scholarly journals A qualitative exploration of the meaning of the term “survivor” to young women living with a history of breast cancer

2018 ◽  
Vol 27 (3) ◽  
pp. e12847 ◽  
Author(s):  
S. Rees
Keyword(s):  
Breast Cancer ◽  
Young Women ◽  
History Of ◽  
Qualitative Exploration ◽  
Term Survivor

scholarly journals Long-term effects of first degree family history of breast cancer in young women: Recurrences and bilateral breast cancer

2015 ◽  
Vol 55 (4) ◽  
pp. 449-454 ◽  
Author(s):  
Jan J. Jobsen ◽  
Job van der Palen ◽  
Mariël Brinkhuis ◽  
Francisca Ong ◽  
Henk Struikmans
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Young Women ◽  
Bilateral Breast Cancer ◽  
Long Term Effects ◽  
History Of

Genetic testing in young women with breast cancer: Results from a web-based survey

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 21093-21093
Author(s):  
J. A. Shin ◽  
S. Gelber ◽  
J. Garber ◽  
R. Rosenberg ◽  
M. Przypyszny ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ovarian Cancer ◽  
Genetic Testing ◽  
Family History ◽  
High Risk ◽  
Young Women ◽  
College Education ◽  
Web Based ◽  
Increased Risk ◽  
History Of

21093 Background: Young women with breast cancer have an increased risk of harboring a BRCA1/2 mutation. The frequency of genetic testing in this population is not well described. We evaluated the reported frequency and factors associated with genetic testing among young breast cancer survivors identified through the Young Survival Coalition (YSC), an international advocacy group for young women with breast cancer. Methods: Items regarding family history and genetic testing were included in a large web-based survey addressing quality of life and fertility issues for young women with breast cancer. All YSC members were invited by email in March 2003 (N= 1,703 women) to participate in this cross-sectional survey. Results: 657 women completed the on-line survey; 622 were eligible for this analysis (age <40, no metastatic or recurrent disease). Mean age at breast cancer diagnosis was 33 years; mean age when surveyed 35.5 years. Stages included: 0 (10%), I (27%), II (49%), III (12%), missing (3%). 90% of women were white; 64% married; 49% with children; 78% had at least a college education; 42% of women reported a 1st or 2nd degree relative with breast or ovarian cancer, and 13% considered themselves high-risk for harboring a genetic mutation at the time of diagnosis. At the time of the survey, 23% of women had undergone genetic testing, and 26% of those tested reported that a mutation was found. In a multivariate model, women who were younger (age 36–40 vs. age =30, O.R. 2.26, p=0.004), more educated (< college vs. > college education, O.R. 2.62, p=0.0009), had a family history of breast or ovarian cancer (O.R. 3.15, p<0.0001), and had had a mastectomy (O.R. 1.99, p=0.001) were more likely to have undergone genetic testing. Non-significant covariates included: age at survey, stage, time since diagnosis, race, marital status, employment, finances, insurance, number of children, comorbidities, baseline anxiety and depression, and fear of recurrence. Conclusion: The majority of women diagnosed with breast cancer age 40 and younger do not undergo genetic testing. Younger, more educated women with a family history of breast or ovarian cancer are more likely to get tested. Further research to define the appropriateness of genetic testing in this relatively high-risk population is warranted. No significant financial relationships to disclose.

624 Physical examination is a valuable tool in the follow up of young women with a history of early breast cancer

2010 ◽  
Vol 8 (3) ◽  
pp. 240 ◽  
Author(s):  
G. de Bock ◽  
W.L. Lu ◽  
M. Schaapveld ◽  
P.C. Baas ◽  
L.M. Hansen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Examination ◽  
Early Breast Cancer ◽  
Young Women ◽  
History Of

scholarly journals Young women with family history of breast cancer and their risk factors for benign breast disease

Cancer ◽  
2011 ◽  
Vol 118 (11) ◽  
pp. 2796-2803 ◽  
Author(s):  
Catherine S. Berkey ◽  
Rulla M. Tamimi ◽  
Bernard Rosner ◽  
A. Lindsay Frazier ◽  
Graham A. Colditz
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Family History ◽  
Young Women ◽  
Benign Breast Disease ◽  
Breast Disease ◽  
History Of

scholarly journals Risk of Asynchronous Contralateral Breast Cancer in Noncarriers of BRCA1 and BRCA2 Mutations With a Family History of Breast Cancer: A Report From the Women's Environmental Cancer and Radiation Epidemiology Study

2013 ◽  
Vol 31 (4) ◽  
pp. 433-439 ◽  
Author(s):  
Anne S. Reiner ◽  
Esther M. John ◽  
Jennifer D. Brooks ◽  
Charles F. Lynch ◽  
Leslie Bernstein ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Young Women ◽  
Contralateral Breast Cancer ◽  
Contralateral Breast ◽  
Brca1 And Brca2 ◽  
Bilateral Disease ◽  
History Of ◽  
Brca2 Mutations ◽  
Brca1 And Brca2 Mutations

Purpose To fully characterize the risk of contralateral breast cancer (CBC) in patients with breast cancer with a family history who test negative for BRCA1 and BRCA2 mutations. Patients and Methods From our population-based case-control study comparing women with CBC to women with unilateral breast cancer (UBC), we selected women who tested negative for BRCA1 and BRCA2 mutations (594 patients with CBC/1,119 control patients with UBC). Rate ratios (RRs) and 95% CIs were estimated to examine the association between family history of breast cancer and risk of asynchronous CBC. Age- and family history–specific 10-year cumulative absolute risks of CBC were estimated. Results Family history of breast cancer was associated with increased CBC risk; risk was highest among young women (< 45 years) with first-degree relatives affected at young ages (< 45 years; RR, 2.5; 95% CI, 1.1 to 5.3) or women with first-degree relatives with bilateral disease (RR, 3.6; 95% CI, 2.0 to 6.4). Women diagnosed with UBC before age 55 years with a first-degree family history of CBC had a 10-year risk of CBC of 15.6%. Conclusion Young women with breast cancer who have a family history of breast cancer and who test negative for deleterious mutations in BRCA1 and BRCA2 are at significantly greater risk of CBC than other breast cancer survivors. This risk varies with diagnosis age, family history of CBC, and degree of relationship to an affected relative. Women with a first-degree family history of bilateral disease have risks of CBC similar to mutation carriers. This has important implications for the clinical management of patients with breast cancer with family history of the disease.

scholarly journals Body Image in BRCA-Positive Young Women Following Bilateral Risk-Reducing Mastectomy: A Review of the Literature

2021 ◽  
Vol 12 ◽  
Author(s):  
Christa Torrisi
Keyword(s):  
Breast Cancer ◽  
Body Image ◽  
Young Women ◽  
Intimate Relationships ◽  
Life Stage ◽  
Review Of The Literature ◽  
Quantitative Studies ◽  
History Of ◽  
Risk Reducing ◽  
Brca Gene Mutation

Background/Significance: The presence of a breast cancer (BRCA) gene mutation increases a woman’s lifetime risk of developing breast cancer. Bilateral risk-reducing mastectomy is a proactive treatment option which lowers that risk. However, breast removal can create a change in physical appearance. It is unclear if BRCA-positive women undergoing this surgery in young adulthood, a life stage where intimate relationships, families, and careers are being established, have the same experience with body image as women in later stages of life.Purpose: The aim of this literature review is to assess how bilateral risk-reducing mastectomy impacts body image in young BRCA-positive women less than 40 years of age, with no history of breast cancer.Methods: Database searches were performed, yielding 402 results. Studies were considered if participants had an increased lifetime breast cancer risk/BRCA-positive diagnosis and history of bilateral risk-reducing mastectomy, body image was evaluated, and mean age was less than 40 years. A total of three qualitative studies and three quantitative studies were identified as relevant for this review.Results: A dearth of information exists on body image in young women following bilateral risk-reducing mastectomy. It was found in this review that some women experienced a decline in body image following surgery, while in others body image was maintained or improved.Conclusion: Understanding factors that impact body image following this risk-reducing surgery will allow clinicians to support this unique population. Open and informative discussion should be encouraged with young women considering, or who have undergone, bilateral risk-reducing mastectomy.

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