scholarly journals Gut microbiota in early pediatric multiple sclerosis: a case−control study

2016 ◽  
Vol 23 (8) ◽  
pp. 1308-1321 ◽  
Author(s):  
H. Tremlett ◽  
D. W. Fadrosh ◽  
A. A. Faruqi ◽  
F. Zhu ◽  
J. Hart ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Gut Microbiota ◽  
Case Control Study ◽  
Case Control ◽  
Pediatric Multiple Sclerosis ◽  
Control Study

scholarly journals Gut microbiota composition and arterial stiffness measured by pulse wave velocity: case–control study protocol (MIVAS study)

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e038933
Author(s):  
Rita Salvado ◽  
Sandra Santos-Minguez ◽  
Cristina Agudo-Conde ◽  
Cristina Lugones-Sanchez ◽  
Angela Cabo-Laso ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Gut Microbiota ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Intestinal Microbiota ◽  
Pulse Wave ◽  
Case Control Study ◽  
Case Control ◽  
Microbiota Composition ◽  
Control Study

IntroductionIntestinal microbiota is arising as a new element in the physiopathology of cardiovascular diseases. A healthy microbiota includes a balanced representation of bacteria with health promotion functions (symbiotes). The aim of this study is to analyse the relationship between intestinal microbiota composition and arterial stiffness.Methods and analysisAn observational case—control study will be developed. Cases will be defined by the presence of at least one of the following: carotid-femoral pulse wave velocity (cf-PWV), Cardio-Ankle Vascular Index (CAVI), brachial ankle pulse wave velocity (ba or ba-PWV) above the 90th percentile, for age and sex, of the reference population. Controls will be selected from the same population as cases. The study will be developed in Primary Healthcare Centres. We will select 500 subjects (250 cases and 250 controls), between 45 and 74 years of age. Cases will be selected from a database that combines data from EVA study (Spain) and Guimarães/Vizela study (Portugal). Measurements: cf-PWV will be measured using the SphygmoCor system, CAVI, ba-PWV and Ankle-Brachial Index will be determined using VaSera device. Gut microbiome composition in faecal samples will be determined by 16S ribosomal RNA sequencing. Lifestyle will be assessed by food frequency questionnaire, adherence to the Mediterranean diet and IPAQ (International Physical Activity Questionnaire). Body composition will be evaluated by bioimpedance.Ethics and disseminationThe study has been approved by ‘Committee of ethics of research with medicines of the health area of Salamanca’ on 14 December 2018 (cod. 2018-11-136) and the ’Ethics committee for health of Guimaraes’ (Portugal) on 15 October 2019 (ref: 67/2019). All study participants will sign an informed consent form agreeing to participate in the study, in compliance with the Declaration of Helsinki and the WHO standards for observational studies. The results of this study will allow a better description of gut microbiota in patients with arterial stiffness.Trial registration detailsClinicalTrials.gov, identifier NCT03900338

scholarly journals Estimating the Marginal Causal Effect of Fish Consumption during Adolescence on Multiple Sclerosis: A Population-Based Incident Case-Control Study

2018 ◽  
Vol 50 (3-4) ◽  
pp. 111-118 ◽  
Author(s):  
Ibrahim Abdollahpour ◽  
Saharnaz Nedjat ◽  
Mohammad Ali Mansournia ◽  
Mohammad Ali Sahraian ◽  
Jay S. Kaufman
Keyword(s):  
Multiple Sclerosis ◽  
Fish Consumption ◽  
Case Control Study ◽  
Causal Effect ◽  
Population Based ◽  
Case Control ◽  
Incident Case ◽  
Control Study

Restless leg syndrome and multiple sclerosis: a case-control study in China

2015 ◽  
Vol 19 (4) ◽  
pp. 1355-1360 ◽  
Author(s):  
Gangqiong Liu ◽  
Xiao Feng ◽  
Chao Lan ◽  
Ziqiang Zhu ◽  
Shengli Ma ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Restless Leg Syndrome ◽  
Control Study

Lifestyle Factors and Multiple Sclerosis: A Case-Control Study in Belgrade

2006 ◽  
Vol 27 (4) ◽  
pp. 212-216 ◽  
Author(s):  
Tatjana Pekmezovic ◽  
Jelena Drulovic ◽  
Marija Milenkovic ◽  
Mirjana Jarebinski ◽  
Nebojsa Stojsavljevic ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Lifestyle Factors ◽  
Control Study

scholarly journals Multiple sclerosis is associated with high trait anger: A case–control study

2014 ◽  
Vol 340 (1-2) ◽  
pp. 69-74 ◽  
Author(s):  
Julián Benito-León ◽  
Andrés Labiano-Fontcuberta ◽  
Alex J. Mitchell ◽  
Moreno-García Sara ◽  
Pablo Martínez-Martín
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Trait Anger ◽  
High Trait ◽  
Control Study

Shared breastfeeding & other early multiple sclerosis risk factors: A case-control study

2021 ◽  
Vol 50 ◽  
pp. 102812
Author(s):  
Nuha M. Alkhawajah ◽  
Laith Hussain-Alkhateeb ◽  
Yafa A. Alshamlan ◽  
Mohammad Osama Almohaini ◽  
Ghadah A. Aleissa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Multiple Sclerosis Risk ◽  
Control Study

No association between socioeconomic status and risk of multiple sclerosis: A population-based incident case-control study in a developing country

2018 ◽  
Vol 25 ◽  
pp. 292-296 ◽  
Author(s):  
Ibrahim Abdollahpour ◽  
Saharnaz Nedjat ◽  
Yahya Salimi ◽  
Rahmatollah Moradzadeh ◽  
Mohammad Ali Mansournia ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Socioeconomic Status ◽  
Developing Country ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Incident Case ◽  
Control Study

scholarly journals Potential risk factors for multiple sclerosis in Rio de Janeiro: a case-control study

2009 ◽  
Vol 67 (2a) ◽  
pp. 229-234 ◽  
Author(s):  
Kátia Regina Penha da Silva ◽  
Regina Maria Papais Alvarenga ◽  
Oscar Fernandez y Fernandez ◽  
Hélcio Alvarenga ◽  
Luiz Claudio Santos Thuler
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Potential Risk ◽  
Rio De Janeiro ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Potential Risk Factors ◽  
Epidemiological Characteristics ◽  
Control Study

PURPOSE: To evaluate potential risk factors for the development of multiple sclerosis in Brazilian patients. METHOD: A case control study was carried out in 81 patients enrolled at the Department of Neurology of the Hospital da Lagoa in Rio de Janeiro, and 81 paired controls. A standardized questionnaire on demographic, social and cultural variables, and medical and family history was used. Statistical analysis was performed using descriptive statistics and conditional logistic regression models with the SPSS for Windows software program. RESULTS: Having standard vaccinations (vaccinations specified by the Brazilian government) (OR=16.2; 95% CI=2.3-115.2), smoking (OR=7.6; 95% CI=2.1-28.2), being single (OR=4.7; 95% CI=1.4-15.6) and eating animal brain (OR=3.4; 95% CI=1.2-9.8) increased the risk of developing MS. CONCLUSIONS: RESULTS of this study may contribute towards better awareness of the epidemiological characteristics of Brazilian patients with multiple sclerosis.

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