Serum 25-hydroxyvitamin D deficiency predicts poor outcome amongst acute ischaemic stroke patients with low high density lipoprotein cholesterol

2016 ◽  
Vol 23 (12) ◽  
pp. 1763-1768 ◽  
Author(s):  
T. Xu ◽  
C. Zhong ◽  
Y. Peng ◽  
C.-S. Chen ◽  
J. Wang ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Ischaemic Stroke ◽  
High Density Lipoprotein Cholesterol ◽  
Acute Ischaemic Stroke ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Stroke Patients ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

scholarly journals Evaluation of High Density Lipoprotein Cholesterol Concentrations among Elderly Ischaemic Stroke Patients

2018 ◽  
Vol 13 (1) ◽  
pp. 8-12
Author(s):  
Kazi Jannat Ara ◽  
Abu Shams Md Hasan Ali Masum ◽  
Md Shafiqus Saleheen ◽  
Sheikh Abdul Kader ◽  
Sk Mahbub Alam ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Ischaemic Stroke ◽  
High Density Lipoprotein Cholesterol ◽  
Heart Diseases ◽  
Smoking Habit ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Stroke Patients ◽  
Female Ratio

Stroke is an alarming health hazard all over the world as well as in Bangladesh and one of the leading causes of mortality and morbidity. There is a well-established inverse relation between serum concentrations of high density lipoprotein cholesterol (HDL-c) and the risk of coronary heart diseases but it is not a welldocumented risk factor for stroke. This study was done to evaluate of the HLD-c concentration among elderly ischaemic stroke patients. This cross sectional study was conducted in Out Patient department (OPD) stroke clinic and Indoor of the department of neurology, BSMMU, Dhaka from July 2015 to June 2016. A total 200 patients suffering from ischaemic stroke within the range of 61-95 years of age of both sexes with TIA, and hemorrhagic stroke were included. Patient with Stoke after one month of onset, cases with anti-lipid drugs were excluded. Male and female ratio was 1.95:1. Mean age was 68.4±8.24 years. 75 (52.8%) patients had hypertension, 20 (14.1%) had diabetes mellitus,10 (7.0%)patients had atrial fibrillation,8(5.6%)had ischemic heart disease. 44 (31.0%) patients had smoking habit ,mean total cholesterol was 190.7±56.0 mg/dl, mean HDL was36.9±8.4mg/dl, mean LDL was123.9±38.8mg/dl and mean Triglyceride was 175.9±70.5 mg/dl. HDL level gradually decreased according to the increment of age. HDL-c is low in elderly ischaemic stroke patient.University Heart Journal Vol. 13, No. 1, January 2017; 8-12

scholarly journals Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

2019 ◽  
Author(s):  
Yanan Wang ◽  
Quhong Song ◽  
Yajun Cheng ◽  
Chenchen Wei ◽  
Chen Ye ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Ischaemic Stroke ◽  
High Density Lipoprotein Cholesterol ◽  
Acute Ischaemic Stroke ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Predictive Values ◽  
Haemorrhagic Transformation ◽  
Increased Risk

Abstract Background: It is unclear whether non-high-density lipoprotein cholesterol (Non-HDL-C) is associated with haemorrhagic transformation (HT) after acute ischaemic stroke (AIS). We aimed to explore the association between Non-HDL-C and HT, as well as compare predictive values of Non-HDL-C and low-density lipoprotein cholesterol (LDL-C) for HT.Methods: We consecutively enrolled AIS patients within 7 days of stroke onset. Participants were divided into four categories according to quartiles of Non-HDL-C. HT was assessed by follow-up brain imaging. We assessed the association between Non-HDL-C, LDL-C and HT.Results: A total of 2043 patients were included, among whom 232 were identified as HT. Compared with the highest quartiles, the first, second and third quartiles of Non-HDL-C were associated with increased risk of HT (adjusted Odds ratios [ORs] 1.74 [95% Confidence Interval [CI] 1.09-2.78], 2.01[95% CI 1.26-3.20], and 1.76 [95% CI 1.10-2.83], respectively, P for trend=0.024). Similar results were found for LDL-C. There was significant interaction between Non-HDL-C and age (P for interaction=0.021). The addition of Non-HDL-C and LDL-C to conventional factors significantly improved predictive values (Non-HDL-C, net reclassification index [NRI] 0.24, 95%CI 0.17-0.31, P<0.001; LDL-C, NRI 0.15, 95%CI 0.08-0.22, P=0.03).Conclusions: Low Non-HDL-C was associated with increased risks of HT. In addition, Non-HDL-C has similar effects as LDL-C for predicting HT.

scholarly journals Association between non-high-density lipoprotein cholesterol and haemorrhagic transformation in patients with acute ischaemic stroke

2019 ◽  
Author(s):  
Yanan Wang ◽  
Quhong Song ◽  
Yajun Cheng ◽  
Chenchen Wei ◽  
Chen Ye ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Ischaemic Stroke ◽  
High Density Lipoprotein Cholesterol ◽  
Acute Ischaemic Stroke ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Predictive Values ◽  
Haemorrhagic Transformation ◽  
Increased Risk

Abstract Background : It is unclear whether non-high-density lipoprotein cholesterol (Non-HDL-C) is associated with haemorrhagic transformation (HT) after acute ischaemic stroke (AIS). We aimed to explore the association between Non-HDL-C and HT, as well as compare the predictive values of Non-HDL-C and low-density lipoprotein cholesterol (LDL-C) for HT. Methods: We consecutively enrolled AIS patients within 7 days of stroke onset. Participants were divided into four categories according to quartiles of Non-HDL-C. HT was assessed by follow-up brain imaging. We assessed the association between Non-HDL-C, LDL-C and HT in multivariate logistic regression analysis. Results: A total of 2043 patients were included, among whom 232 were identified as HT. Compared with the highest quartiles, the first, second and third quartiles of Non-HDL-C were associated with increased risk of HT (adjusted Odds ratios [ORs] 1.74 [95% Confidence Interval [CI] 1.09-2.78], 2.01[95% CI 1.26-3.20], and 1.76 [95% CI 1.10-2.83], respectively, P for trend=0.024). Similar results were found for LDL-C. There was significant interaction between Non-HDL-C and age ( P for interaction=0.021). The addition of Non-HDL-C and LDL-C to conventional factors significantly improved predictive values (Non-HDL-C, net reclassification index [NRI] 0.24, 95%CI 0.17-0.31, P<0.001; LDL-C, NRI 0.15, 95%CI 0.08-0.22, P=0.03). Conclusions: Low Non-HDL-C was associated with increased risks of HT. In addition, Non-HDL-C has similar effects as LDL-C for predicting HT. Keywords: Non-high-density lipoprotein cholesterol, Haemorrhagic transformation, Acute ischaemic stroke

The influence of 25-hydroxyvitamin D and High-Density Lipoprotein Cholesterol on BIA Resistance results and aging on BIA Reactance results in elderly people

2018 ◽  
Vol 27 ◽  
pp. 92-95 ◽  
Author(s):  
Vanessa Amarante Carvalho ◽  
Patricia Ferreira do Prado Moreira ◽  
Neide Alessandra Périgo Nascimento ◽  
Audrey Andrade Bertolini ◽  
Levy Aragão ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Elderly People ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D
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