Therapeutic implications of C‐reactive protein and uric acid in patients with psoriasis before and after narrow band ultraviolet B therapy

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Mamoun Shalaby ◽  
Ahmad Elshahid ◽  
Ahmed Metwaly ◽  
Ayda Ibrahim ◽  
Mohammad Jafferany ◽  
...  
Keyword(s):  
Uric Acid ◽  
Narrow Band ◽  
Ultraviolet B ◽  
C Reactive Protein ◽  
Therapeutic Implications ◽  
Reactive Protein ◽  
Before And After

Evaluation of High-Sensitive C Reactive Protein Serum Level in Patients with Chronic Plaque Psoriasis before and After Treatment with Narrow Band Ultraviolet B Therapy or Methotrexate Comparative Study

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Lobna Ebrahim Eldahshan ◽  
Saleh Mohammed ElShiemy ◽  
Rania Mahmoud El Husseiny ◽  
Wael Mohammed Saudy
Keyword(s):  
Serum Level ◽  
Plaque Psoriasis ◽  
Narrow Band ◽  
Ultraviolet B ◽  
C Reactive Protein ◽  
Chronic Plaque Psoriasis ◽  
Reactive Protein ◽  
Before And After ◽  
Protein Serum ◽  
Psoriasis Severity

Abstract Background Psoriasis is a chronic, recurring inflammatory disease affecting the skin, joints and nails that has a significant negative impact on the quality of life.Highly sensitive c reactive protein ( hsCRP) could be useful as biomarker for assessing the psoriasis severity(1). Objectives Assess the changes in high-sensitive C-reactive protein serum level in patients with chronic plaque psoriasis before and after treatment with narrow band ultraviolet B therapy and Methotrexate. Patients and Methods Our Prospective clinical study included 40 patients of both sex, aged 20-60 years old with psoriasis vulgaris recruited from dermatology outpatient clinic of Ain Shams University Hospital from January 2018 to December 2018. The study was approved by Ain Shams University ethical committee. Informed consents were taken from each Patient after full description of the study aims and procedures Results Both methotrexate and nb-uvb showed significant decrease in serum level hscrp ,PASI score and DLQI after 12 weeks of treatment ,although there were statistically significant lower PASI , DLQI scores and serum level hscrp after 12 weeks of treatment in methotrexate group of patient compared to nb-uvb group of patients Conclusion Highly sensitive C reactive protein(hscrp) is a promising inflammatory marker for monitoring psoriasis severity and efficacy of treatment respectively .Methotrexate treatment showed significant effect on psoriasis severity regarding lowering hscrp serum level ,PASI and DLQI in compared to Nb_UVB therapy .

scholarly journals C-reactive protein serum level in patients with psoriasis before and after treatment with narrow-band ultraviolet B

2016 ◽  
Vol 91 (5) ◽  
pp. 580-583 ◽  
Author(s):  
Mahmoud Farshchian ◽  
Akram Ansar ◽  
Mohammadreza Sobhan ◽  
Valiollah Hoseinpoor
Keyword(s):  
Serum Level ◽  
Narrow Band ◽  
Ultraviolet B ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Before And After ◽  
Protein Serum

Chronic Induction of C-Reactive Protein by Hemodialysis, but Not by Peritoneal Dialysis Therapy

1996 ◽  
Vol 16 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Marion Haubitz ◽  
Reinhard Brunkhorst ◽  
Eike Wrenger ◽  
Peter Froese ◽  
Matthias Schulze ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Insufficiency ◽  
Chronic Renal Insufficiency ◽  
Inflammatory Activity ◽  
C Reactive Protein ◽  
Dialysis Therapy ◽  
Dialysis Treatment ◽  
Reactive Protein ◽  
Before And After ◽  
Patient Groups

Objective Evaluation of the inflammatory activity in patients on chronic peritoneal dialysis (PD) and patients on chronic hemodialysis (HD) in comparison to patients with chronic renal insufficiency without dialysis treatment and healthy volunteers. Design Open, non randomized prospective study. Setting Nephrology Department, including HD and PD therapy in a university hospital. Patients Twenty -four patients on chronic PD, 21 patients on chronic HD therapy using a cuprophan dialyzer, 16 patients with chronic renal insufficiency without dialysis treatment, and 33 healthy volunteers; 8 additional patients before and after initiation of chronic HD therapy. All patients and controls were without infection or immunosuppressive therapy. Main Outcome Measures As a marker of the inflammatory activity in the different patient groups, C-reactive protein (CAP) was measured serially using a sensitive, enzyme-Iinked, immunosorbent assay in order to detect values below the detection limit of standard assays. Results All patient groups had CAP levels higher than the normal controls (p < 0.01). Patients on HD had CAP levels significantly higher than PD patients (p < 0.01) whose levels were comparable to patients without dialysis therapy. Accordingly, longitudinal measurements before and after initiation of chronic HD showed a significant increase in CAP levels after the beginning of HD treatment (p < 0.04). Conclusions The results suggest that induction of the inflammatory activity is lower during PD compared to HD, since stimulation by the dialyzer membrane, dialysate buffer, or bacterial fragments in the dialysate is avoided. This observation might indicate a possible lower risk of long-term complications in patients with PD.

Comparison of the Neutrophil/Lymphocyte Ratio and C-Reactive Protein Levels in Patients With Amputation for Diabetic Foot Ulcers

2017 ◽  
Vol 16 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Hasan Metineren ◽  
Turan Cihan Dülgeroğlu
Keyword(s):  
Diabetic Foot ◽  
Inflammatory Marker ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
C Reactive Protein ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Protein Levels ◽  
Reactive Protein ◽  
Before And After

This study compared the effectiveness of the neutrophil/lymphocyte ratio (NLR) versus C-reactive protein (CRP) for evaluating the prognosis and degree of inflammation in patients with amputation for a diabetic foot ulcer (DFU). This study enrolled 56 patients with amputations for DFU with gangrene and compared the CRP levels and NLR measured before and after surgery. Overall, 24 patients (42%) died within 2 weeks postoperatively. Mortality increased with a preoperative/postoperative CRP difference ≤1.5 ( P < .001) and age 73 years or older ( P < .001). The postoperative NLR was lower than the preoperative value but was not significant as a prognostic or inflammatory marker ( P = .945). An increasing serum CRP level is a significant predictor of mortality. CRP and old age are reliable prognostic factors in patients with DFU.

Association between serum uric acid, high sensitive C-reactive protein and pro-oxidant-antioxidant balance in patients with metabolic syndrome

BioFactors ◽  
2018 ◽  
Vol 44 (3) ◽  
pp. 263-271 ◽  
Author(s):  
Mahsa Ahmadnezhad ◽  
Seyed Rafie Arefhosseini ◽  
Mohammad Reza Parizadeh ◽  
Shima Tavallaie ◽  
Maryam Tayefi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals Correlation Between C-reactive Protein and Non-enzymatic Antioxidants (Albumin, Ferritin, Uric Acid and Bilirubin) in Hemodialysis Patients

2015 ◽  
Vol 27 (2) ◽  
pp. 87 ◽  
Author(s):  
Amela Beciragic ◽  
Halima Resic ◽  
Nejra Prohic ◽  
Jasenko Karamehic ◽  
Ajdin Smajlovic ◽  
...  
Keyword(s):  
Uric Acid ◽  
Hemodialysis Patients ◽  
Enzymatic Antioxidants ◽  
C Reactive Protein ◽  
Reactive Protein
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