Investigating the breast cancer screening–treatment–mortality pathway of women diagnosed with invasive breast cancer: Results from linked health data

2021 ◽  
Author(s):  
Ming Li ◽  
Michelle Reintals ◽  
Katina D'Onise ◽  
Gelareh Farshid ◽  
Andrew Holmes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Invasive Breast Cancer ◽  
Health Data ◽  
Treatment Mortality

scholarly journals Changing trends in proportional incidence and net survival of screened and nonscreened breast cancers among women in England

2019 ◽  
Author(s):  
Haiyan Wu ◽  
Kwok Wong ◽  
Shou-En Lu ◽  
John Broggio ◽  
Lanjing Zhang
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Invasive Breast Cancer ◽  
Temporal Trends ◽  
Breast Cancers ◽  
Upward Trend ◽  
Net Survival ◽  
Survival Difference ◽  
Proportional Incidence

AbstractBackgroundUptake of breast cancer screening has been decreasing in England since 2007, and may increase proportional incidence of nonscreened cancers. However, recent trends in proportional incidence and net-survivals of screened and nonscreened breast cancers are unclear.MethodsWe extracted population-based proportional incidence and age-standardized 5-year net-survivals from Public Health England, for English women with invasive breast cancer diagnosed during 1995-2011 (linked to death certificates, followed through 2016). Piecewise log-linear models with change-point/joinpoint were used to estimate temporal trends. We conducted a quasi-experimental study to test the hypothesis that the trend-change year of proportional incidence coincided with that of 5-year net-survival.ResultsAmong 254,063 women in England with invasive breast cancer diagnosed during 1995-2011, there was downward-to-upward trend-change in proportional incidence of nonscreened breast cancers (annual percent change[APC]=5.6 after 2007 versus APC=-3.5 before 2007, P<0.001) in diagnosis-year 2007, when steeper upward-trend in age-standardized 5-year net survival started (APC=5.7 after 2007/2008 versus APC=0.3 before 2007/2008, P<0.001). Net-survival difference of screened versus nonscreened cancers also significantly narrowed (18% in 2007/2008 versus 5% in 2011). Similar associations were found in all strata of race, cancer stage, grade and histology, except in Black patients or patients with stage I, stage III, or grade I cancer.ConclusionsThe downward-to-upward trend-change in proportional incidence of nonscreened breast cancers is associated with steeper upward-trend in age-standardized 5-year net survival among English women in recent years. Survival benefits of breast cancer screening appear decreasing in recent years. The data support reduction of breast cancer screening in some patients.

Abstract #424 Breast Cancer Screening In Transgender Females on Hormone Therapy

2019 ◽  
Vol 25 ◽  
pp. 201-202
Author(s):  
Mary Stevenson ◽  
Robert Sineath ◽  
Michael Goodman ◽  
Vin Tangpricha
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Hormone Therapy ◽  
Breast Cancer Screening
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