scholarly journals Spontaneous resting-state gamma oscillations are not predictive of autistic traits in the general population

2018 ◽  
Vol 48 (8) ◽  
pp. 2928-2937 ◽  
Author(s):  
Kristel De Groot ◽  
Jan W. Van Strien
Keyword(s):  
General Population ◽  
Resting State ◽  
Autistic Traits ◽  
Gamma Oscillations

scholarly journals Developmental trajectories of autistic social traits in the general population

2021 ◽  
pp. 1-9
Author(s):  
Richard Pender ◽  
Pasco Fearon ◽  
Beate St Pourcain ◽  
Jon Heron ◽  
Will Mandy
Keyword(s):  
General Population ◽  
Full Range ◽  
Population Sample ◽  
Autistic Traits ◽  
Communication Disorders ◽  
Autism Spectrum ◽  
Growth Mixture Modelling ◽  
Autistic People ◽  
Social Difficulties ◽  
Autism Trait

Abstract Background Autistic people show diverse trajectories of autistic traits over time, a phenomenon labelled ‘chronogeneity’. For example, some show a decrease in symptoms, whilst others experience an intensification of difficulties. Autism spectrum disorder (ASD) is a dimensional condition, representing one end of a trait continuum that extends throughout the population. To date, no studies have investigated chronogeneity across the full range of autistic traits. We investigated the nature and clinical significance of autism trait chronogeneity in a large, general population sample. Methods Autistic social/communication traits (ASTs) were measured in the Avon Longitudinal Study of Parents and Children using the Social and Communication Disorders Checklist (SCDC) at ages 7, 10, 13 and 16 (N = 9744). We used Growth Mixture Modelling (GMM) to identify groups defined by their AST trajectories. Measures of ASD diagnosis, sex, IQ and mental health (internalising and externalising) were used to investigate external validity of the derived trajectory groups. Results The selected GMM model identified four AST trajectory groups: (i) Persistent High (2.3% of sample), (ii) Persistent Low (83.5%), (iii) Increasing (7.3%) and (iv) Decreasing (6.9%) trajectories. The Increasing group, in which females were a slight majority (53.2%), showed dramatic increases in SCDC scores during adolescence, accompanied by escalating internalising and externalising difficulties. Two-thirds (63.6%) of the Decreasing group were male. Conclusions Clinicians should note that for some young people autism-trait-like social difficulties first emerge during adolescence accompanied by problems with mood, anxiety, conduct and attention. A converse, majority-male group shows decreasing social difficulties during adolescence.

scholarly journals The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Michael C. W. English ◽  
Gilles E. Gignac ◽  
Troy A. W. Visser ◽  
Andrew J. O. Whitehouse ◽  
James T. Enns ◽  
...  
Keyword(s):  
Factor Analysis ◽  
General Population ◽  
Measurement Invariance ◽  
High Reliability ◽  
Predictive Ability ◽  
Autistic Traits ◽  
Autism Spectrum ◽  
Autism Spectrum Quotient ◽  
Sensory Sensitivity ◽  
Wide Range

Abstract Background Traits and characteristics qualitatively similar to those seen in diagnosed autism spectrum disorder can be found to varying degrees in the general population. To measure these traits and facilitate their use in autism research, several questionnaires have been developed that provide broad measures of autistic traits [e.g. Autism-Spectrum Quotient (AQ), Broad Autism Phenotype Questionnaire (BAPQ)]. However, since their development, our understanding of autism has grown considerably, and it is arguable that existing measures do not provide an ideal representation of the trait dimensions currently associated with autism. Our aim was to create a new measure of autistic traits that reflects our current understanding of autism, the Comprehensive Autism Trait Inventory (CATI). Methods In Study 1, 107 pilot items were administered to 1119 individuals in the general population and exploratory factor analysis of responses used to create the 42-item CATI comprising six subscales: Social Interactions, Communication, Social Camouflage, Repetitive Behaviours, Cognitive Rigidity, and Sensory Sensitivity. In Study 2, the CATI was administered to 1068 new individuals and confirmatory factor analysis used to verify the factor structure. The AQ and BAPQ were administered to validate the CATI, and additional autistic participants were recruited to compare the predictive ability of the measures. In Study 3, to validate the CATI subscales, the CATI was administered to 195 new individuals along with existing valid measures qualitatively similar to each CATI subscale. Results The CATI showed convergent validity at both the total-scale (r ≥ .79) and subscale level (r ≥ .68). The CATI also showed superior internal reliability for total-scale scores (α = .95) relative to the AQ (α = .90) and BAPQ (α = .94), consistently high reliability for subscales (α > .81), greater predictive ability for classifying autism (Youden’s Index = .62 vs .56–.59), and demonstrated measurement invariance for sex. Limitations Analyses of predictive ability for classifying autism depended upon self-reported diagnosis or identification of autism. The autistic sample was not large enough to test measurement invariance of autism diagnosis. Conclusions The CATI is a reliable and economical new measure that provides observations across a wide range of trait dimensions associated with autism, potentially precluding the need to administer multiple measures, and to our knowledge, the CATI is also the first broad measure of autistic traits to have dedicated subscales for social camouflage and sensory sensitivity.

scholarly journals Autistic Traits in the General Population

2003 ◽  
Vol 60 (5) ◽  
pp. 524 ◽  
Author(s):  
John N. Constantino ◽  
Richard D. Todd
Keyword(s):  
General Population ◽  
Autistic Traits

scholarly journals Stability of Autistic Traits from 5 to 8 Years of Age Among Children in the General Population

2018 ◽  
Vol 49 (1) ◽  
pp. 324-334 ◽  
Author(s):  
Hideyuki Haraguchi ◽  
Andrew Stickley ◽  
Aya Saito ◽  
Hidetoshi Takahashi ◽  
Yoko Kamio
Keyword(s):  
General Population ◽  
Autistic Traits

The Nature of Covariation Between Autistic Traits and Clumsiness: A Twin Study in a General Population Sample

2011 ◽  
Vol 41 (12) ◽  
pp. 1665-1674 ◽  
Author(s):  
Sara Moruzzi ◽  
Anna Ogliari ◽  
Angelica Ronald ◽  
Francesca Happé ◽  
Marco Battaglia
Keyword(s):  
General Population ◽  
Twin Study ◽  
Population Sample ◽  
Autistic Traits ◽  
General Population Sample

scholarly journals Autistic traits are associated with the functional connectivity of between—but not within—attention systems in the general population

2020 ◽  
Author(s):  
Sayaka Yoshimura ◽  
Kei Kobayashi ◽  
Tsukasa Ueno ◽  
Takashi Miyagi ◽  
Naoya Oishi ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
General Population ◽  
Executive Control ◽  
Autistic Traits ◽  
Autism Spectrum ◽  
Autism Spectrum Quotient ◽  
Functional Magnetic Resonance ◽  
Fmri Study ◽  
Trait Level ◽  
Attention Systems

Abstract Background: Previous studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical relationships among these systems. Additionally, other studies have reported that individuals with subclinical but high levels of autistic traits show similar attentional tendencies to those observed in ASD. Based on these findings, it was hypothesized that autistic traits would affect the functions and relationships of the three attention systems in a general population. Resting-state functional magnetic resonance imaging (fMRI) was performed in 119 healthy adults to investigate relationships between autistic traits and within- and between-system functional connectivity (FC) among the three attention systems. Twenty-six regions of interest that were defined as components of the three attention systems by a previous task-based fMRI study were examined in terms of within- and between-system FC. We assessed autistic traits using the Autism-Spectrum Quotient.Results: Correlational analyses revealed that autistic traits were significantly correlated with between-system FC, but not with within-system FC. Conclusions: Our results imply that a high autistic trait level, even when subclinical, is associated with the way the three attention systems interact.

scholarly journals No relationship between autistic traits and salivary testosterone concentrations in men from the general population

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0198779 ◽  
Author(s):  
Diana Weiting Tan ◽  
Murray T. Maybery ◽  
Michael W. Clarke ◽  
Renata Di Lorenzo ◽  
Melissa O. Evans ◽  
...  
Keyword(s):  
General Population ◽  
Autistic Traits ◽  
Salivary Testosterone

Autistic traits in Indian general population and patient group samples: distribution, factor structure, reliability and validity of the Autism-Spectrum Quotient

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Asmita Karmakar ◽  
Manisha Bhattacharya ◽  
Susmita Chatterjee ◽  
Atanu Kumar Dogra
Keyword(s):  
General Population ◽  
Factor Structure ◽  
Patient Group ◽  
Autistic Traits ◽  
Criterion Validity ◽  
Autism Spectrum ◽  
Group Differences ◽  
Autism Spectrum Quotient ◽  
Content Type ◽  
Compulsive Disorder

Purpose The Autism-Spectrum Quotient (AQ) is a widely used tool to quantify autistic traits in the general population. This study aims to report the distribution, group differences and factor structure of autistic traits in Indian general population. The work also assesses the criterion validity of AQ across three patient group samples – autism spectrum disorder (ASD), obsessive-compulsive disorder and social anxiety disorder. Design/methodology/approach In this study, psychometric properties of the adapted AQ were assessed among 450 neurotypical university students matched for age. Confirmatory factor analysis was done to see if the adapted AQ fits the original factor structure. Test–retest, internal consistency reliability and criterion validity were found out. Group differences (gender and field of study) in AQ were also assessed. Findings Autistic traits were found to be continuously distributed in the population, and patterns of group differences were consistent with previous studies. The adapted AQ had five factors resembling the original factor structure with a good fit, and 38 items instead of the original 50 items. Acceptable reliability coefficients were demonstrated along with criterion validity across clinical groups. Originality/value This work is the first to present the pattern of distribution and factor structure of autistic traits among neurotypical adults from Eastern India, a culturally different population, as well as a reliable and valid tool to assess autistic traits in Bengali, a language with 300 million speakers. The findings add to the growing literature on AQ measurement and the concept of autism as a quantitative trait, examined outside of the western samples.

scholarly journals Robust association between autistic traits and psychotic-like experiences in the adult general population: epidemiological study from the 2007 Adult Psychiatric Morbidity Survey and replication with the 2014 APMS

2020 ◽  
pp. 1-7
Author(s):  
Anton P. Martinez ◽  
Sophie Wickham ◽  
Georgina Rowse ◽  
Elizabeth Milne ◽  
Richard P. Bentall
Keyword(s):  
General Population ◽  
Psychiatric Morbidity ◽  
Autistic Traits ◽  
Cross Sectional ◽  
Increased Risk ◽  
Dependent Variables ◽  
Independent Variable ◽  
Logistic Regressions ◽  
Specific Symptoms ◽  
First Time

Abstract Background Studies have shown that there are overlapping traits and symptoms between autism and psychosis but no study to date has addressed this association from an epidemiological approach in the adult general population. Furthermore, it is not clear whether autistic traits are associated with specific symptoms of psychosis or with psychosis in general. We assess these associations for the first time by using the Adult Psychiatric Morbidity Survey (APMS) 2007 and the APMS 2014, predicting an association between autistic traits and probable psychosis, and specific associations between autistic traits and paranoia and strange experiences. Methods Participants (N = 7353 in 2007 and 7500 in 2014) completed the Psychosis Screening Questionnaire (PSQ) and a 20-item version of the Autism Quotient (AQ-20). Binomial logistic regressions were performed using AQ-20 as the independent variable and probable psychosis and specific symptoms as dependent variables. Results In the APMS 2007 dataset, significant associations were found between autism traits and probable psychosis, paranoia, thought insertion, and strange experiences. These results were replicated in APMS 2014 but with the additional significant association between autistic traits and hallucinations. Participants in the highest quartile of the AQ-20, compared with the lowest quartile, had an increased risk of probable psychosis of odds ratio (OR) = 15.5 [95% confidence interval (CI) 4.57–52.6] in APMS 2007 and OR = 22.5 (95% CI 7.64–66.3) in APMS 2014. Conclusions Autistic traits are strongly associated with probable psychosis and psychotic experiences with the exception of mania. Limitations such as the cross-sectional nature of the study are discussed.

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