Refined 4-group classification of left ventricular hypertrophy based on ventricular concentricity and volume dilatation outlines distinct noninvasive hemodynamic profiles in a large contemporary echocardiographic population

2018 ◽  
Vol 35 (9) ◽  
pp. 1258-1265 ◽  
Author(s):  
Andrea Barbieri ◽  
Andrea Rossi ◽  
Nicola Gaibazzi ◽  
Andrea Erlicher ◽  
Gian Francesco Mureddu ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Group Classification ◽  
Volume Dilatation

scholarly journals A 4-Tiered Classification of Left Ventricular Hypertrophy Based on Left Ventricular Geometry

2010 ◽  
Vol 3 (2) ◽  
pp. 164-171 ◽  
Author(s):  
Michel G. Khouri ◽  
Ronald M. Peshock ◽  
Colby R. Ayers ◽  
James A. de Lemos ◽  
Mark H. Drazner
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry

scholarly journals Exercise-induced cardiac remodeling in non-elite endurance athletes: Comparison of 2-tiered and 4-tiered classification of left ventricular hypertrophy

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0193203 ◽  
Author(s):  
Lukas D. Trachsel ◽  
Christoph P. Ryffel ◽  
Stefano De Marchi ◽  
Christian Seiler ◽  
Nicolas Brugger ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Cardiac Remodeling ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Exercise Induced

scholarly journals THE EFFECT OF DEGREE AND TYPE OF LEFT VENTRICULAR HYPERTROPHY ON VENTRICULAR ARRHYTHMIAS IN HYPERTENSION

2017 ◽  
pp. 027
Author(s):  
Ivan S. Tasić ◽  
Dragan Djordjević ◽  
Svetlana Kostić
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Ventricular Arrhythmias ◽  
Ventricular Hypertrophy ◽  
Systolic Dysfunction ◽  
Univariate Analysis ◽  
Holter Monitoring ◽  
Left Ventricular ◽  
Interval Dispersion

Finding the arrythmogenic potential in patients with arterial hypertension as well as its correlation with left ventricular hypertrophy (LVH), and its type and degree. The research included 109 hypertensive patients (pts) (54 male and 55 female), 54.2 ± 7.9 years old  without symptomatic coronary disease, myocardial infarction and  systolic dysfunction. All the pts had a clinical examination, ECG, 24 h Holter monitoring with Lown classification of ventricular arrhythmias, an echocardiogram with left ventricular mass index (LVMI) and a specific type of LVH. QT interval dispersion (QTd) was calculated on 12 leads standard ECG. 75 pts had LVH (LVMI: 172.6 ± 42.95 g/m2) while 35 pts were without LVH (109.3 ± 15.9 g/m2). Non sustained ventricular tachycardia was registered in 13 pts (17.6%) with LVH and 1 female patient without LVH (2.9%). Patients with VT had a considerably higher ILVM (214.9 ± 6.8 vs. 151.9 ± 47.2 g/m2) than the average and higher QTd (73.7 ± 19.1 vs. 55.2 ± 20.2). VT was registered in 3/19 (15.8%) with eccentric nedilated type LVH, 6/38 (15.8%) with concentric LVH, 1/11 (9.1) (disproportional septal LVH) and 3/5 ( 60%) with dilated LVH. Univariate analysis showed a considerable correlation between the degree of arrhythmias and ILVM (p<0.001) and QTd (p=0.012). Ventricular arrhythmias in patients with arterial hypertension are considerably correlated to the degree of LVH expressed in ILVM and QTd.

Abstract 382: Four-tiered Classification of Left Ventricular Hypertrophy Based on Ventricular Concentricity and Dilatation Identifies Ischemic Stroke in the General Population

2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Haoyu Wang ◽  
Kefei Dou ◽  
Jiang He ◽  
Zugui Zhang ◽  
Yingxian Sun
Keyword(s):  
Ischemic Stroke ◽  
Left Ventricular Hypertrophy ◽  
Chinese Population ◽  
Large Scale ◽  
Ventricular Hypertrophy ◽  
Multivariable Analysis ◽  
Left Ventricular ◽  
End Diastolic Volume ◽  
General Chinese Population

Background: Left ventricular hypertrophy (LVH) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of ischemic stroke in a new 4-group LVH classification based on LV concentricity (mass/end-diastolic volume 0.67 ) and indexed LV end-diastolic volume (EDV) in the general Chinese population. Methods: The cross-sectional study consisted of 11,037 general Chinese population (mean age 54 years; 54% women) from Northeast China Rural Cardiovascular Health (NCRCH) study who underwent echocardiography measurement. A 4-tiered classification of LVH was proposed where eccentric LVH is subdivided into “indeterminate hypertrophy (n=484)” and “dilated hypertrophy (n=386)” and concentric LVH into “thick hypertrophy (n=246)” and “both thick and dilated hypertrophy (n=138)” based on the presence of increased LV end-diastolic volume. Results: Compared with normal LV geometry (2.6%), indeterminate (7.4%) and thick hypertrophy (10.2%) showed a higher prevalence of ischemic stroke (p<0.05). Ischemic stroke was significantly greater in participants with indeterminate (adjusted odd ratio [OR]:1.635, 95% confidence interval [CI]: 1.115–2.398) and thick (2.143 [1.329–3.456]) hypertrophy but not significantly in those with dilated (1.251 [0.803–1.950]) and both thick and dilated hypertrophy (0.926 [0.435–1.971]) compared with normal geometry in multivariable analysis. Additionally, the continuous parameters of LV concentricity 0.67 (OR, 1.067; 95% CI, 1.024–1.113 per 1 SD increment) was independently associated with the presence of ischemic stroke in multivariable analysis adjusted for age, sex, race, physical activity, current smoking and drinking status, BMI, TC, hypertension and diabetes, while LVEDV/BSA was not (OR, 0.957; 95% CI, 0.859–1.065 per 1 SD increment). Conclusions: In a large-scale Asian population, we identified that thick hypertrophy carried the greatest odd for ischemic stroke, independently of traditional risk factors, followed by indeterminate hypertrophy. The new 4-tiered categorization of LVH can permit a better understanding of which subjects are at high enough risk for ischemic stroke to warrant early targeted therapy.

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