scholarly journals The Forced Swim Test: giving up on behavioral despair. (Commentary on Molendijk and de Kloet, 2021)

2021 ◽  
Author(s):  
Erin Gorman‐Sandler ◽  
Fiona Hollis
Keyword(s):  
Forced Swim Test ◽  
Behavioral Despair ◽  
Swim Test ◽  
Forced Swim

The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants

2007 ◽  
Vol 195 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Karsten M. Wicke ◽  
Andre Rex ◽  
Ana Jongen-Relo ◽  
Ilona Groth ◽  
Gerhard Gross
Keyword(s):  
Guinea Pig ◽  
Forced Swim Test ◽  
Behavioral Despair ◽  
Swim Test ◽  
Forced Swim

Stressors affect the response of male and female rats to clomipramine in a model of behavioral despair (forced swim test)

2005 ◽  
Vol 520 (1-3) ◽  
pp. 100-107 ◽  
Author(s):  
Daniele Consoli ◽  
Julia Fedotova ◽  
Vincenzo Micale ◽  
Nikolay S. Sapronov ◽  
Filippo Drago
Keyword(s):  
Forced Swim Test ◽  
Female Rats ◽  
Male And Female ◽  
Behavioral Despair ◽  
Swim Test ◽  
Forced Swim ◽  
Male And Female Rats

Acute restraint stress produces behavioral despair in weanling rats in the forced swim test

2009 ◽  
Vol 82 (2) ◽  
pp. 219-222 ◽  
Author(s):  
Blandina Bernal-Morales ◽  
Carlos M. Contreras ◽  
Jonathan Cueto-Escobedo
Keyword(s):  
Restraint Stress ◽  
Forced Swim Test ◽  
Behavioral Despair ◽  
Swim Test ◽  
Acute Restraint Stress ◽  
Forced Swim ◽  
Weanling Rats

Resistance to the development of stress-induced behavioral despair in the forced swim test associated with elevated hippocampal Bcl-xl expression

2010 ◽  
Vol 213 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Galina T. Shishkina ◽  
Tatyana S. Kalinina ◽  
Inna V. Berezova ◽  
Veta V. Bulygina ◽  
Nikolay N. Dygalo
Keyword(s):  
Forced Swim Test ◽  
Behavioral Despair ◽  
Swim Test ◽  
Forced Swim

Is immobility of rats in the forced swim test “behavioral despair?”

1988 ◽  
Vol 42 (1) ◽  
pp. 93-95 ◽  
Author(s):  
Hiroshi Nishimura ◽  
Akira Tsuda ◽  
Masanobi Oguchi ◽  
Yoshishige Ida ◽  
Masatoshi Tanaka
Keyword(s):  
Forced Swim Test ◽  
Behavioral Despair ◽  
Swim Test ◽  
Forced Swim

scholarly journals The Forced Swim Test as a Model of Depressive-like Behavior

10.3791/52587 ◽  
2015 ◽  
Author(s):  
Roni Yankelevitch-Yahav ◽  
Motty Franko ◽  
Avrham Huly ◽  
Ravid Doron
Keyword(s):  
Forced Swim Test ◽  
Swim Test ◽  
Forced Swim

scholarly journals Low-dose irradiation reduces forced swim test-induced immobility and oxidative stress in mice

2021 ◽  
Vol 165 ◽  
pp. 56-57
Author(s):  
Shota Naoe ◽  
Takahiro Kataoka ◽  
Hina Shuto ◽  
Junki Yano ◽  
Tetsuya Nakada ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Low Dose ◽  
Forced Swim Test ◽  
Swim Test ◽  
Dose Irradiation ◽  
Forced Swim ◽  
And Oxidative Stress

Additive interaction between scopolamine and nitric oxide agents on immobility in the forced swim test but not exploratory activity in the hole-board

2019 ◽  
Vol 236 (11) ◽  
pp. 3353-3362 ◽  
Author(s):  
Mohammad Nasehi ◽  
Mohammad-Hossein Mohammadi-Mahdiabadi-Hasani ◽  
Mohaddeseh Ebrahimi-Ghiri ◽  
Mohammad-Reza Zarrindast
Keyword(s):  
Nitric Oxide ◽  
Forced Swim Test ◽  
Exploratory Activity ◽  
Additive Interaction ◽  
Swim Test ◽  
Forced Swim ◽  
Hole Board

Standardised ginseng extract G115® potentiates the antidepressant-like properties of fluoxetine in the forced swim test

2021 ◽  
pp. 1-7
Author(s):  
Dylan J. Terstege ◽  
Debra S. MacDonald ◽  
R. Andrew Tasker
Keyword(s):  
Prefrontal Cortex ◽  
Forced Swim Test ◽  
Ginseng Root ◽  
Group Differences ◽  
Post Mortem ◽  
Ginseng Extract ◽  
Significant Group ◽  
Swim Test ◽  
Forced Swim ◽  
Plus Maze

Abstract Objective: Ginsenosides, biologically active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardised commercial ginseng extract, G115®, could reduce the signs of behavioural despair commonly observed in animal models of depression either alone or in combination with the selective serotonin reuptake inhibitor (SSRI) fluoxetine. Methods: Male Sprague-Dawley (SD) rats (N = 51) were divided into four groups: vehicle control, G115® ginseng root extract, fluoxetine and fluoxetine plus G115®. Rats were trained to voluntarily consume treatments twice daily for 14 days and were then tested in an open field (OF), elevated plus maze (EPM) and forced swim test (FST). Post-mortem hippocampal and prefrontal cortex tissue was analysed for expression of brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) by western blot. Results: One-way Analysis of Variance revealed no significant group differences in the OF or plus-maze performance on any variable examined. In the FST, fluoxetine significantly reduced immobility time and increased latency to immobility. The effects of fluoxetine were further significantly potentiated by co-administration of G115®. Post-mortem tissue analysis revealed significant group differences in BDNF expression in the left hippocampus and left prefrontal cortex without any accompanying changes in TrkB expression. Conclusions: We conclude that oral G115® significantly potentiates the antidepressant-like effect of fluoxetine in the FST in the absence of potentially confounding effects on locomotion and anxiety.

Sign in / Sign up

Export Citation Format

Share Document