Efficacy and safety of risankizumab in psoriasis patients who failed anti‐IL ‐17, anti‐12/23 and/or anti IL ‐23: Preliminary data of a real‐life 16‐week retrospective study

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Matteo Megna ◽  
Gabriella Fabbrocini ◽  
Angelo Ruggiero ◽  
Eleonora Cinelli
2016 ◽  
Vol 27 (6) ◽  
pp. 525-530 ◽  
Author(s):  
Francesco Ricci ◽  
Sara Tambone ◽  
Luca Neri ◽  
Luca Fania ◽  
Antonella Piccioni ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Clémentine Carlet ◽  
Damien Bichard ◽  
Marie Aleth Richard ◽  
Emmanuel Mahé ◽  
Clémence Saillard ◽  
...  

Background. Although infliximab (IFX) has been available since 2005, there are very little data on the long-term drug survival of infliximab in real-life. Objective. Our aim was to identify and describe psoriasis patients treated with IFX for longer than 6 years. Methods. Psoriasis patients treated with IFX for longer than 6 years were retrospectively included. Demographic and clinical data were collected in May 2018. Results. Between January 2005 and December 2012, 43 patients were maintained on IFX for 6 years or longer. IFX was introduced as a 4.5 line of systemic therapy. The mean duration of IFX treatment was 8.5 years (6–12). In May 2018, 30 patients (70%) were still maintained on IFX at 4–6 mg/kg every 8–10 weeks with an efficiency of about 100%. IFX was stopped in 13 patients (30%) mainly for loss of efficacy in 6 patients (46%). Three patients developed solid cancer including bladder cancer, lung cancer, and prostate cancer. Limitation. Retrospective study. Conclusion. We report the efficacy and safety of IFX maintained for up to 12 years in psoriasis patients. The long-term use of IFX was associated with a high BMI confirming the critical role of weight-based dosing for this drug.


Author(s):  
Claudio Urbani ◽  
Francesca Dassie ◽  
Benedetta Zampetti ◽  
Di Certo Agostino Maria ◽  
Renato Cozzi ◽  
...  

2019 ◽  
Vol 35 (3) ◽  
pp. 172-177
Author(s):  
Ploysyne Rattanakaemakorn ◽  
Phanitchanat Phusuphitchayanan ◽  
Kallapan Pakornphadungsit ◽  
Kunlawat Thadanipon ◽  
Poonkiat Suchonwanit

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