Current treatment options in patients with mastocytosis: status in 2015 and future perspectives

2015 ◽  
Vol 94 (6) ◽  
pp. 474-490 ◽  
Author(s):  
Michel Arock ◽  
Cem Akin ◽  
Olivier Hermine ◽  
Peter Valent
Keyword(s):  
Treatment Options ◽  
Current Treatment ◽  
Future Perspectives

scholarly journals Progressive multifocal leukoencephalopathy: current treatment options and future perspectives

2015 ◽  
Vol 8 (6) ◽  
pp. 255-273 ◽  
Author(s):  
Dejan Pavlovic ◽  
Andriani C. Patera ◽  
Fredrik Nyberg ◽  
Marianne Gerber ◽  
Maggie Liu ◽  
...  
Keyword(s):  
Progressive Multifocal Leukoencephalopathy ◽  
Treatment Options ◽  
Current Treatment ◽  
Future Perspectives

Advanced Melanoma: Current Treatment Options, Biomarkers, and Future Perspectives

2017 ◽  
Vol 19 (3) ◽  
pp. 303-317 ◽  
Author(s):  
Elisa A. Rozeman ◽  
Tim J. A. Dekker ◽  
John B. A. G. Haanen ◽  
Christian U. Blank
Keyword(s):  
Treatment Options ◽  
Current Treatment ◽  
Advanced Melanoma ◽  
Future Perspectives

scholarly journals Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment

2021 ◽  
Author(s):  
Qiwei Yang ◽  
Michal Ciebiera ◽  
Maria Victoria Bariani ◽  
Mohamed Ali ◽  
Hoda Elkafas ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Treatment Options ◽  
Uterine Fibroids ◽  
Current Treatment ◽  
Future Perspectives ◽  
Invasive Treatment ◽  
Treatment Interventions ◽  
Comprehensive Review ◽  
Non Invasive

Abstract Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the most common tumors in women worldwide. To date, no long-term or non-invasive treatment option exists for hormone-dependent uterine fibroids due to the limited knowledge about the molecular mechanisms underlying the initiation and development of uterine fibroids. This paper comprehensively summarizes the recent research advances on uterine fibroids, focusing on their risk factors, development origin, pathogenetic mechanisms, and treatment options. Additionally, we describe the current treatment interventions for uterine fibroids. Finally, future perspectives on uterine fibroids studies are summarized. Deeper mechanistic insights into tumor etiology and uterine fibroids’ complexity can contribute to the newer targeted therapies.

scholarly journals Current Therapeutics and Future Perspectives to Ocular Melanocytic Neoplasms in Dogs and Cats

2021 ◽  
Vol 8 (12) ◽  
pp. 225
Author(s):  
Tarcísio Guerra Guimarães ◽  
Karla Menezes Cardoso ◽  
Pedro Tralhão ◽  
Carlos Miguel Marto ◽  
Nuno Alexandre ◽  
...  
Keyword(s):  
Visual Loss ◽  
Financial Constraints ◽  
Clinical Presentation ◽  
Treatment Options ◽  
Life Quality ◽  
Current Treatment ◽  
Therapeutic Strategies ◽  
Future Perspectives ◽  
Variable Response ◽  
Benign Lesions

Neoplasms of melanocytic origin are diseases relevant to dogs and cats’ ophthalmic oncology due to their incidence, potential visual loss, and consequent decrease in life quality and expectancy. Despite its non-specific clinical presentation, melanocytic neoplasms can be histologically distinguished in melanocytomas, which present benign characteristics, and malignant melanomas. The diagnosis often occurs in advanced cases, limiting the therapeutic options. Surgery, cryotherapy, radiotherapy, photodynamic therapy (PDT), and laser are currently available therapeutic strategies. As no clinical guidelines are available, the treatment choice is primarily based on the clinician’s preference, proficiency, and the owner’s financial constraints. While surgery is curative in benign lesions, ocular melanomas present a variable response to treatments, besides the potential of tumour recurrences or metastatic disease. This review presents the currently available therapies for ocular melanocytic neoplasms in dogs and cats, describing the therapeutic, indications, and limitations. Additionally, new therapeutics being developed are presented and discussed, as they can improve the current treatment options.

An Overview of Dementias

2012 ◽  
Vol 21 (3) ◽  
pp. 75-84
Author(s):  
Venkata Vijaya K. Dalai ◽  
Jason E. Childress ◽  
Paul E Schulz
Keyword(s):  
Clinical Presentation ◽  
Treatment Options ◽  
Current Treatment ◽  
Great Variability ◽  
Health Concern ◽  
Public Health Concern ◽  
Life Threatening ◽  
The Common ◽  
Neurodegenerative Dementias ◽  
Made In

Dementia is a major public health concern that afflicts an estimated 24.3 million people worldwide. Great strides are being made in order to better diagnose, prevent, and treat these disorders. Dementia is associated with multiple complications, some of which can be life-threatening, such as dysphagia. There is great variability between dementias in terms of when dysphagia and other swallowing disorders occur. In order to prepare the reader for the other articles in this publication discussing swallowing issues in depth, the authors of this article will provide a brief overview of the prevalence, risk factors, pathogenesis, clinical presentation, diagnosis, current treatment options, and implications for eating for the common forms of neurodegenerative dementias.

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