Determinants of Functional Mitral Regurgitation Severity in Patients with Ischemic Cardiomyopathy versus Nonischemic Dilated Cardiomyopathy

2013 ◽  
Vol 31 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Dimitrios M. Konstantinou ◽  
Klio Papadopoulou ◽  
George Giannakoulas ◽  
Vasilis Kamperidis ◽  
Emmanouela G. Dalamanga ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Dilated Cardiomyopathy ◽  
Ischemic Cardiomyopathy ◽  
Functional Mitral Regurgitation ◽  
Mitral Regurgitation Severity ◽  
Nonischemic Dilated Cardiomyopathy

scholarly journals Mechanisms of Recurrent Functional Mitral Regurgitation After Mitral Valve Repair in Nonischemic Dilated Cardiomyopathy

Circulation ◽  
2009 ◽  
Vol 119 (19) ◽  
pp. 2606-2614 ◽  
Author(s):  
Alex Pui-Wai Lee ◽  
Michael Acker ◽  
Spencer H. Kubo ◽  
Steven F. Bolling ◽  
Seung W. Park ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Dilated Cardiomyopathy ◽  
Mitral Valve Repair ◽  
Functional Mitral Regurgitation ◽  
Valve Repair ◽  
Nonischemic Dilated Cardiomyopathy

scholarly journals Novel left ventriculoplasty for nonischemic dilated cardiomyopathy with functional mitral regurgitation

2006 ◽  
Vol 131 (1) ◽  
pp. 233-235 ◽  
Author(s):  
Hiroshi Irie ◽  
Tadashi Isomura ◽  
Fumikazu Nomura ◽  
Taiko Horii ◽  
Joji Hoshino ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Dilated Cardiomyopathy ◽  
Functional Mitral Regurgitation ◽  
Nonischemic Dilated Cardiomyopathy

Abstract 4827: Role of Left Ventricular Dyssynchrony in Functional Mitral Regurgitation in Patients with Dilated Cardiomyopathy: A Comparison Study with Geometric Parameters of Mitral Apparatus Estimated with 3d Echocardiography

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Woonggil Choi ◽  
Soohyun Kim ◽  
Seongill Woo ◽  
Deahyuk Kim ◽  
Keumsoo Park ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Dilated Cardiomyopathy ◽  
Multivariate Regression Analysis ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Geometric Parameters ◽  
Functional Mitral Regurgitation ◽  
Left Ventricular Dyssynchrony ◽  
Lv Dyssynchrony ◽  
Mitral Apparatus

Objective: Functional mitral regurgitation (FMR) occurs commonly in patients with dilated cardiomyopathy (DCM). The aim of this study was to compare the roles of Left Ventricle(LV) dyssynchrony and geometric parameters of mitral apparatus as determinants of FMR in patients with DCM. Methods: Fourteen DCM patients without FMR and 15 DCM patients with FMR (ERO = 0.11 ± 0.029 cm 2 ) were enrolled. Effective regurgitant orifice (ERO) area and tissue Doppler-derived dyssynchrony index (DI: the standard deviation of time to peak myocardial systolic contraction of eight segments) were measured. The estimated DIs were corrected by the cycle length (CL) of each patient (cDI (%) = DI/CL*100). Using real-time 3D echocardiogrphy, mitral tenting area (MVT) and the degrees of displacement of anterior (APMD) and posterior (PPMD) papillary muscles were estimated. All geometric measurements were corrected (c) by the height of each patient. Results: There was no significant (p > 0.05) difference in LV Ejection Fraction and cLVEDV between two patient groups. cDI, cMVT, cAPMD and cPPMD significantly (p < 0.05) increased in the patient with FMR comparing with those in patients without FMR. cDI (r = 0.42), cMVT (r = 0.74), cAPMD (r = 0.63) and cPPMD (r = 0.64) showed significant (p < 0.05) correlations with ERO. cMVT was found to the strongest independent predictor of ERO with multivariate regression analysis, whereas cDI did not enter into the model. Conclusions: The degree of MV tenting rather than LV dyssynchrony was found to be the main determinant of FMR in DCM. However LV dyssynchrony also has a minor independent association with FMR.

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