scholarly journals Retention and survival rate of etanercept in psoriasis over 15 years and patient outcomes during the COVID ‐19 pandemic: The real‐world experience of a single center

2020 ◽  
Author(s):  
Nahide Onsun ◽  
Begüm Güneş ◽  
Ayşegül Yabacı
BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tae-Hwan Kim ◽  
Hun Do Cho ◽  
Yong Won Choi ◽  
Hyun Woo Lee ◽  
Seok Yun Kang ◽  
...  

Abstract Background Since the results of the ToGA trial were published, trastuzumab-based chemotherapy has been used as the standard first-line treatment for HER2-positive recurrent or primary metastatic gastric cancer (RPMGC). However, the real-world data has been rarely reported. Therefore, we investigated the outcomes of trastuzumab-based chemotherapy in a single center. Methods This study analyzed the real-world data of 47 patients with HER2-positive RPMGC treated with trastuzumab-based chemotherapy in a single institution. Results With the median follow-up duration of 18.8 months in survivors, the median overall survival (OS) and progression-free survival were 12.8 and 6.9 months, respectively, and the overall response rate was 64%. Eastern Cooperative Oncology Group performance status 2 and massive amount of ascites were independent poor prognostic factors for OS, while surgical resection before or after chemotherapy was associated with favorable OS, in multivariate analysis. In addition, 5 patients who underwent conversion surgery after chemotherapy demonstrated an encouraging median OS of 30.8 months, all with R0 resection. Conclusions Trastuzumab-based chemotherapy in patients with HER2-positive RPMGC in the real world demonstrated outcomes almost comparable to those of the ToGA trial. Moreover, conversion surgery can be actively considered in fit patients with a favorable response after trastuzumab-based chemotherapy.


2019 ◽  
Vol 19 ◽  
pp. S238
Author(s):  
Razan Mohty ◽  
Radwan Massoud ◽  
Zaher Chakhachiro ◽  
Rami Mahfouz ◽  
Samer Nassif ◽  
...  

2019 ◽  
Vol 42 (6) ◽  
pp. 763-763
Author(s):  
Juan J. García Guerrero ◽  
Joaquín Fernández de la Concha Castañeda ◽  
Manuel Doblado Calatrava ◽  
Ángel Redondo Méndez ◽  
Manuel Lázaro Medrano ◽  
...  

2019 ◽  
Vol 42 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Juan J. García Guerrero ◽  
Joaquín Fernández de la Concha Castañeda ◽  
Manuel Doblado Calatrava ◽  
Ángel Redondo Méndez ◽  
Manuel Lázaro Medrano ◽  
...  

2015 ◽  
Vol 18 (2) ◽  
pp. 181 ◽  
Author(s):  
Sombat Muengtaweepongsa ◽  
Pornpoj Prapa-Anantachai ◽  
PornpatrA Dharmasaroja ◽  
Pattarawit Rukkul ◽  
Pornchai Yodvisitsak

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S794
Author(s):  
F. Ratti ◽  
F. Cipriani ◽  
G. Fiorentini ◽  
V. Burgio ◽  
M. Ronzoni ◽  
...  

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