scholarly journals Safety and efficacy of ertugliflozin in Asian patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy: VERTIS Asia

2019 ◽  
Vol 21 (6) ◽  
pp. 1474-1482 ◽  
Author(s):  
Linong Ji ◽  
Yanmei Liu ◽  
Heng Miao ◽  
Yongli Xie ◽  
Ming Yang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Safety And Efficacy ◽  
Asian Patients ◽  
Metformin Monotherapy

scholarly journals COMPARISON OF THE EFFECT OF DAPAGLIFLOZIN ON CONTRAST TO STANDARD THERAPY OF THE PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CONCOMITANT OBESITY, THEIR EFFECT ON LABORATORY AND ANTHROPOMETRIC PARAMETERS

2020 ◽  
Vol 73 (3) ◽  
pp. 457-461
Author(s):  
Taras I. Griadil ◽  
Ivan V. Chopey ◽  
Kristian O. Debreceni ◽  
Mykhaylo M. Hechko ◽  
Yaroslav O. Mykhalko ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Laboratory ◽  
Glycosylated Hemoglobin ◽  
Anthropometric Parameters ◽  
Metformin Monotherapy ◽  
Effect Of Glucose ◽  
Standard Treatment Regimen

The aim: Evaluate clinical and laboratory parameters of the patients with type 2 diabetes mellitus and concomitant obesity after a course of dapagliflozin treatment and compare with a standard treatment regimen. Materials and methods: Conducted a comprehensive clinical laboratory examination and measurement of the anthropometric parameters of the patients with type 2 diabetes mellitus and concomitant obesity, with subsequent statistical calculations. Results: The data obtained at different stages of the study revealed a statistically significant effect of glucose treatment and glycosylated hemoglobin (HbA1c). Since the 6th month of dapagliflozin treatment, we have shown a tendency to lose weight compared to baseline in this group of patients and controls. Conclusions: Type 2 diabetes mellitus and obesity significantly increase the risk of developing a number of complications. Complex control and effects on clinical laboratory and anthropometric parameters can statistically significantly influence the development of the complications, and in this context, dapaglifloflozin showed statistically better results than standard metformin monotherapy.

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