IL‐17A inhibitors in patients with chronic plaque psoriasis and history of malignancy: A case series with systematic literature review

2021 ◽  
Author(s):  
Francesco Bellinato ◽  
Paolo Gisondi ◽  
Martina Maurelli ◽  
Giampiero Girolomoni
2013 ◽  
Vol 16 (7) ◽  
pp. A504
Author(s):  
S.R. Feldman ◽  
C. Burudpakdee ◽  
S. Gala ◽  
U. Mallya

2020 ◽  
Vol 15 ◽  
Author(s):  
Ajeet Singh ◽  
Ritul Choudhary ◽  
Namrata Chhabra ◽  
Satyaki Ganguly ◽  
Vinay Rathore

: Methotrexate is an antimetabolite anticancer drug frequently used in the treatment of extensive chronic plaque psoriasis. Psoriatic plaque erosion is a rare toxic side effect of single-dose methotrexate and is described as a sign of the impending pancytopenia. Here, we report a case of a 48-year-old male, presented with multiple oral and genital erosions, fissuring over palm and soles for 5 days. His laboratory tests revealed severe pancytopenia and nephropathy. He had a history of chronic plaque psoriasis for which he took a single dose of 15 mg methotrexate. During the hospital stay, the patient needed folate antagonist, granulocyte colony stimulating factor (G-CSF), intravenous fluids, blood transfusions, and platelet transfusions. He recovered within 12 days of admission.


2021 ◽  
Author(s):  
Christine Prodinger ◽  
Subhanitthaya Chottianchaiwat ◽  
Jemima E. Mellerio ◽  
John A. McGrath ◽  
Linda Ozoemena ◽  
...  

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