scholarly journals A computational model‐based analysis of basal ganglia pathway changes in Parkinson’s disease inferred from resting‐state fMRI

2020 ◽  
Author(s):  
Oliver Maith ◽  
Francesc Villagrasa Escudero ◽  
Helge Ülo Dinkelbach ◽  
Javier Baladron ◽  
Andreas Horn ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Computational Model ◽  
Resting State ◽  
Resting State Fmri ◽  
Model Based ◽  
Model Based Analysis

scholarly journals Correction: Reduced Topological Efficiency in Cortical-Basal Ganglia Motor Network of Parkinson's Disease: A Resting State fMRI Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0139757
Author(s):  
Luqing Wei ◽  
Jiuquan Zhang ◽  
Zhiliang Long ◽  
Guo-Rong Wu ◽  
Xiaofei Hu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Resting State ◽  
Resting State Fmri ◽  
Motor Network ◽  
Fmri Study ◽  
Topological Efficiency

NEUROIMAGING OF IDIOPATHIC REM SLEEP BEHAVIOR DISORDER

2015 ◽  
Vol 86 (11) ◽  
pp. e4.95-e4
Author(s):  
Michal Rolinski ◽  
Ludovica Griffanti ◽  
Konrad Szewczyk-Krolikowski ◽  
Ricarda Menke ◽  
Timothy Quinnell ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Resting State ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Resting State Fmri ◽  
Precentral Gyrus ◽  
Sleep Behavior ◽  
Sensorimotor Network

IntroductionResting-state functional magnetic resonance imaging (rs-fMRI) studies have previously shown significantly impaired connectivity in patients within the early motor phase of Parkinson's disease. Is it possible to detect the same imaging signature of Parkinson's in RBD subjects, before a clinical diagnosis of Parkinson's disease is established?MethodsTwenty-six patients with polysomnography-proven RBD and twenty-two age- and sex-matched healthy controls were recruited into the study. All subjects underwent a comprehensive structural and resting-state MRI protocol.ResultsVoxel-based morphometry analysis did not yield any significant grey matter differences between the two groups. Similarly, no significant differences of fractional anisotropy were found using white matter tract analysis. Rs-fMRI revealed decreased coactivation within the basal ganglia network (involving the caudate, putamen, globus pallidus bilaterally) and the sensorimotor network (precentral gyrus) of patients with RBD. A small area of increased coactivation was found in the default mode network of patients with RBD.ConclusionsOur findings support the presence of basal ganglia dysfunction in patients with RBD, likely representing the prodromal stages of Parkinson's disease. Clinical and neuroimaging follow up is necessary to assess the clinical utility of resting state fMRI to predict the onset of Parkinson's disease in RBD subjects.

scholarly journals Reduced Topological Efficiency in Cortical-Basal Ganglia Motor Network of Parkinson's Disease: A Resting State fMRI Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e108124 ◽  
Author(s):  
Luqing Wei ◽  
Jiuquan Zhang ◽  
Zhiliang Long ◽  
Guo-Rong Wu ◽  
Xiaofei Hu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Resting State ◽  
Resting State Fmri ◽  
Motor Network ◽  
Fmri Study ◽  
Topological Efficiency

scholarly journals Correction: Reduced Topological Efficiency in Cortical-Basal Ganglia Motor Network of Parkinson's Disease: A Resting State fMRI Study

PLoS ONE ◽  
2018 ◽  
Vol 13 (7) ◽  
pp. e0200623
Author(s):  
Luqing Wei ◽  
Jiuquan Zhang ◽  
Zhiliang Long ◽  
Guo-Rong Wu ◽  
Xiaofei Hu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Basal Ganglia ◽  
Resting State ◽  
Resting State Fmri ◽  
Motor Network ◽  
Fmri Study ◽  
Topological Efficiency

Altered functional topography of the striatum in resting state fMRI in Parkinson's disease

2016 ◽  
Vol 22 ◽  
pp. e156
Author(s):  
Sun Nee Tan ◽  
Yiming Zhang ◽  
Aiping Liu ◽  
Jane Wang ◽  
Martin J. McKeown
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Resting State ◽  
Resting State Fmri ◽  
Functional Topography
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