Seasonal variation of vitamin D and Epstein−Barr virus antibody in multiple sclerosis patients

2018 ◽  
Vol 25 (9) ◽  
pp. e103-e103 ◽  
Author(s):  
M. Farrokhi
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Seasonal Variation ◽  
Epstein Barr Virus ◽  
Virus Antibody ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients

Vitamin D, HLA-DRB1 and Epstein-Barr virus antibody levels in a prospective cohort of multiple sclerosis patients

2016 ◽  
Vol 23 (6) ◽  
pp. 1064-1070 ◽  
Author(s):  
S. Wergeland ◽  
K.-M. Myhr ◽  
K. I. Løken-Amsrud ◽  
A. G. Beiske ◽  
K. S. Bjerve ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Prospective Cohort ◽  
Epstein Barr Virus ◽  
Virus Antibody ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients ◽  
Antibody Levels

Vitamin D supplementation and antibodies against the Epstein-Barr virus in multiple sclerosis patients

2013 ◽  
Vol 19 (12) ◽  
pp. 1679-1680 ◽  
Author(s):  
Giulio Disanto ◽  
Adam E Handel ◽  
Jan Damoiseaux ◽  
Raymond Hupperts ◽  
Gavin Giovannoni ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Epstein Barr Virus ◽  
Vitamin D Supplementation ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients

Illuminating the in vitro effects of Epstein-Barr virus and vitamin D on immune response in multiple sclerosis patients

2021 ◽  
Author(s):  
Majid Teymoori-Rad ◽  
Mohammad Ali Sahraian ◽  
Talat Mokhtariazad ◽  
Ahmad Nejati ◽  
Razieh Sadat Kazemi Mozdabadi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Immune Response ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
In Vitro Effects ◽  
Multiple Sclerosis Patients

scholarly journals Evaluation of Epstein-Barr virus-specific antibodies in Cypriot multiple sclerosis patients

2019 ◽  
Vol 105 ◽  
pp. 270-275 ◽  
Author(s):  
Elie Deeba ◽  
Dana Koptides ◽  
Efthychia Gaglia ◽  
Astero Constantinou ◽  
Anastasia Lambrianides ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Epstein Barr Virus ◽  
Specific Antibodies ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients

Production of retrovirus and Epstein-Barr virus in cell lines from multiple sclerosis patients

1997 ◽  
Vol 95 ◽  
pp. 65-69 ◽  
Author(s):  
M. Munch ◽  
A. Møller-Larsen ◽  
T. Christensen ◽  
N. Morling ◽  
H. J. Hansen ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cell Lines ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients

Epstein-Barr virus-specific antibody response in cerebrospinal fluid and serum of patients with multiple sclerosis

2010 ◽  
Vol 16 (7) ◽  
pp. 883-887 ◽  
Author(s):  
Massimiliano Castellazzi ◽  
Carmine Tamborino ◽  
Alice Cani ◽  
Elena Negri ◽  
Eleonora Baldi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Neurological Disorders ◽  
Epstein Barr Virus ◽  
Serum Levels ◽  
Nuclear Antigen ◽  
Enzyme Linked Immunosorbent Assay ◽  
Barr Virus ◽  
Epstein Barr ◽  
Multiple Sclerosis Patients

Cerebrospinal fluid and serum levels and intrathecal synthesis of anti-Epstein—Barr virus (EBV) IgG were measured by enzyme-linked immunosorbent assay in 80 relapsing—remitting multiple sclerosis patients grouped according to clinical and magnetic resonance imaging (MRI) evidence of disease activity. Eighty patients with other inflammatory neurological disorders (OIND) and 80 patients with non-inflammatory neurological disorders (NIND) served as neurological controls. Cerebrospinal fluid concentrations were higher in OIND than in multiple sclerosis ( p < 0.0001) and NIND ( p < 0.01) for anti-viral-capsid-antigen (anti-VCA) IgG, in multiple sclerosis than in NIND ( p < 0.01) and in OIND than in NIND ( p < 0.05) for anti-EBV nuclear antigen-1 (EBNA-1) IgG. Serum levels were more elevated in OIND than in multiple sclerosis ( p < 0.05) and in MRI inactive than in MRI active multiple sclerosis ( p < 0.0001) for anti-VCA IgG, and in multiple sclerosis than in OIND and NIND ( p < 0.01) for anti-EBNA-1 IgG. Serum titres of anti-VCA and anti-EBNA-1 IgG were also positively ( p < 0.05) and inversely ( p < 0.001) correlated, respectively, with the Expanded Disability Status Scale. An intrathecal IgG production of anti-VCA and anti-EBNA-1 IgG, as indicated by Antibody Index, was present only in a limited number of multiple sclerosis patients and controls (range from 1.3 to 6.3%). These findings do not support a direct pathogenetic role of EBV-targeted humoral immune response in multiple sclerosis.

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