Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity‐related type 2 diabetes mellitus

2019 ◽  
Vol 21 (5) ◽  
pp. 1111-1120 ◽  
Author(s):  
Can Wang ◽  
Yao Xiao ◽  
Jue Wang ◽  
Ning Hou ◽  
Weiyi Cui ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Disease Progression ◽  
Rhesus Monkeys ◽  
Dynamic Changes

Does Insulin Use Worsen the Prognosis of COVID-19 Patients with Type 2 Diabetes Mellitus? A Current Update

2021 ◽  
Vol 18 ◽  
Author(s):  
Elvan Wiyarta ◽  
Wismandari Wisnu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Disease Progression ◽  
Grey Literature ◽  
Final Analysis ◽  
Eligibility Criteria ◽  
New Perspective ◽  
Insulin Use

Background: Insulin has recently received special attention concerning its use in COVID-19 patients. Although controversial, insulin can be able to worsen the prognosis of COVID-19 patients with Type 2 Diabetes Mellitus (T2DM) through an inflammatory pathway. This uncertain aspect brings a new perspective related to insulin use in this pandemic era. Objective: We tried to collect and analyze various studies related to this issue to provide a complete picture of the prognosis of insulin use in COVID-19 patients with T2DM. Methods: We comprehensively searched PubMed, Cochrane CENTRAL, Embase, EBSCO CINAHL, MEDLINE, and grey literature databases for studies investigating the effect of insulin on COVID-19 outcomes, including mortality, hospitalization, disease progression, other prognostic surrogates. Records were screened against the eligibility criteria. Result: 2556 articles were retrieved and were screened. A total of 8 studies were included in the final analysis. There are no studies with solid evidence supporting the effect of insulin treatment on the worsening of the prognosis of COVID-19 patients with T2DM. Although several studies have shown that insulin is associated with a poor prognosis, most studies have not considered confounders. This certainly makes it challenging to analyze the effects of insulin independently. Conclusion: We propose that COVID-19 patients with T2DM continue to receive insulin, but with careful observation of the risk of disease progression.

scholarly journals Defining Disease Progression and Drug Durability in Type 2 Diabetes Mellitus

2019 ◽  
Vol 15 (2) ◽  
pp. 67 ◽  
Author(s):  
Sanjay Kalra ◽  
Nor Azmi Kamaruddin ◽  
Jayanti Visvanathan ◽  
Ravi Santani ◽  
◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Disease Progression

Burden of liver disease progression in hospitalized patients with type 2 diabetes mellitus

2021 ◽  
Author(s):  
Vincent Mallet ◽  
Lucia Parlati ◽  
Alessandro Martinino ◽  
Juan Pablo Scarano Pereira ◽  
Carmen Navas Jimenez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Liver Disease ◽  
Disease Progression ◽  
Hospitalized Patients ◽  
Liver Disease Progression

1413-P: Uncovering the Disease Progression Profile of the Patients with Type 2 Diabetes Mellitus and Atrial Fibrillation

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1413-P
Author(s):  
ZEFANG TANG ◽  
JINGJING WANG ◽  
YUAN ZHANG ◽  
PENGWEI HU ◽  
JING MEI ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Atrial Fibrillation ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Disease Progression
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