Development of a cardiovascular diseases risk prediction model and tools for C hinese patients with type 2 diabetes mellitus: A population‐based retrospective cohort study

2017 ◽  
Vol 20 (2) ◽  
pp. 309-318 ◽  
Author(s):  
Eric Yuk Fai Wan ◽  
Daniel Yee Tak Fong ◽  
Colman Siu Cheung Fung ◽  
Esther Yee Tak Yu ◽  
Weng Yee Chin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Cardiovascular Diseases ◽  
Prediction Model ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Population Based

Clinically Confirmed Type 2 Diabetes Mellitus and Colorectal Cancer Risk: A Population-Based, Retrospective Cohort Study

2006 ◽  
Vol 101 (8) ◽  
pp. 1872-1879 ◽  
Author(s):  
Paul J. Limburg ◽  
Robert A. Vierkant ◽  
Zachary S. Fredericksen ◽  
Cynthia L. Leibson ◽  
Robert A. Rizza ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Colorectal Cancer ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Cancer Risk ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Population Based

scholarly journals Association between Depression, Antidepression Medications, and the Risk of Developing Type 2 Diabetes Mellitus: A Nationwide Population-Based Retrospective Cohort Study in Taiwan

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Yi-Jen Fang ◽  
Tien-Yuan Wu ◽  
Jung-Nien Lai ◽  
Cheng-Li Lin ◽  
Ni Tien ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Antidepressant Treatment ◽  
Population Based

The relationship between depression, antidepressant medications (ADMs), and the risk of subsequent type 2 diabetes mellitus (T2DM) development remains controversial. Thus, we investigated this aspect by a population-based retrospective cohort study using the Longitudinal Health Insurance Database 2000 available in Taiwan. This large, observational study included 46,201 patients with depression and a 1 : 1 age- and sex-matched nondepression cohort enrolled between January 1, 2000, and December 31, 2013, and the newly diagnosed T2DM incidence rates were determined. We estimated the effects of depression on T2DM and the cumulative incidence curves by Cox proportional regression hazard models and Kaplan-Meier methods, respectively. We found that 47.97% of the patients with depression did not receive ADM. Among patients with depression who received ADM, 29.71%, 6.29%, 0.05%, 9.65%, and 6.32% received selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), heterocyclic antidepressants, and other medications, respectively. Patients without ADM treatment had a 39% higher risk of developing T2DM. However, those who received ADM treatment had a significantly lower risk of T2DM development in every treatment category. Depressive disorder treated with ADMs, especially with long-term use, was associated with an 11–48% decrease in the risk of T2DM in all ADM groups; however, heterocyclic antidepressant treatment for shorter periods (<80 days) was not significantly associated with a decreased risk of T2DM. The incidence of T2DM in Taiwan was found to be associated with an a priori history of depression and was inversely correlated with ADM treatment.

Sign in / Sign up

Export Citation Format

Share Document