scholarly journals Cholinergic excitation in mouse primary vs. associative cortex: region-specific magnitude and receptor balance

2014 ◽  
Vol 40 (4) ◽  
pp. 2608-2618 ◽  
Author(s):  
Michael K. Tian ◽  
Craig D. C. Bailey ◽  
Evelyn K. Lambe
Keyword(s):  
Associative Cortex

scholarly journals Segregation, connectivity, and gradients of deactivation in neural correlates of evidence in social decision making

2020 ◽  
Author(s):  
Roberto Viviani ◽  
Lisa Dommes ◽  
Julia E. Bosch ◽  
Karin Labek
Keyword(s):  
Decision Making ◽  
Social Cognition ◽  
Functional Imaging ◽  
Predictive Coding ◽  
Imaging Study ◽  
Neural Correlates ◽  
Laboratory Animals ◽  
Cortical Function ◽  
Cortical Organization ◽  
Associative Cortex

AbstractFunctional imaging studies of sensory decision making have detected a signal associated with evidence for decisions that is consistent with data from single-cell recordings in laboratory animals. However, the generality of this finding and its implications on our understanding of the organization of the fMRI signal are not clear. In the present functional imaging study, we investigated decisions in an elementary social cognition domain to identify the neural correlates of evidence, their segregation, connectivity, and their relationship to task deactivations. Besides providing data in support of an evidence-related signal in a social cognition task, we were interested in embedding these neural correlates in models of supramodal associative cortex placed at the top of a hierarchy of processing areas. Participants were asked to decide which of two depicted individuals was saddest based on information rich in sensory features (facial expressions) or through contextual cues suggesting the mental state of others (stylized drawings of mourning individuals). The signal associated with evidence for the decision was located in two distinct networks differentially recruited depending on the information type. Using the largest peaks of the signal associated with evidence as seeds in a database of connectivity data, these two networks were retrieved. Furthermore, the hubs of these networks were located near or along a ribbon of cortex located between task activations and deactivations between areas affected by perceptual priming and the deactivated areas of the default network system. In associative cortex, these findings suggest gradients of progressive relative deactivation as a possible neural correlate of the cortical organization envisaged by structural models of cortical organization and by predictive coding theories of cortical function.

scholarly journals The role of m1-cholinergic receptors in associative cortex of young rats in the performing autonomous regulation of heart rate during hypoxic exposure

2015 ◽  
Vol 17 (4) ◽  
Author(s):  
N. M. Volkova
Keyword(s):  
Atmospheric Pressure ◽  
Cholinergic Receptors ◽  
Hypoxic Exposure ◽  
Behavioral Reactions ◽  
Young Rats ◽  
Associative Cortex ◽  
Hypoxic Environment ◽  
Functional Consequences ◽  
Low Atmospheric Pressure

<p>It is known that human cholinergic transmission in the cerebral cortex required for cognitive and behavioral reactions. However, in the literature there is not enough experimental data on the role of m1‑cholinergic receptors<br />in associative cortex in young rats with incubation in hypoxic environment under conditions of low atmospheric pressure, considering the functional asymmetry of the cerebral hemispheres. The aim of the experiment was to determine the functional consequences of blocking m1‑cholinergic receptors in the associative cortex in young rats with incubation in hypoxic environment under conditions of low atmospheric pressure. Functional consequences of blocking m1‑cholinergic receptors in the associative cortex in young rats with incubation in hypoxic environment under conditions of low atmospheric pressure are different in the case of right-sided and left-sided application of pirenzepin.</p>

scholarly journals Progressive Focal Degenerative Disease of the Posterior Associative Cortex

1993 ◽  
Vol 20 (2) ◽  
pp. 154-157 ◽  
Author(s):  
Ezzedine Attig ◽  
Jean Jacquy ◽  
Patrick Uytdenhoef ◽  
Hervé Roland
Keyword(s):  
Degenerative Disease ◽  
Ct Scans ◽  
Occipital Region ◽  
Alzheimer Type ◽  
Visual Agnosia ◽  
Progressive Aphasia ◽  
Associative Cortex ◽  
Amnestic Syndrome ◽  
The Right ◽  
Occipital Horn

ABSTRACT:A 72-year-old man developed a very progressive neuropsychologic deficit 6 years ago, beginning with isolated visual topographic memory disturbances and visuo-constructive apraxia without additional manifestations of dementia. The syndrome worsened thereafter with the emergence of visual agnosia, simultagnosia, psychic paralysis of gaze, auditivo-verbal agnosia, and recently an amnestic syndrome with confabulation and confusion (at the end of 1989). CT scans, which remained unchanged over the years, showed mild, focal atrophic changes revealed by dilatation of the right occipital horn. His angiograms were normal. Two SPECT studies (with HMPAO measurements), performed 6 years from the onset, detected marked hypoperfusion in both parieto-occipital regions, mainly on the right side. Progressive focal degenerative disease without dementia is a relatively new syndrome, especially in cases with progressive aphasia.1 As noted in our patient, progressive disturbances initially localized in the right parieto-occipital region followed by posterior bilobar degeneration (pronounced on the right side) without dementia until late in the course may represent another exceptionally reported characteristic of this new syndrome. It is suggested that this variant of the Mesulam syndrome is more likely explained by progressive atrophy of the Alzheimer type.

Distributed population coding of multisensory spatial information in the associative cortex

2004 ◽  
Vol 20 (2) ◽  
pp. 525-529 ◽  
Author(s):  
Gyorgy Benedek ◽  
Gabriella Eordegh ◽  
Zoltan Chadaide ◽  
Attila Nagy
Keyword(s):  
Spatial Information ◽  
Population Coding ◽  
Associative Cortex
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