scholarly journals ReMindCare , an app for daily clinical practice in patients with first episode psychosis: A pragmatic real‐world study protocol

2020 ◽  
Author(s):  
Lucia Bonet ◽  
John Torous ◽  
David Arce ◽  
Ignacio Blanquer ◽  
Julio Sanjuán
Keyword(s):  
Clinical Practice ◽  
Study Protocol ◽  
Real World ◽  
First Episode Psychosis ◽  
Daily Clinical Practice ◽  
First Episode ◽  
Episode Psychosis

scholarly journals Time for a change of practice: the real-world value of testing for neuronal autoantibodies in acute first-episode psychosis

BJPsych Open ◽  
2018 ◽  
Vol 4 (4) ◽  
pp. 262-264 ◽  
Author(s):  
Thomas A. Pollak ◽  
Belinda R. Lennox
Keyword(s):  
Lumbar Puncture ◽  
Real World ◽  
Culture Change ◽  
Autoimmune Encephalitis ◽  
First Episode Psychosis ◽  
Acute Onset ◽  
First Episode ◽  
The Real ◽  
Episode Psychosis ◽  
Neuronal Autoantibodies

SummaryIt is time that all patients with acute-onset psychosis are screened for autoimmune encephalitis, that lumbar puncture becomes a routine psychiatric investigation and that immunotherapy is available in indicated cases. We call for a culture change in the management of psychosis by psychiatry.Declaration of interestNone.

scholarly journals A comparison of neurocognition and functioning in first episode psychosis populations: do research samples reflect the real world?

2018 ◽  
Vol 54 (3) ◽  
pp. 291-301 ◽  
Author(s):  
Emily Kline ◽  
Victoria Hendel ◽  
Michelle Friedman-Yakoobian ◽  
Raquelle I. Mesholam-Gately ◽  
Ann Findeisen ◽  
...  
Keyword(s):  
Real World ◽  
First Episode Psychosis ◽  
First Episode ◽  
The Real ◽  
Episode Psychosis

First-episode psychosis: What does it mean?

2016 ◽  
Vol 33 (S1) ◽  
pp. s258-s258
Author(s):  
S. Marques ◽  
F. Godinho ◽  
A.L. Melo ◽  
D. Barrocas
Keyword(s):  
Real World ◽  
Negative Symptoms ◽  
First Episode Psychosis ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Real World Setting ◽  
Episode Psychosis ◽  
Competing Interest ◽  
Disorganized Speech ◽  
Psychotic Features

IntroductionFirst-Episode Psychosis (FEP) is a variable condition, characterized by the emergence of new psychotic features for a period of at least 1 week. The majority of existing studies about FEP only address schizophrenia spectrum psychosis (SSP), which may limit the capacity to fully characterize this entity.Objectives/AimsReport the clinical and socio-demographic characteristics of patients with FEP in real-world setting, and compare the differences among SSP and affective FEP.MethodsRetrospective analysis of clinical files of patients admitted to our hospital unit with FEP diagnosis from January/2012 to April/2015. Clinician-rated dimensions of psychosis symptom severity scales (DSM-5) were applied.ResultsAnnual incidence of FEP was 11,3/100,000. From a total of 755 patients, 57 (7,5%) corresponded to FEP; 38 (66,7%) were diagnosed with SSP, 11 (19,3%) affective psychosis, 3 (5,2%) toxic psychosis and 5 (8,8%) organic psychosis. Most were female (61,4%), with a mean age of 49 years. The majority were unemployed (66,7%), lived with family (57,9%), and presented with moderate-severe delusions (80,1%), but without hallucinations (57,8%), disorganized speech (59,6%) or negative symptoms (85,9%). Affective FEP patients were older (61 vs 45 years), presented with less severe psychotic symptoms (7,2 vs 8,3 points), but with higher hospital admission (26,1 vs 21,1 days).ConclusionsRegardless the growing interest concerning FEP, its conceptualization and characterization remains controversial. Our results differ from pre-existing literature data, especially concerning gender and age. By including all the possible etiologies of FEP, we aimed to obtain a more realistic characterization of this entity in a real-world setting.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Investigating the impact of HIV on patients with first episode psychosis: a study protocol for a longitudinal cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e046593
Author(s):  
Usha Chhagan ◽  
Vuyokazi Ntlantsana ◽  
Andrew Tomita ◽  
Thirusha Naidu ◽  
Bonginkosi Chiliza ◽  
...  
Keyword(s):  
Substance Use ◽  
Study Protocol ◽  
First Episode Psychosis ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Control Group ◽  
People Living With Hiv ◽  
Neuropsychiatric Complications ◽  
Episode Psychosis ◽  
The Impact

IntroductionSouth Africa (SA) has a high HIV prevalence and limited mental healthcare resources. Neuropsychiatric complications such as psychosis onset in people living with HIV (PLWHIV) remains poorly understood. The study aims to compare the socio-demographic, clinical, substance use, cognitive and trauma profile of PLWHIV presenting with first episode psychosis (FEP) to those with the condition but without HIV.Methods and analysisThis study will compare presentation, course, and outcome of a cohort of PLWHIV and FEP with a control group recruited over a 3-year period. We will prospectively test the hypothesis that the 2 groups are socio-demographically, clinically and cognitively distinct at illness presentation, with higher trauma burden and poorer outcomes in those with the dual burden of HIV and FEP. FEP participants, confirmed by a structured neuropsychiatric interview, will have their socio-demographic, psychosis, mood, motor, trauma and substance use variables assessed. A neuropsychological battery will be completed to assess cognition, while quality of life, psychotic symptoms and HIV markers will be measured at 3, 6 and 12 months.Ethics and disseminationThe study protocol has been reviewed and ethics approval obtained from the Biomedical Research Ethics Committee (BC 571/18) of the University of KwaZulu-Natal. The results from this investigation will be actively disseminated through peer-reviewed journal publications and conference presentations.

Pathways to Care and Patterns of Care in First Episode Psychosis Patients Treated in Community Based-mental Health Services. A 5-Years Follow-up from the PICOS

2017 ◽  
Vol 41 (S1) ◽  
pp. S160-S160
Author(s):  
E. Miglietta ◽  
A. Lasalvia ◽  
C. Comacchio ◽  
D. Cristofalo ◽  
C. Bonetto ◽  
...  
Keyword(s):  
Mental Health ◽  
Clinical Practice ◽  
Mental Health Services ◽  
Health Services ◽  
First Episode Psychosis ◽  
First Episode ◽  
Community Based ◽  
Episode Psychosis ◽  
Pathway To Care

IntroductionInternational treatment guidelines recommend that key elements to reduce the burden of psychosis are the early identification of people and the adoption of specific evidence based interventions.ObjectivesTo investigate the pathway to care and patterns of interventions provided by community based-mental health services (CMHS) to a cohort of first-episode psychosis (FEP) patients over 5-years period, exploring in which degree guidelines are met in routine clinical practice.MethodsStudy conducted in the context of the Psychosis Incident Cohort Outcome Study (PICOS), a multisite naturalistic research conducted in the Veneto Region (Italy) on FEP patients in a 4.6 million inhabitants catchment area. A comprehensive set of standardized measures was used, including ad hoc schedules to collect information on referrals to psychiatric services and on pharmacological and psycho-social treatments according to a multiwave follow-up design (1-, 2- and 5 years).ResultsThree hundred and ninety-seven FEP patients were assessed at BL, 286 at 1 year, 233 at 2 years and 205 at 5 years. 47.4% of patients were helped to seek care by a relative and more than one half entered the treatment route through an emergency access. Regarding the interventions received, 96% of patients had been prescribed neuroleptics and atypical were the most prescribed class (66.9%). Only half received a psychosocial intervention during the first year and this percentage progressively decreased at each FU.DiscussionFindings highlight discrepancies between interventions provided by CMHS and the best treatment options recommended by guidelines, suggesting the need to implement specific initiatives aiming to close the gap between research and clinical practice.

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