Plaque neovascularization detected with contrast‐enhanced ultrasound predicts ischaemic stroke recurrence in patients with carotid atherosclerosis

2020 ◽  
Vol 27 (5) ◽  
pp. 809-816 ◽  
Author(s):  
P. Camps‐Renom ◽  
L. Prats‐Sánchez ◽  
F. Casoni ◽  
J. M. González‐de‐Echávarri ◽  
P. Marrero‐González ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Carotid Atherosclerosis ◽  
Stroke Recurrence ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

scholarly journals 3D contrast enhanced ultrasound of carotid atherosclerosis

2011 ◽  
Vol 9 (7) ◽  
pp. 558
Author(s):  
Ankur Thapar ◽  
Joseph Shalhoub ◽  
David Owen ◽  
Alun Davies ◽  
Edward Leen
Keyword(s):  
Carotid Atherosclerosis ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Carotid Intraplaque Neovascularization Predicts Ischemic Stroke Recurrence in Patients with Carotid Atherosclerosis

Gerontology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Yan Song ◽  
Ying Dang ◽  
Jichang Wang ◽  
Hui Cai ◽  
Jun Feng ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Carotid Stenosis ◽  
Carotid Atherosclerosis ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Stroke Recurrence ◽  
Contrast Enhanced ◽  
Significant Difference ◽  
A Prospective Study

<b><i>Introduction:</i></b> This study aimed to examine whether intraplaque neovascularization (IPN) of carotid plaques, as characterized by contrast-enhanced ultrasound (CEUS), is associated with ischemic stroke recurrence in patients with carotid atherosclerosis. <b><i>Methods:</i></b> We conducted a prospective study of consecutive patients with a recent stroke and at least one atherosclerotic plaque in the carotid artery on the side consistent with symptoms. All patients underwent CEUS after their first admission. IPN was graded on the basis of the presence and location of microbubbles within each plaque. <b><i>Results:</i></b> We eventually included 155 patients, all of whom underwent IPN analysis. After a follow-up of 24 months, we recorded 25 (16.1%) stroke recurrences in the whole population. All the recurrences occurred in patients presenting IPN. There was significant difference in the IPN between the 2 groups (<i>p</i> = 0.002). In the final Cox proportional-hazards multivariable models, IPN of grade 2 was independently associated with the risk of stroke recurrence (HR = 4.535; 95% CI: 1.892–10.870; <i>p</i> = 0.001). This association remained after adjusting for the degree of carotid stenosis (HR = 3.491; 95% CI: 1.410–8.646; <i>p</i> = 0.007). <b><i>Conclusions:</i></b> IPN was an independent predictor of stroke recurrence in patients with a recent ischemic stroke and carotid atherosclerosis. In predicting stroke recurrence, IPN may be an earlier indicator than carotid stenosis and may help stratify the risk of stroke recurrence.

scholarly journals Late-Phase Contrast-Enhanced Ultrasound Reflects Biological Features of Instability in Human Carotid Atherosclerosis

Stroke ◽  
2011 ◽  
Vol 42 (12) ◽  
pp. 3634-3636 ◽  
Author(s):  
Joseph Shalhoub ◽  
Claudia Monaco ◽  
David R.J. Owen ◽  
Thomas Gauthier ◽  
Ankur Thapar ◽  
...  
Keyword(s):  
Phase Contrast ◽  
Carotid Atherosclerosis ◽  
Late Phase ◽  
Contrast Enhanced Ultrasound ◽  
Biological Features ◽  
Contrast Enhanced ◽  
Human Carotid

Usefulness of Contrast-Enhanced Ultrasound for Detection of Carotid Plaque Ulceration in Patients With Symptomatic Carotid Atherosclerosis

2013 ◽  
Vol 112 (2) ◽  
pp. 292-298 ◽  
Author(s):  
Gerrit L. ten Kate ◽  
Anouk C. van Dijk ◽  
Stijn C.H. van den Oord ◽  
Burhan Hussain ◽  
Hence J.M. Verhagen ◽  
...  
Keyword(s):  
Carotid Plaque ◽  
Carotid Atherosclerosis ◽  
Contrast Enhanced Ultrasound ◽  
Symptomatic Carotid ◽  
Contrast Enhanced ◽  
Plaque Ulceration

scholarly journals Current status and future developments of contrast-enhanced ultrasound of carotid atherosclerosis

2013 ◽  
Vol 57 (2) ◽  
pp. 539-546 ◽  
Author(s):  
Gerrit L. ten Kate ◽  
Stijn C.H. van den Oord ◽  
Eric J.G. Sijbrands ◽  
Aad van der Lugt ◽  
Nico de Jong ◽  
...  
Keyword(s):  
Carotid Atherosclerosis ◽  
Current Status ◽  
Contrast Enhanced Ultrasound ◽  
Future Developments ◽  
Contrast Enhanced
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