Immunosuppressive agents in the treatment of inhibitors in congenital haemophilia A and B - a systematic literature review

2014 ◽  
Vol 93 ◽  
pp. 26-38 ◽  
Author(s):  
Britta Antonia Petra Laros-van Gorkom ◽  
Céline Falaise ◽  
Jan Astermark
Haemophilia ◽  
2019 ◽  
Vol 25 (5) ◽  
pp. 755-763 ◽  
Author(s):  
Flora Peyvandi ◽  
Fatemeh Tavakkoli ◽  
Diana Frame ◽  
Jennifer Quinn ◽  
Benjamin Kim ◽  
...  

RMD Open ◽  
2019 ◽  
Vol 5 (2) ◽  
pp. e001035 ◽  
Author(s):  
Christien Rondaan ◽  
Victoria Furer ◽  
Marloes W Heijstek ◽  
Nancy Agmon-Levin ◽  
Marc Bijl ◽  
...  

AimTo present a systematic literature review (SLR) on efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD), aiming to provide a basis for updating the EULAR evidence-based recommendations.MethodsAn SLR was performed according to the standard operating procedures for EULAR-endorsed recommendations. Outcome was determined by efficacy, immunogenicity and safety of vaccination in adult patients with AIIRD, including those receiving immunomodulating therapy. Furthermore, a search was performed on the effect of vaccinating household members of patients with AIIRD on the occurrence of vaccine-preventable infections in patients and their household members (including newborns). The literature search was performed using Medline, Embase and the Cochrane Library (October 2009 to August 2018).ResultsWhile most investigated vaccines were efficacious and/or immunogenic in patients with AIIRD, some were less efficacious than in healthy control subjects, and/or in patients receiving immunosuppressive agents. Adverse events of vaccination were generally mild and the rates were comparable to those in healthy persons. Vaccination did not seem to lead to an increase in activity of the underlying AIIRD, but insufficient power of most studies precluded arriving at definite conclusions. The number of studies investigating clinical efficacy of vaccination is still limited. No studies on the effect of vaccinating household members of patients with AIIRD were retrieved.ConclusionEvidence on efficacy, immunogenicity and safety of vaccination in patients with AIIRD was systematically reviewed to provide a basis for updated recommendations.


Haemophilia ◽  
2021 ◽  
Vol 27 (2) ◽  
pp. 199-210
Author(s):  
Natacha Dewarrat ◽  
Mathilde Gavillet ◽  
Anne Angelillo‐Scherrer ◽  
Olaia Naveiras ◽  
Francesco Grandoni ◽  
...  

2014 ◽  
Author(s):  
Heather T. Snyder ◽  
Maggie R. Boyle ◽  
Lacey Gosnell ◽  
Julia A. Hammond ◽  
Haley Huey

2018 ◽  
Vol 19 (4) ◽  
pp. 600-611 ◽  
Author(s):  
Nathan Beel ◽  
Carla Jeffries ◽  
Charlotte Brownlow ◽  
Sonya Winterbotham ◽  
Jan du Preez

Sign in / Sign up

Export Citation Format

Share Document