Ovarian steroids alter dopamine receptor populations in the medial preoptic area of female rats: implications for sexual motivation, desire, and behaviour

2015 ◽  
Vol 42 (12) ◽  
pp. 3138-3148 ◽  
Author(s):  
M. Dean Graham ◽  
James Gardner Gregory ◽  
Dema Hussain ◽  
Wayne G. Brake ◽  
James G. Pfaus
Keyword(s):  
Dopamine Receptor ◽  
Preoptic Area ◽  
Sexual Motivation ◽  
Medial Preoptic Area ◽  
Female Rats ◽  
Ovarian Steroids

Induced Ovulation in Aged Female Rats by L-dopa Implants into the Medial Preoptic Area

1979 ◽  
Vol 28 (4) ◽  
pp. 234-240 ◽  
Author(s):  
R.L. Cooper ◽  
S.J. Brandt ◽  
M. Linnoila ◽  
R.F. Walker
Keyword(s):  
Preoptic Area ◽  
Medial Preoptic Area ◽  
Female Rats ◽  
Induced Ovulation

Estrogen, but not progesterone, induces the activity of nitric oxide synthase within the medial preoptic area in female rats

2014 ◽  
Vol 1578 ◽  
pp. 23-29 ◽  
Author(s):  
Fernanda Barbosa Lima ◽  
Fábio Honda Ota ◽  
Fernanda Jankur Cabral ◽  
Bruno Del Bianco Borges ◽  
Celso Rodrigues Franci
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Preoptic Area ◽  
Medial Preoptic Area ◽  
Female Rats ◽  
Oxide Synthase

Medial Preoptic Area, Estrogen, and the Peripubertal Desensitization to the Negative Estrogen Feedback in Female Rats

1984 ◽  
Vol 39 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Friedemann Döcke ◽  
Wolfgang Rohde ◽  
Peter Gerber ◽  
Gerold Kreuz
Keyword(s):  
Preoptic Area ◽  
Medial Preoptic Area ◽  
Female Rats

scholarly journals Region-, Neuron-, and Signaling Pathway-Specific Increases in Prolactin Responsiveness in Reproductively Experienced Female Rats

Endocrinology ◽  
2011 ◽  
Vol 152 (5) ◽  
pp. 1979-1988 ◽  
Author(s):  
Annika Sjoeholm ◽  
Robert S. Bridges ◽  
David R. Grattan ◽  
Greg M. Anderson
Keyword(s):  
Preoptic Area ◽  
Prolactin Receptor ◽  
Medial Preoptic Area ◽  
Receptor Expression ◽  
Dopamine Neurons ◽  
Female Rats ◽  
Reproductive Experience ◽  
Postpartum Disorders ◽  
Pregnancy And Lactation ◽  
Supraoptic Nuclei

Pregnancy and lactation cause long-lasting enhancements in maternal behavior and other physiological functions, along with increased hypothalamic prolactin receptor expression. To directly test whether reproductive experience increases prolactin responsiveness in the arcuate, paraventricular, and supraoptic nuclei and the medial preoptic area, female rats experienced a full pregnancy and lactation or remained as age-matched virgin controls. At 5 wk after weaning, rats received 2.5, 100, or 4000 ng ovine prolactin or vehicle intracerebroventricularly. The brains underwent immunohistochemistry for the phosphorylated forms of signal transducer and activator of transcription 5 (pSTAT5) or ERK1/2 (pERK1/2). There was a marked increase in pSTAT5 and pERK1/2 in response to prolactin in the regions examined in both virgin and primiparous rats. Primiparous rats exhibited approximately double the number of prolactin-induced pSTAT5-immunoreactive cells as virgins, this effect being most apparent at the higher prolactin doses in the medial preoptic area and paraventricular and supraoptic nuclei and at the lowest prolactin dose in the arcuate nucleus. Dual-label immunohistochemistry showed that arcuate kisspeptin (but not oxytocin or dopamine) neurons displayed increased sensitivity to prolactin in reproductively experienced animals; these neurons may contribute to the reduction in prolactin concentration observed after reproductive experience. There was no effect of reproductive experience on prolactin-induced pERK1/2, indicating a selective effect on the STAT5 pathway. These data show that STAT5 responsiveness to prolactin is enhanced by reproductive experience in multiple hypothalamic regions. The findings may have significant implications for understanding postpartum disorders affecting maternal care and other prolactin-associated pathologies.

Intracranial infusions of amphetamine into the medial preoptic area but not the nucleus accumbens affect paced mating behavior in female rats

2008 ◽  
Vol 89 (3) ◽  
pp. 253-262 ◽  
Author(s):  
Fay A. Guarraci ◽  
Russell J. Frohardt ◽  
Debra Hines ◽  
Erica Navaira ◽  
Julie Smith ◽  
...  
Keyword(s):  
Nucleus Accumbens ◽  
Mating Behavior ◽  
Preoptic Area ◽  
Medial Preoptic Area ◽  
Female Rats
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