Lymphoid Malignancy in Common Variable Immunodeficiency in a Single Center Cohort

2021 ◽  
Author(s):  
Tukisa Smith ◽  
Charlotte Cunningham‐Rundles
Keyword(s):  
Common Variable Immunodeficiency ◽  
Lymphoid Malignancy ◽  
Single Center ◽  
Common Variable

scholarly journals Five Years of Experience in a Single Center: Retrospective Analysis of Adult Patients with Common Variable Immunodeficiency

2020 ◽  
Vol 18 (1) ◽  
pp. 30-37
Author(s):  
Gökhan AYTEKİN ◽  
Eray YILDIZ ◽  
Fatih ÇÖLKESEN ◽  
Şevket ARSLAN ◽  
Ahmet Zafer ÇALIŞKANER
Keyword(s):  
Retrospective Analysis ◽  
Common Variable Immunodeficiency ◽  
Adult Patients ◽  
Years Of Experience ◽  
Single Center ◽  
Common Variable

Clinical and immunological features of common variable immunodeficiency: a single center experience

2014 ◽  
Vol 27 (3) ◽  
pp. 533
Author(s):  
Raed Alzyoud ◽  
Zeyad Habahbeh ◽  
Mohammad Mutereen ◽  
Adel Wahadneh ◽  
Mohammad Abu-Shukair
Keyword(s):  
Common Variable Immunodeficiency ◽  
Single Center ◽  
Single Center Experience ◽  
Common Variable

Evaluation of cytokine genetic polymorphisms in adult patients with common variable immunodeficiency: A single-center study

2016 ◽  
Vol 176 ◽  
pp. 97-104 ◽  
Author(s):  
Dijana Perovic ◽  
Vladimir Perovic ◽  
Vera Pravica ◽  
Branka Bonaci-Nikolic ◽  
Radovan Mijanovic ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Common Variable Immunodeficiency ◽  
Adult Patients ◽  
Single Center ◽  
Single Center Study ◽  
Common Variable ◽  
Center Study

Lymphocyte Subgroups and KREC Numbers in Common Variable Immunodeficiency: A Single Center Study

2020 ◽  
Vol 40 (3) ◽  
pp. 494-502
Author(s):  
Ismail Yaz ◽  
Begum Ozbek ◽  
Yuk Yin Ng ◽  
Pinar Gur Cetinkaya ◽  
Sevil Oskay Halacli ◽  
...  
Keyword(s):  
Common Variable Immunodeficiency ◽  
Single Center ◽  
Single Center Study ◽  
Common Variable ◽  
Center Study

scholarly journals Adults with common variable immunodeficiency: a single-center experience*

2017 ◽  
Vol 47 ◽  
pp. 1-12 ◽  
Author(s):  
Uğur Haci MUŞABAK ◽  
Fevzi Sait DEMİREL YEŞİLLİK ◽  
Abdullah BAYSAN ◽  
Ali SELÇUK ◽  
Özgür KARTAL ◽  
...  
Keyword(s):  
Common Variable Immunodeficiency ◽  
Single Center ◽  
Single Center Experience ◽  
Common Variable

Common variable immunodeficiency disorders: division into distinct clinical phenotypes

Blood ◽  
2008 ◽  
Vol 112 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Helen Chapel ◽  
Mary Lucas ◽  
Martin Lee ◽  
Janne Bjorkander ◽  
David Webster ◽  
...  
Keyword(s):  
B Cells ◽  
Gaussian Distribution ◽  
Common Variable Immunodeficiency ◽  
Lymphocytic Infiltration ◽  
Lymphoid Malignancy ◽  
Survival Times ◽  
Clinical Phenotypes ◽  
Immunoglobulin Isotypes ◽  
Increased Risk ◽  
Common Variable

AbstractThe European Common Variable Immunodeficiency Disorders registry was started in 1996 to define distinct clinical phenotypes and determine overlap within individual patients. A total of 7 centers contributed patient data, resulting in the largest cohort yet reported. Patients (334), validated for the diagnosis, were followed for an average of 25.6 years (9461 patient-years). Data were used to define 5 distinct clinical phenotypes: no complications, autoimmunity, polyclonal lymphocytic infiltration, enteropathy, and lymphoid malignancy. A total of 83% of patients had only one of these phenotypes. Analysis of mortality showed a considerable reduction in the last 15 years and that different phenotypes were associated with different survival times. Types of complications and clinical phenotypes varied significantly between countries, indicating the need for large, international registries. Ages at onset of symptoms and diagnosis were shown to have a Gaussian distribution, but were not useful predictors of phenotype. The only clinical predictor was polyclonal lymphocytic infiltration, which was associated with a 5-fold increased risk of lymphoid malignancy. There was widespread variation in the levels of serum immunoglobulin isotypes as well as in the percentages and absolute numbers of B cells, confirming the heterogeneity of these conditions. Higher serum IgM and lower circulating CD8 proportions were found to be predictive markers for polyclonal lymphocytic infiltration and autoimmunity, respectively.

Common Variable Immunodeficiency (CVID) – variables humorales Immundefektsyndrom

Praxis ◽  
2007 ◽  
Vol 96 (1) ◽  
pp. 3-11
Author(s):  
Suter-Meyer ◽  
Nigg ◽  
Kolyvanos Naumann ◽  
Käser ◽  
Vetter
Keyword(s):  
Common Variable Immunodeficiency ◽  
Common Variable

A case of polyglandular autoimmune disease associated with common variable immunodeficiency

2015 ◽  
Author(s):  
Ishrat Khan ◽  
Mirena Noyvirt ◽  
Aicha Bouraoui ◽  
Penny Owen ◽  
Helen Lane
Keyword(s):  
Autoimmune Disease ◽  
Common Variable Immunodeficiency ◽  
Common Variable
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