A novel association of efavirenz induced severe cutaneous adverse reactions with HLA ‐ DRB1 *03:01: A case‐control study from North‐East India

2021 ◽  
Author(s):  
Mehak Singh ◽  
Manoj Pawar ◽  
Shashank Bhargava ◽  
Prakhar Gupta ◽  
Pankaj Adhicari
Keyword(s):  
Adverse Reactions ◽  
Case Control Study ◽  
Case Control ◽  
North East India ◽  
North East ◽  
Novel Association ◽  
Severe Cutaneous Adverse Reactions ◽  
Cutaneous Adverse Reactions ◽  
Control Study

An international collaborative case-control study of severe cutaneous adverse reactions (SCAR). Design and methods

1995 ◽  
Vol 48 (9) ◽  
pp. 1099-1108 ◽  
Author(s):  
Judith Parsells Kelly ◽  
Ariane Auquier ◽  
Berthold Rzany ◽  
Luigi Naldi ◽  
Sylvie Bastuji-Garin ◽  
...  
Keyword(s):  
Adverse Reactions ◽  
Case Control Study ◽  
Case Control ◽  
Severe Cutaneous Adverse Reactions ◽  
International Collaborative ◽  
Design And Methods ◽  
Cutaneous Adverse Reactions ◽  
Control Study

Gene-diet interactions in the aetiology of colorectal cancer: results from a population-based case-control study in north-east Scotland

Endoscopy ◽  
2006 ◽  
Vol 37 (12) ◽  
Author(s):  
L Sharp ◽  
LF Masson ◽  
J Little ◽  
NT Brockton ◽  
SC Cotton ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
North East ◽  
Control Study

scholarly journals A case-control study of cervical cancer screening in north east Scotland.

BMJ ◽  
1985 ◽  
Vol 290 (6481) ◽  
pp. 1543-1546 ◽  
Author(s):  
J E Macgregor ◽  
S M Moss ◽  
D M Parkin ◽  
N E Day
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Case Control Study ◽  
Case Control ◽  
North East ◽  
Control Study

scholarly journals Socioeconomic, environmental, and behavioural risk factors for leprosy in North-east Brazil: results of a case–control study

2006 ◽  
Vol 35 (4) ◽  
pp. 994-1000 ◽  
Author(s):  
Ligia RS Kerr-Pontes ◽  
Maurício L Barreto ◽  
Clara MN Evangelista ◽  
Laura C Rodrigues ◽  
Jorg Heukelbach ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Behavioural Risk Factors ◽  
North East ◽  
Control Study

scholarly journals Association Of Food And Drug Allergy With Antituberculosis Drug Related Hepatitis Or Skin Reactions: A Case Control Study

2014 ◽  
Vol 10 (2) ◽  
pp. 48-53
Author(s):  
Dinesh LB Dassanayake ◽  
BKM Asanga Upul ◽  
K Wickramasekara ◽  
SK Ileperuma ◽  
A Siribaddana ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Adverse Reactions ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Drug Induced ◽  
Skin Reactions ◽  
Dence Interval ◽  
History Of ◽  
Control Study

Introduction: Anti-tuberculosis drugs can cause adverse reactions including hepatitis and skin reactions. This case control study was aimed at fi nding out whether allergy to drug or food acts as a risk factor for the development of anti-tuberculosis drug induced hepatitis or skin reactions. Patients with tuberculosis on category 1 regimen, who presented to the Teaching Hospital Kandy Sri Lanka, due to anti-tuberculosis drug induced hepatitis or skin reactions from 1st July 2010 to 30th June 2011 were recruited. Methodology: Patients with drug induced hepatitis or skin reactions were grouped as cases and patients who didn’t develop hepatitis or skin reactions during the treatment period were selected as controls. Controls were matched for age, gender, weight, and consumption of alcohol. Cases and controls were inquired for the presence of allergy to drugs or food. Two groups were compared using odds ratio. Results: There were 61 cases [33 (54.1%) males, 28 (45.9%) females] and 61 controls .Ten patients (16.39%) among the cases had allergy to food or drugs while in control group only 2 (03.2%) had allergy. Odds ratio for the development of drug reactions in patients with a history of allergy was 5.8 (confi dence interval 1.2 to 27.6). Conclusion: Patients with allergy to drugs or foods have 5.8 times risk of developing anti-tuberculosis drug induced hepatitis or skin reaction. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2013; X(2); 48-53 DOI: http://dx.doi.org/10.3126/saarctb.v10i2.9714

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