New advances in fetal cardiovascular magnetic resonance imaging for quantifying the distribution of blood flow and oxygen transport: Potential applications in fetal cardiovascular disease diagnosis and therapy

2017 ◽  
Vol 34 (12) ◽  
pp. 1799-1803 ◽  
Author(s):  
Liqun Sun ◽  
Christopher K. Macgowan ◽  
Sharon Portnoy ◽  
John G. Sled ◽  
Shi-Joon Yoo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cardiovascular Disease ◽  
Blood Flow ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiovascular Magnetic Resonance Imaging ◽  
Disease Diagnosis ◽  
Resonance Imaging ◽  
Potential Applications ◽  
Transport Potential

scholarly journals Phase-contrast magnetic resonance imaging and computational fluid dynamics assessment of thoracic aorta blood flow: a literature review

2019 ◽  
Author(s):  
Omar A Jarral ◽  
Matthew K H Tan ◽  
Mohammad Yousuf Salmasi ◽  
Selene Pirola ◽  
John R Pepper ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiovascular Magnetic Resonance Imaging ◽  
Phase Contrast ◽  
Aortic Disease ◽  
Flow Patterns ◽  
Health Concern ◽  
Resonance Imaging

Abstract The death rate from thoracic aortic disease is on the rise and represents a growing global health concern as patients are often asymptomatic before acute events, which have devastating effects on health-related quality of life. Biomechanical factors have been found to play a major role in the development of both acquired and congenital aortic diseases. However, much is still unknown and translational benefits of this knowledge are yet to be seen. Phase-contrast cardiovascular magnetic resonance imaging of thoracic aortic blood flow has emerged as an exceptionally powerful non-invasive tool enabling visualization of complex flow patterns, and calculation of variables such as wall shear stress. This has led to multiple new findings in the areas of phenotype-dependent bicuspid valve flow patterns, thoracic aortic aneurysm formation and aortic prosthesis performance assessment. Phase-contrast cardiovascular magnetic resonance imaging has also been used in conjunction with computational fluid modelling techniques to produce even more sophisticated analyses, by allowing the calculation of haemodynamic variables with exceptional temporal and spatial resolution. Translationally, these technologies may potentially play a major role in the emergence of precision medicine and patient-specific treatments in patients with aortic disease. This clinically focused review will provide a systematic overview of key insights from published studies to date.

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