals ALS-Like Disorder in Three HIV-Positive Patients: Case Series

2021 ◽  
pp. 59-64
Author(s):  
Zachary Aaron Satin ◽  
Elham Bayat
Keyword(s):  
Antiretroviral Therapy ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Motor Neurons ◽  
Case Series ◽  
Retrospective Chart Review ◽  
Effective Control ◽  
Hiv Positive ◽  
Disease Course ◽  
Retroviral Infection

There appears to be a relationship between retroviruses such as HIV and the development of an ALS-like syndrome. Few cases have been reported; however, there exists evidence of a higher frequency of motor neuron disease in HIV-infected patients, as well as potential slowing and reversibility of disease course with combination antiretroviral therapy. We conducted a retrospective chart review of patients presenting to the George Washington University ALS Clinic from September 2006 to June 2018 to identify patients with HIV receiving HAART who were subsequently diagnosed with ALS or an ALS-like disorder. Our goals were to describe our patients’ disease course and compare them to general characteristics of ALS. We report three cases of HIV-positive individuals, all male, who were subsequently diagnosed with ALS. Each presented with symptoms of limb onset ALS with involvement of upper and lower motor neurons and whose disease originated at the cervical level. All three had been diagnosed with HIV prior to presentation and were presumably compliant with antiretroviral therapy throughout. Our patients demonstrated effective control of their HIV infection. Each experienced relatively slow progression of motor impairment compared to general ALS characteristics. Our study offers a distinct profile of HIV-positive patients compliant with HAART subsequently diagnosed with an ALS-like disorder. Further study should aim to uncover pathophysiological similarities between motor neuron disease both in the presence and absence of retroviral infection and to develop effective medical therapy for each.

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