Role of surgery in the management and prognosis of limited-stage small cell carcinoma of the esophagus

2014 ◽  
Vol 28 (5) ◽  
pp. 476-482 ◽  
Author(s):  
M. R. Xie ◽  
S. B. Xu ◽  
X. H. Sun ◽  
L. Ke ◽  
X. Y. Mei ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Limited Stage

scholarly journals Use of Chemoradiotherapy as a Treatment Option for Patients with Limited-Stage Primary Small Cell Carcinoma of the Esophagus

2021 ◽  
Vol Volume 13 ◽  
pp. 613-623
Author(s):  
Kaikai Zhao ◽  
Zhaoqin Huang ◽  
Youjiao Si ◽  
Liangchao Sun ◽  
Jinming Yu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Treatment Option ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Limited Stage

scholarly journals Treatment Strategies and Prognostic Factors of Limited-Stage Primary Small Cell Carcinoma of the Esophagus

2017 ◽  
Vol 12 (12) ◽  
pp. 1834-1844 ◽  
Author(s):  
Lei Xu ◽  
Yin Li ◽  
Xianben Liu ◽  
Haibo Sun ◽  
Ruixiang Zhang ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Treatment Strategies ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Limited Stage

scholarly journals Small cell carcinoma of the esophagus

2007 ◽  
Vol 20 (3) ◽  
pp. 216-218
Author(s):  
Roberto Pelegrini Coral ◽  
Antonio Hartmann ◽  
Fabiane P. Mastalir ◽  
Eduardo T. Mastalir
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Life Quality ◽  
Esophageal Resection ◽  
Endoscopic Examination ◽  
Small Cell ◽  
Treatment Protocols ◽  
Carcinoma Of The Esophagus ◽  
And Behavior

BACKGROUND: Small cell carcinoma of the esophagus is a rare disease, characterized by aggressive progression, which is similar in appearance and behavior to its counterpart of the lung. It has a high incidence of metastatic disease at presentation and a poor prognosis. Treatment protocols are not well established because of the small number of cases and lack of large studies. CASE REPORT: 66 year-old woman, was admitted to the hospital with persistent dysphagia. Radiologic and endoscopic examination revealed an stenosing tumor in the lower third of the esophagus. The biopsy specimen was diagnosed as small cell carcinoma of the esophagus. The patient underwent an esophagectomy with esophagogastric anastomosis. CONCLUSION: The role of surgery remains controversial and the improvement of life quality is to be considered. Therapeutic approach is mainly esophageal resection.

Primary small cell carcinoma of the esophagus: Retropective analysis of the Veterans Affairs Cancer Registry.

2012 ◽  
Vol 30 (4_suppl) ◽  
pp. 32-32
Author(s):  
Mahmoud Abu Hazeem ◽  
Ramya Thota ◽  
Shanmuga Subbiah
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cancer Registry ◽  
Combined Modality Therapy ◽  
Small Cell ◽  
Extensive Disease ◽  
Carcinoma Of The Esophagus ◽  
Limited Stage ◽  
Combined Modality ◽  
Extensive Stage

32 Background: Small cell carcinoma (SCC) of the esophagus is a rare aggressive and rapidly fatal neoplasm, often diagnosed in late stages. Hence no prospective studies evaluating the most effective treatment strategies have been done. We aim to describe the clinicopathological features and treatment outcomes of this rare entity. Methods: Retrospective analysis of 49 patients diagnosed with SCC of the esophagus from 1995 to 2009 was done via the Veteran's Affairs Central Cancer Registry. Demographics, staging, treatment, and outcomes data was recorded. Staging was classified as limited (no distant metastasis) or extensive stage (metastatic disease). Results: Out of 10,540 patients with esophageal cancer, 49 were diagnosed with SCC (0.005%) and were mainly located in the middle and lower thirds of the esophagus (84%). Median age of diagnosis was 64.1 yrs (range: 26-90). 19 patients had limited disease, 26 patients had extensive disease and four patients who were not staged adequately were excluded. Patients received a variety of treatments (Table) with different survival outcomes. Limited stage SCC patients had a median survival of 6.3 mos with patients who received combined modality therapy showing a trend towards improved outcomes. Extensive stage patients who received no therapy had very poor outcomes compared to patients who received any therapy. Conclusions: SCC of esophagus should be considered a systemic disease and like pulmonary SCC, it is an aggressive tumor associated with a poor prognosis. Patient numbers are too low to draw definitive conclusions regarding choice of therapy. Extensive disease patients benefit from chemotherapy and combined modality therapy should be considered in limited stage disease. [Table: see text]

scholarly journals MET-04 A case of Brain Metastases with repeated bleeding from Esophageal carcinoma

2020 ◽  
Vol 2 (Supplement_3) ◽  
pp. ii19-ii19
Author(s):  
Masataka Mikai ◽  
Mitsuyoshi Abe ◽  
Yo watanabe ◽  
Chie Nakada ◽  
Yutaka Huchinoue ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Brain Metastases ◽  
Esophageal Carcinoma ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cerebral Hemorrhage ◽  
Small Cell ◽  
The Body ◽  
Metastatic Brain Tumor ◽  
Carcinoma Of The Esophagus

Abstract Brain metastases from esophageal cancer is rare and the incidence has been reported at approximately 5%. We report a case of brain metastases with repeated bleeding from Esophageal carcinoma. The case is a 76-year-old man. Three years ago he was diagnosed with small cell carcinoma of the esophagus by endoscopic biopsy. Metastasis was found only in the cervical lymph node, but the condition was stable by chemoradiotherapy and no metastases were found throughout the body before 1 month. He was admitted to the hospital because of a sudden convulsion, and CT scan revealed cerebral hemorrhage in the right frontal lobe. We performed conservative treatment, but rebleeding was observed from the same site repeatedly after 1 month and 2 months. Due to the influence of bleeding, it was difficult to distinguish cerebral hemorrhage from brain tumor by contrast MRI. After surgery, the cause of bleeding was diagnosed as metastatic brain tumor of esophageal small cell carcinoma. Postoperative radiation therapy was performed in another hospital, but rebleeding was observed 3 months after the operation. A reoperation was performed at another hospital, and a recurrence of metastatic brain tumor was diagnosed. In the case of highly malignant metastatic brain tumors, it was considered necessary to frequently follow the images.

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