Does Left Atrial Enlargement Contribute to Mitral Leaflet Tethering in Patients with Functional Mitral Regurgitation? Proposed Role of Atriogenic Leaflet Tethering

2014 ◽  
Vol 31 (10) ◽  
pp. 1310-1311 ◽  
Author(s):  
Jeffrey J. Silbiger
Keyword(s):  
Mitral Regurgitation ◽  
Left Atrial ◽  
Functional Mitral Regurgitation ◽  
Mitral Leaflet ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals Prognostic Implications of Left Atrial Enlargement in Degenerative Mitral Regurgitation

2019 ◽  
Vol 74 (7) ◽  
pp. 858-870 ◽  
Author(s):  
Benjamin Essayagh ◽  
Clémence Antoine ◽  
Giovanni Benfari ◽  
David Messika-Zeitoun ◽  
Hector Michelena ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement ◽  
Prognostic Implications

P3764Morphological mechanisms of atrial functional mitral regurgitation in patients with atrial fibrillation

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
K Nagaoka ◽  
Y Mukai ◽  
S Kawai ◽  
S Takase ◽  
K Sakamoto ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Left Ventricular Ejection Fraction ◽  
Mitral Regurgitation ◽  
Left Atrial ◽  
Left Ventricular ◽  
Volume Index ◽  
Left Ventricular Ejection ◽  
Functional Mitral Regurgitation ◽  
Mitral Leaflet ◽  
Ventricular Ejection Fraction

Abstract Background Atrial functional mitral regurgitation (AFMR) occurs in patients with atrial fibrillation. However, morphological mechanisms of AFMR are poorly understood. Purpose The purpose of this study was to examine the morphological characteristics in patients with AFMR. Methods Among consecutive 795 patients undergoing initial radiofrequency catheter ablation (RFCA) at our hospital, twenty-five patients with persistent AF accompanied by AFMR (≥ moderate) before RFCA (AFMR group) were studied. Age-matched 25 patients with persistent AF without MR were defined as a control group. Results Left ventricular ejection fraction (LVEF) was lower and left atrium volume index was larger in the AFMR group (Table). Mitral valve annulus diameter and length of anterior mitral leaflet (AML) were similar between groups, whereas length of posterior mitral leaflet (PML) was significantly shorter in the AFMR group. Smaller tethering angle of AML (γ in the figure) and shorter tethering height were significantly associated with the occurrence of AFMR, which were different from morphology of functional mitral regurgitation in patients with dilated LV. Multiple regression analysis revealed that less tenting height (p<0.05) and LA dilatation toward the posterior (p<0.01) were significantly related to AFMR. Echocardiographic parameters AFMR (n=25) Control (n=25) P value Age, y 69±8 66±10 NS Male, n (%) 9 (36) 20 (80) P=0.001 LVEF,% 60±9 67±6 P=0.004 LAD, mm 44±5 41±7 NS LAVI, ml/m2 56±17 41±13 P<0.001 MV diameter, mm 3.9±0.4 3.8±0.5 NS α angle, ° 34±9 35±7 NS β angle, ° 48±9 50±8 NS γ angle, ° 32±5 37±5 P=0.0005 AML length, mm 3.0±0.5 3.0±0.5 NS PML length, mm 2.1±0.1 2.4±0.1 P=0.03 Tenting height, mm 1.5±0.1 1.8±0.1 P=0.02 D, mm 0.8±0.3 0.5±0.3 P=0.001 LVEF: left ventricular ejection fraction; LAD: left atrial diameter; LAVI: left atrial volume index; AML: anterior mitral leaflet; PML: posterior mitral leaftlet. Conclusions AFMR occurs in patients with unique morphological features, such as less tethering height and LA dilatation toward the posterior.

Role of Left Atrial Enlargement in Elevation of N-terminal Probrain Natriuretic Peptide in Ventricular Hypertrophy

2007 ◽  
Vol 13 (6) ◽  
pp. S40-S41
Author(s):  
Yo Murakami ◽  
Hiroyuki Yoshitomi ◽  
Nobuhiro Kodani ◽  
Takashi Sugamori ◽  
Tomoko Adachi ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

scholarly journals The role of left atrial enlargement and age in the prediction of recurrence in embolic strokes of undetermined source

2021 ◽  
Vol 90 (4) ◽  
Author(s):  
Beatriz Mendez ◽  
Cristina Ramos-Ventura ◽  
Carlos Zapata ◽  
Carmen Arteaga ◽  
Eduardo Soriano-Navarro ◽  
...  
Keyword(s):  
Left Atrial ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement
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