Relation between premorbid adjustment, duration of untreated psychosis and close interpersonal trauma in first-episode psychosis

2016 ◽  
Vol 12 (3) ◽  
pp. 316-323 ◽  
Author(s):  
Ulrik Helt Haahr ◽  
Tor Ketil Larsen ◽  
Erik Simonsen ◽  
Bjørn Rishovd Rund ◽  
Inge Joa ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
Interpersonal Trauma ◽  
First Episode ◽  
Duration Of Untreated Psychosis ◽  
Premorbid Adjustment ◽  
Episode Psychosis

scholarly journals Premorbid adjustment in first-episode non-affective psychosis: Distinct patterns of pre-onset course

2004 ◽  
Vol 185 (2) ◽  
pp. 108-115 ◽  
Author(s):  
Tor K. Larsen ◽  
Svein Friis ◽  
Ulrik Haahr ◽  
Jan Olav Johannessen ◽  
Ingrid Melle ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Negative Symptoms ◽  
First Episode Psychosis ◽  
First Episode ◽  
Duration Of Untreated Psychosis ◽  
Affective Psychosis ◽  
Premorbid Adjustment ◽  
Episode Psychosis ◽  
Premorbid Functioning ◽  
Shed Light

BackgroundKnowledge about premorbid development in psychosis can shed light upon theories about aetiology and schizophrenic heterogeneity, and form a basis for early detection initiatives.AimsTo identify and validate patterns of premorbid functioning in first-episode psychosis.MethodThe Premorbid Adjustment Scale was used to examine 335 patients.ResultsSocial and academic function constituted fairly independent dimensions. Cluster analysis identified groups varying both in level and course. Patients with a stable social course compared with a deteriorating one had a shorter duration of untreated psychosis, were older, had more friends and less negative symptoms. Good childhood academic function correlated with more education, more meaningful activities and better working memory. Patients with a stable academic course were older at admission.ConclusionsPatterns of premorbid development suggest both neuro-developmental and neuroregressive pathways to illness.

Retrospective study of first episode psychosis in the Dublin Southwest Mental Health Service: demographics, clinical profile and service evaluation of treatment

2017 ◽  
Vol 36 (4) ◽  
pp. 249-258 ◽  
Author(s):  
A.-M. Clarke ◽  
P. McLaughlin ◽  
J. Staunton ◽  
K. Kerins ◽  
B. Power ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Service ◽  
Family Intervention ◽  
First Episode Psychosis ◽  
First Episode ◽  
Psychological Interventions ◽  
Duration Of Untreated Psychosis ◽  
Episode Psychosis ◽  
Baseline Information ◽  
Healthcare Monitoring

ObjectiveIn Ireland, National Clinical Programmes are being established to improve and standardise patient care throughout the Health Service Executive. In line with internationally recognised guidelines on the treatment of first episode psychosis the Early Intervention in Psychosis (EIP) programme is being drafted with a view to implementation by mental health services across the country. We undertook a review of patients presenting with a first episode of psychosis to the Dublin Southwest Mental Health Service before the implementation of the EIP. This baseline information will be used to measure the efficacy of our EIP programme.MethodsPatients who presented with a first episode psychosis were retrospectively identified through case note reviews and consultation with treating teams. We gathered demographic and clinical information from patients as well as data on treatment provision over a 2-year period from the time of first presentation. Data included age at first presentation, duration of untreated psychosis, diagnosis, referral source, antipsychotic prescribing rates and dosing, rates of provision of psychological interventions and standards of physical healthcare monitoring. Outcome measures with regards to rates of admission over a 2-year period following initial presentation were also recorded.ResultsIn total, 66 cases were identified. The majority were male, single, unemployed and living with their family or spouse. The mean age at first presentation was 31 years with a mean duration of untreated psychosis of 17 months. Just under one-third were diagnosed with schizophrenia. Approximately half of the patients had no contact with a health service before presentation. The majority of patients presented through the emergency department. Two-thirds of all patients had a hospital admission within 2 years of presentation and almost one quarter of patients had an involuntary admission. The majority of patients were prescribed antipsychotic doses within recommended British National Formulary guidelines. Most patients received individual support through their keyworker and family intervention was provided in the majority of cases. Only a small number received formal Cognitive-Behavioural Therapy. Physical healthcare monitoring was insufficiently recorded in the majority of patients.ConclusionsThere is a shortage of information on the profile and treatment of patients presenting with a first episode of psychosis in Ireland. This baseline information is important in evaluating the efficacy of any new programme for this patient group. Many aspects of good practice were identified within the service in particular with regards to the appropriate prescribing of antipsychotic medication and the rates of family intervention. Deficiencies remain however in the monitoring of physical health and the provision of formal psychological interventions to patients. With the implementation of an EIP programme it is hoped that service provision would improve nationwide and to internationally recognised standards.

Duration of untreated psychosis and neuropsychological function in first episode psychosis

2007 ◽  
Vol 95 (1-3) ◽  
pp. 103-110 ◽  
Author(s):  
Julia M. Lappin ◽  
Kevin D. Morgan ◽  
Craig Morgan ◽  
Paola Dazzan ◽  
Abraham Reichenberg ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Neuropsychological Function ◽  
Duration Of Untreated Psychosis ◽  
Episode Psychosis
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