An under‐recognized phenomenon: Myocardial volume change during the cardiac cycle

2021 ◽  
Author(s):  
Vinayak Kumar ◽  
Armando Manduca ◽  
Chaitanya Rao ◽  
Alexander J. Ryu ◽  
Raymond J. Gibbons ◽  
...  
Keyword(s):  
Volume Change ◽  
Cardiac Cycle

Myocardial volume change during cardiac cycle derived from three orthogonal systolic strains: towards a quality assessment of strains

2018 ◽  
Vol 60 (3) ◽  
pp. 286-292 ◽  
Author(s):  
Laurent Bonnemains ◽  
Anne Sophie Guerard ◽  
Paul Soulié ◽  
Freddy Odille ◽  
Jacques Felblinger
Keyword(s):  
Left Ventricle ◽  
Quality Assessment ◽  
Healthy Volunteers ◽  
Volume Change ◽  
Cardiac Cycle ◽  
Mean Value ◽  
Left Ventricular ◽  
Strain Measurements ◽  
Significant Difference ◽  
Standard Deviations

Background The relative modification of the myocardial volume between end-systole and end-diastole ([Formula: see text]) has already been assessed with different methods and falls in a range of 0.9–0.97 (mean value = 0.93). Purpose To estimate [Formula: see text] from the three longitudinal ([Formula: see text], circumferential ([Formula: see text]), and radial ([Formula: see text]) strains of the left ventricle using the formula: [Formula: see text] and to test whether this estimate of [Formula: see text] can be used as a marker of the echocardiography quality. Material and Methods Two hundred manuscripts, including a total of 34,690 patients or healthy volunteers, were identified in the Medline database containing values of [Formula: see text], [Formula: see text], and [Formula: see text] measured from echocardiography. Results The median value of was 0.93, in accordance with the literature, with no significant difference between patients or healthy volunteers ( P = 0.38). The proportion of studies with [Formula: see text] was 79%. When only considering groups of healthy volunteers, the studies failing this test had higher standard deviations for the three individual strains: 0.038 vs. 0.029 ( P = 0.02) for [Formula: see text]; 0.060 vs. 0.034 ( P < 10–6) for [Formula: see text], and 0.243 vs. 0.101 ( P < 10–14) for [Formula: see text]. Conclusion The median ratio of the left ventricular myocardial volumes between end-systole and end-diastole in the investigated studies was [Formula: see text]. The formula [Formula: see text] could be used to detect studies with inaccurate strain measurements.

scholarly journals Changes in regional myocardial volume during the cardiac cycle: implications for transmural blood flow and cardiac structure

2008 ◽  
Vol 295 (2) ◽  
pp. H610-H618 ◽  
Author(s):  
Hiroshi Ashikaga ◽  
Benjamin A. Coppola ◽  
Katrina G. Yamazaki ◽  
Francisco J. Villarreal ◽  
Jeffrey H. Omens ◽  
...  
Keyword(s):  
Blood Flow ◽  
Volume Change ◽  
Time Course ◽  
Cardiac Cycle ◽  
Left Ventricular ◽  
Atrial Pacing ◽  
Canine Heart ◽  
Spatiotemporal Resolution ◽  
Tissue Pressure

Although previous studies report a reduction in myocardial volume during systole, myocardial volume changes during the cardiac cycle have not been quantitatively analyzed with high spatiotemporal resolution. We studied the time course of myocardial volume in the anterior mid-left ventricular (LV) wall of normal canine heart in vivo ( n = 14) during atrial or LV pacing using transmurally implanted markers and biplane cineradiography (8 ms/frame). During atrial pacing, there was a significant transmural gradient in maximum volume decrease (4.1, 6.8, and 10.3% at subepi, midwall, and subendo layer, respectively, P = 0.002). The rate of myocardial volume increase during diastole was 4.7 ± 5.8, 6.8 ± 6.1, and 10.8 ± 7.7 ml·min−1·g−1, respectively, which is substantially larger than the average myocardial blood flow in the literature measured by the microsphere method (0.7–1.3 ml·min−1·g−1). In the early activated region during LV pacing, myocardial volume began to decrease before the LV pressure upstroke. We conclude that the volume change is greater than would be estimated from the known average transmural blood flow. This implies the existence of blood-filled spaces within the myocardium, which could communicate with the ventricular lumen. Our data in the early activated region also suggest that myocardial volume change is caused not by the intramyocardial tissue pressure but by direct impingement of the contracting myocytes on the microvasculature.

scholarly journals Cardiac Cycle-Related Volume Change in Unruptured Cerebral Aneurysms

Stroke ◽  
2012 ◽  
Vol 43 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Junko Kuroda ◽  
Manabu Kinoshita ◽  
Hisashi Tanaka ◽  
Takeo Nishida ◽  
Hajime Nakamura ◽  
...  
Keyword(s):  
Volume Change ◽  
Cardiac Cycle ◽  
Cerebral Aneurysms ◽  
Unruptured Cerebral Aneurysms

scholarly journals Magnetic resonance imaging–based measures predictive of short-term surgical outcome in patients with Chiari malformation Type I: a pilot study

2017 ◽  
Vol 26 (1) ◽  
pp. 28-38 ◽  
Author(s):  
Noam Alperin ◽  
James Ryan Loftus ◽  
Ahmet M. Bagci ◽  
Sang H. Lee ◽  
Carlos J. Oliu ◽  
...  
Keyword(s):  
Volume Change ◽  
Chiari Malformation ◽  
Cardiac Cycle ◽  
Venous Drainage ◽  
Chief Complaint ◽  
Favorable Outcome ◽  
Type I ◽  
Intracranial Volume ◽  
Predictors Of Outcome ◽  
Chiari Malformation Type I

OBJECTIVE This study identifies quantitative imaging-based measures in patients with Chiari malformation Type I (CM-I) that are associated with positive outcomes after suboccipital decompression with duraplasty. METHODS Fifteen patients in whom CM-I was newly diagnosed underwent MRI preoperatively and 3 months postoperatively. More than 20 previously described morphological and physiological parameters were derived to assess quantitatively the impact of surgery. Postsurgical clinical outcomes were assessed in 2 ways, based on resolution of the patient's chief complaint and using a modified Chicago Chiari Outcome Scale (CCOS). Statistical analyses were performed to identify measures that were different between the unfavorable- and favorable-outcome cohorts. Multivariate analysis was used to identify the strongest predictors of outcome. RESULTS The strongest physiological parameter predictive of outcome was the preoperative maximal cord displacement in the upper cervical region during the cardiac cycle, which was significantly larger in the favorable-outcome subcohorts for both outcome types (p < 0.05). Several hydrodynamic measures revealed significantly larger preoperative-to-postoperative changes in the favorable-outcome subcohort. Predictor sets for the chief-complaint classification included the cord displacement, percent venous drainage through the jugular veins, and normalized cerebral blood flow with 93.3% accuracy. Maximal cord displacement combined with intracranial volume change predicted outcome based on the modified CCOS classification with similar accuracy. CONCLUSIONS Tested physiological measures were stronger predictors of outcome than the morphological measures in patients with CM-I. Maximal cord displacement and intracranial volume change during the cardiac cycle together with a measure that reflects the cerebral venous drainage pathway emerged as likely predictors of decompression outcome in patients with CM-I.

Ocular Volume Change per Cardiac Cycle

2002 ◽  
Vol 34 (2) ◽  
pp. 94-96
Author(s):  
William Gee ◽  
James F. Reed III ◽  
Kenneth M. McDonald ◽  
Alice E. Madden
Keyword(s):  
Volume Change ◽  
Cardiac Cycle

Artifacts caused by dehydration and epoxy embedding in TEM

1991 ◽  
Vol 49 ◽  
pp. 338-339
Author(s):  
Hilton H. Mollenhauer
Keyword(s):  
Electron Microscopy ◽  
Electron Beam ◽  
Volume Change ◽  
Tissue Damage ◽  
Beam Specimen ◽  
Chemical Fixation ◽  
Resin Impregnation ◽  
Storage Vesicles ◽  
A Cell ◽  
Tissue Shrinkage

Various means have been devised to preserve biological specimens for electron microscopy, the most common being chemical fixation followed by dehydration and resin impregnation. It is intuitive, and has been amply demonstrated, that these manipulations lead to aberrations of many tissue elements. This report deals with three parts of this problem: specimen dehydration, epoxy embedding resins, and electron beam-specimen interactions. However, because of limited space, only a few points can be summarized.Dehydration: Tissue damage, or at least some molecular transitions within the tissue, must occur during passage of a cell or tissue to a nonaqueous state. Most obvious, perhaps, is a loss of lipid, both that which is in the form of storage vesicles and that associated with tissue elements, particularly membranes. Loss of water during dehydration may also lead to tissue shrinkage of 5-70% (volume change) depending on the tissue and dehydrating agent.

Short-term volume and turgor regulation in yeast

2008 ◽  
Vol 45 ◽  
pp. 147-160 ◽  
Author(s):  
Jörg Schaber ◽  
Edda Klipp
Keyword(s):  
Dynamic Model ◽  
Volume Change ◽  
Volume Regulation ◽  
Time Course ◽  
Osmotic Shock ◽  
Intracellular Concentration ◽  
Short Term ◽  
Hydrodynamic Property ◽  
Turgor Regulation ◽  
Thermodynamic Framework

Volume is a highly regulated property of cells, because it critically affects intracellular concentration. In the present chapter, we focus on the short-term volume regulation in yeast as a consequence of a shift in extracellular osmotic conditions. We review a basic thermodynamic framework to model volume and solute flows. In addition, we try to select a model for turgor, which is an important hydrodynamic property, especially in walled cells. Finally, we demonstrate the validity of the presented approach by fitting the dynamic model to a time course of volume change upon osmotic shock in yeast.

FREE VOLUME CHANGE OF METALLIC GLASSES STUDIED BY THERMAL EXPANSION MEASUREMENTS

1980 ◽  
Vol 41 (C8) ◽  
pp. C8-875-C8-877
Author(s):  
E. Girt ◽  
P. Tomić ◽  
A. Kuršumović ◽  
T. Mihać-Kosanović
Keyword(s):  
Thermal Expansion ◽  
Free Volume ◽  
Volume Change ◽  
Metallic Glasses

Assessment of Myocardial Viability in Persistent Defects on Thallium-201 SPECT after Reinjection Using Gradient-Echo MRI

1996 ◽  
Vol 35 (05) ◽  
pp. 146-152 ◽  
Author(s):  
A. Kögler ◽  
H.-A. Schmitt ◽  
D. Emrich ◽  
H. Kreuzer ◽  
D. L. Munz ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Myocardial Viability ◽  
Cardiac Cycle ◽  
Single Photon ◽  
Contractile Function ◽  
Left Ventricular ◽  
Wall Thickening ◽  
Gradient Echo ◽  
Systolic Wall Thickening

SummaryThis prospective study assessed myocardial viability in 30 patients with coronary heart disease and persistent defects despite reinjection on TI-201 single-photon computed tomography (SPECT). In each patient, three observers graded TI-201 uptake in 7 left ventricular wall segments. Gradient-echo magnetic resonance imaging in the region of the persistent defect generated 12 to 16 short axis views representing a cardiac cycle. A total of 120 segments were analyzed. Mean end-diastolic wall thickness and systolic wall thickening (± SD) was 11.5 ± 2.7 mm and 5.8 ± 3.9 mm in 48 segments with normal TI-201 uptake, 10.1 ± 3.4 mm and 3.7 ± 3.1 mm in 31 with reversible lesions, 11.3 ± 2.8 mm and 3.3 ± 1.9 mm in 10 with mild persistent defects, 9.2 ± 2.9 mm and 3.2 ±2.2 mm in 15 with moderate persistent defects, 5.8 ± 1.7 mm and 1.3 ± 1.4 mm in 16 with severe persistent defects, respectively. Significant differences in mean end-diastolic wall thickness (p <0.0005) and systolic wall thickening (p <0.005) were found only between segments with severe persistent defects and all other groups, but not among the other groups. On follow-up in 11 patients after revascularization, 6 segments with mild-to-moderate persistent defects showed improvement in mean systolic wall thickening that was not seen in 6 other segments with severe persistent defects. These data indicate that most myocardial segments with mild and moderate persistent TI-201 defects after reinjection still contain viable tissue. Segments with severe persistent defects, however, represent predominantly nonviable myocardium without contractile function.

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