Muscle Atrophy Beyond the Clinical Effect After a Single Dose of OnabotulinumtoxinA Injected in the Procerus Muscle: A Study with Magnetic Resonance Imaging

2013 ◽  
Vol 39 (5) ◽  
pp. 761-765 ◽  
Author(s):  
Inga K. Koerte ◽  
Sebastian A. Schroeder ◽  
Urban M. Fietzek ◽  
Ingo Borggraefe ◽  
Martina Kerscher ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Single Dose ◽  
Magnetic Resonance ◽  
Muscle Atrophy ◽  
Clinical Effect ◽  
Resonance Imaging

Magnetic resonance imaging of denervation-induced muscle atrophy: Effects of clenbuterol in the rat

2001 ◽  
Vol 24 (12) ◽  
pp. 1647-1658 ◽  
Author(s):  
Michael D. Cockman ◽  
Melissa B. Jones ◽  
Marla C. Prenger ◽  
Russell J. Sheldon
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Muscle Atrophy ◽  
Resonance Imaging

Clinical effect of add-on Primovist-enhanced magnetic resonance imaging on preoperative tumor staging in hepatocellular carcinoma patients

2016 ◽  
Vol 114 (1) ◽  
pp. 106-111
Author(s):  
Young-Joo Jin ◽  
Jin-Woo Lee ◽  
Oh Sang Kwon ◽  
Young Kul Jung ◽  
Jung Hyun Kwon ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hepatocellular Carcinoma ◽  
Magnetic Resonance ◽  
Clinical Effect ◽  
Tumor Staging ◽  
Resonance Imaging

scholarly journals Cerebral Functional Magnetic Resonance Imaging Activation Modulated by a Single Dose of the Monoamine Neurotransmission Enhancers Fluoxetine and Fenozolone during Hand Sensorimotor Tasks

1999 ◽  
Vol 19 (12) ◽  
pp. 1365-1375 ◽  
Author(s):  
Isabelle Loubinoux ◽  
Keder Boulanouar ◽  
Jean-Philippe Ranjeva ◽  
Christophe Carel ◽  
Isabelle Berry ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Single Dose ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Motor Activity ◽  
Healthy Subjects ◽  
Drug Effects ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

Fluoxetine inhibits the reuptake of serotonin, and dextroamphetamine enhances presynaptic release of monoamines. Although the excitatory effect of both noradrenaline and dopamine on motor behavior generally is accepted, the role of serotonin on motor output is under debate. In the current investigation, the authors evidenced a putative role of monoamines and, more specifically, of serotonin in the regulation of cerebral motor activity in healthy subjects. The effects on cerebral motor activity of a single dose of fluoxetine (20 mg), an inhibitor of serotonin reuptake, and fenozolone (20 mg/50 kg), an amphetamine-like drug, were assessed by functional magnetic resonance imaging. Subjects performed sensorimotor tasks with the right hand. Functional magnetic resonance imaging studies were performed in two sessions on two different days. The first session, with two scan experiments separated by 5 hours without any drug administration, served as time-effect control. A second, similar session but with drug administration after the first scan assessed drug effects. A large increase in evoked signal intensity occurred in the ipsilateral cerebellum, and a parallel, large reduction occurred in primary and secondary motor cortices (P < 10–3). These results are consistent with the known effects of habituation. Both drugs elicited comparable effects, that is, a more focused activation in the contralateral sensorimotor area, a greater involvement of posterior supplementary motor area, and a widespread decrease of bilateral cerebellar activation (P < 10–3). The authors demonstrated for the first time that cerebral motor activity can be modulated by a single dose of fluoxetine or fenozolone in healthy subjects. Drug effects demonstrated a direct or indirect involvement of monoamines and serotonin in the facilitation of cerebral motor activity.

Schwannomas of the Upper Extremity

2000 ◽  
Vol 25 (6) ◽  
pp. 604-607 ◽  
Author(s):  
H. J. KANG ◽  
S. J. SHIN ◽  
E. S. KANG
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Muscle Atrophy ◽  
Clinical Characteristics ◽  
Neurological Complications ◽  
Resonance Imaging ◽  
Postoperative Results ◽  
Mri Features ◽  
Microsurgical Techniques ◽  
Hypothenar Muscle

This study presented the clinical characteristics, MRI features and postoperative results of 20 schwannomas in the arms of 13 patients. Twelve tumours had a positive Tinel’s sign, one caused weakness of the wrist and another in Guyon’s canal caused hypothenar muscle atrophy. Of the nine cases which underwent magnetic resonance imaging preoperatively, six were correctly diagnosed as schwannomas. All masses were excised using microsurgical techniques and two transient neurological complications occurred.

Volumetric analysis of vocal fold atrophy via magnetic resonance imaging

2018 ◽  
Vol 132 (9) ◽  
pp. 822-826 ◽  
Author(s):  
S Saint-Victor ◽  
E Barbarite ◽  
C Sidani ◽  
R Bhatia ◽  
D E Rosow
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Muscle Atrophy ◽  
Intraclass Correlation ◽  
Age Groups ◽  
Retrospective Chart Review ◽  
Resonance Imaging ◽  
Age Related ◽  
Significant Difference ◽  
Thyroarytenoid Muscle

AbstractObjectiveTo quantitatively test the hypothesis that older patients have increased thyroarytenoid muscle atrophy by comparing thyroarytenoid muscle volumes across different age groups.MethodsA retrospective chart review was conducted. The study included 111 patients with no history of laryngeal pathology. Two investigators reviewed magnetic resonance imaging studies of these patients and manually traced the thyroarytenoid muscles on multiple slices bilaterally. Thyroarytenoid muscle volumes were then computed using imaging analysis software. Patients were stratified into three age groups (18–50 years, 51–64 years, and 65 years or older) for comparison.ResultsIntra- and inter-rater reliabilities were excellent for all measurements (intraclass correlation co-efficient > 0.90). There was no statistically significant difference in the mean volumes of left and right thyroarytenoid muscles in all age and gender groups.ConclusionGiven the lack of statistically significant difference in thyroarytenoid muscle volume between age groups on magnetic resonance imaging, the prevailing assumption that age-related thyroarytenoid muscle atrophy contributes to presbyphonia should be re-examined.

scholarly journals The influence of fatty infiltration and muscle atrophy of the rotator cuff muscles on midterm functional outcomes in total shoulder resurfacing at six years’ follow-up

2018 ◽  
Vol 12 (2) ◽  
pp. 91-98
Author(s):  
Gray AD Edwards ◽  
Philip A McCann ◽  
Michael R Whitehouse ◽  
Charles J Wakeley ◽  
Partha P Sarangi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Rotator Cuff ◽  
Muscle Atrophy ◽  
Functional Outcomes ◽  
Fatty Infiltration ◽  
Resonance Imaging ◽  
Shoulder Replacement ◽  
Total Shoulder Replacement

Background We report functional outcomes at six years in patients with varying degrees of fatty infiltration and atrophy of the rotator cuff muscles who have undergone anatomic total shoulder replacement. Methods A retrospective analysis of case notes and magnetic resonance imaging scans of patients undergoing total shoulder replacement for primary glenohumeral arthritis was performed. Patients were grouped based upon their pre-operative magnetic resonance imaging findings for fatty infiltration, muscle area and tendinopathy. Post-operative functional outcomes were assessed using the Oxford Shoulder Score and Quick Disabilities of the Arm, Shoulder and Hand score. Post-operative measurements were made for active shoulder movements. Results Thirty-two patients were reviewed at a mean of 67 months following surgery. All patients demonstrated fatty infiltration on their pre-operative magnetic resonance imaging scan. Muscle atrophy was shown in 22 patients and 12 had tendinopathy. Multiple regression analysis showed no correlation between the Oxford Shoulder Score (p = 0.443), the Quick Disabilities of the Arm, Shoulder and Hand score (p = 0.419), forward flexion (p = 0.170), external rotation (p = 0.755) and any of the pre-operative independent variables. Discussion The degree of fatty infiltration, muscle atrophy and tendinopathy of the rotator cuff muscle on pre-operative magnetic resonance imaging scanning is not associated with functional outcome score or functional movement at medium-term follow-up following total shoulder replacement. Level of evidence IV

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