Safety of tapering tacrolimus dose in patients with well‐controlled anti‐acetylcholine receptor antibody‐positive myasthenia gravis

2019 ◽  
Vol 27 (1) ◽  
pp. 100-104 ◽  
Author(s):  
Y. Nishida ◽  
Y. K. Takahashi ◽  
T. Kanai ◽  
Y. Nose ◽  
S. Ishibashi ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
Receptor Antibody ◽  
Acetylcholine Receptor Antibody ◽  
Tacrolimus Dose ◽  
Anti Acetylcholine

scholarly journals The Anti-Acetylcholine Receptor Antibody Test in Suspected Ocular Myasthenia Gravis

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Jung Jin Lee ◽  
Kyung Min Koh ◽  
Ungsoo Samuel Kim
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
Antibody Test ◽  
Thyroid Autoantibodies ◽  
Thyroid Autoantibody ◽  
Receptor Antibody ◽  
Ocular Myasthenia ◽  
Acetylcholine Receptor Antibody ◽  
Ocular Myasthenia Gravis ◽  
Anti Acetylcholine

Aim. To estimate the clinical significance of anti-acetylcholine receptor antibody (anti-AChR-Ab) levels in suspected ocular myasthenia gravis.Methods. In total, 144 patients complaining of fluctuating diplopia and ptosis were evaluated for serum levels of anti-acetylcholine receptor antibody and their medical charts were retrospectively reviewed. Subjects were classified into three groups: variable diplopia only, ptosis only, and both variable diplopia and ptosis. We investigated serum anti-AChR-Ab titer levels and performed thyroid autoantibody tests.Results. Patients’ chief complaints were diplopia (N=103), ptosis (N=12), and their concurrence (N=29). Abnormal anti-AChR-Ab was observed in 21 of 144 patients (14.1%). Between the three groups, mean age, number of seropositive patients, and mean anti-AChR-Ab level were not significantly different (P=0.224, 0.073, and 0.062, resp.). Overall, 27.5% of patients had abnormal thyroid autoantibodies.Conclusion. The sensitivity of anti-AChR-Ab was 14.1% in suspected ocular myasthenia gravis and seropositivity in myasthenia gravis patients showed a high correlation with the presence of thyroid autoantibodies.

Multiple forms of anti-acetylcholine receptor antibody in myasthenia gravis

1981 ◽  
Vol 4 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Tom Mittag ◽  
Tobias Massa ◽  
Peter Kornfeld ◽  
Angelos Papatestas ◽  
Adam Bender ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Acetylcholine Receptor ◽  
Multiple Forms ◽  
Receptor Antibody ◽  
Acetylcholine Receptor Antibody ◽  
Anti Acetylcholine
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