scholarly journals Oxidized phospholipids and lipoprotein(a): An update

2021 ◽  
Author(s):  
Amalia Despoina Koutsogianni ◽  
Evangelos Liberopoulos ◽  
Konstantinos Tellis ◽  
Alexandros D. Tselepis
Keyword(s):  
Oxidized Phospholipids ◽  
Lipoprotein A

scholarly journals Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet

2010 ◽  
Vol 51 (11) ◽  
pp. 3324-3330 ◽  
Author(s):  
Nastaran Faghihnia ◽  
Sotirios Tsimikas ◽  
Elizabeth R. Miller ◽  
Joseph L. Witztum ◽  
Ronald M. Krauss
Keyword(s):  
High Carbohydrate Diet ◽  
Oxidized Phospholipids ◽  
Low Fat ◽  
Carbohydrate Diet ◽  
Lipoprotein A ◽  
High Carbohydrate

Lipoprotein(A), Oxidized Phospholipids, And Aortic Valve Microcalcification Assessed By 18f-Naf Pet/Ct

2019 ◽  
Vol 287 ◽  
pp. e110-e111
Author(s):  
A.A. Després ◽  
N. Perrot ◽  
L. Tastet ◽  
A. Pouliot ◽  
M. Shen ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Oxidized Phospholipids ◽  
Lipoprotein A ◽  
Pet Ct

scholarly journals Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

Circulation ◽  
2016 ◽  
Vol 134 (8) ◽  
pp. 611-624 ◽  
Author(s):  
Fleur M. van der Valk ◽  
Siroon Bekkering ◽  
Jeffrey Kroon ◽  
Calvin Yeang ◽  
Jan Van den Bossche ◽  
...  
Keyword(s):  
Arterial Wall ◽  
Oxidized Phospholipids ◽  
Lipoprotein A ◽  
Inflammatory Monocyte

Abstract 235: Prevalence of Lipoprotein(a) Measurements and Extent of Lipoprotein(a) Elevations in 2,266 Patients with Aortic Stenosis: Results from an Academic Echocardiography Laboratory Practice Setting

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Michael J Wilkinson ◽  
Gary S Ma ◽  
Calvin Yeang ◽  
Monet Strachan ◽  
Joel Wilson ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Practice Setting ◽  
Oxidized Phospholipids ◽  
Laboratory Practice ◽  
Lipoprotein A ◽  
Causal Risk Factor ◽  
Number Of Patients ◽  
Echocardiography Laboratory ◽  
Ongoing Development ◽  
The University

Background: The LPA gene causes elevated lipoprotein(a) (Lp(a)) levels and causally mediates calcific aortic valve stenosis (AS). Elevated Lp(a) and its associated oxidized phospholipids (OxPL-apoB) predict the progression of pre-existing AS and need for aortic valve replacement and are targets of therapy. Methods: We determined the prevalence and the extent of Lp(a) elevation in patients with AS diagnosed by echocardiography performed at the University of California San Diego between 2010-2015. Severity of AS was classified as critical, severe, moderate, mild, or trace. Lp(a) levels were organized as Lp(a) <30 mg/dL, 30-50 mg/dL, 50-100 mg/dL and >100 mg/dL. Results: 2,266 patients with AS were found, with 130 critical, 333 severe, 477 moderate, 1318 mild, and 8 cases of trace AS. Mean age was 75.0 and range 18-106 years. 51% of patients were male. Prevalence of any Lp(a) measurement was 159/2,266 patients (7.02%). The number (%) of patients with an Lp(a) level was: 1) critical (n=4, 3.1%), 2) severe (n=28, 8.4%), 3) moderate (n=56, 11.7%), 4) mild (n=71, 5.4%), and 5) trace (n=0). The extent of Lp(a) elevation within each AS category is in Table 1: 55/159 (34%), 35/159 (22%) and 19/159 (12%) of patients had Lp(a) >30 mg/dL, >50 mg/dL and >100 mg/dL, respectively. Conclusion: Lp(a) was measured in only 7.0% of patients with AS in an academic setting. Given the ongoing development of therapies to lower Lp(a) in patients with AS, educational efforts are needed to raise awareness of Lp(a) as a causal risk factor for AS.

Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a)

2016 ◽  
Vol 10 (3) ◽  
pp. 594-603 ◽  
Author(s):  
Calvin Yeang ◽  
Ming-Yow Hung ◽  
Young-Sup Byun ◽  
Paul Clopton ◽  
Xiaohong Yang ◽  
...  
Keyword(s):  
Therapeutic Interventions ◽  
Oxidized Phospholipids ◽  
Lipoprotein A ◽  
Apolipoprotein B100

scholarly journals Oxidized Phospholipids, Lipoprotein(a), Lipoprotein-Associated Phospholipase A2 Activity, and 10-Year Cardiovascular Outcomes

2007 ◽  
Vol 27 (8) ◽  
pp. 1788-1795 ◽  
Author(s):  
Stefan Kiechl ◽  
Johann Willeit ◽  
Manuel Mayr ◽  
Brigitte Viehweider ◽  
Martin Oberhollenzer ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Cardiovascular Outcomes ◽  
Oxidized Phospholipids ◽  
Lipoprotein A ◽  
Phospholipase A2 Activity

scholarly journals Lipoprotein(a) and oxidized phospholipids in calcific aortic valve stenosis

2016 ◽  
Vol 31 (4) ◽  
pp. 440-450 ◽  
Author(s):  
Calvin Yeang ◽  
Michael J. Wilkinson ◽  
Sotirios Tsimikas
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Oxidized Phospholipids ◽  
Lipoprotein A
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