Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin (DA-1229)

Jaeseong Oh; Andrew HyoungJin Kim; SeungHwan Lee; Hyunjeong Cho; Yon Su Kim; Mi Young Bahng; Seo Hyun Yoon; Joo-Youn Cho; In-Jin Jang; Kyung-Sang Yu

doi:10.1111/dom.12813

Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin (DA-1229)

Diabetes Obesity and Metabolism ◽

10.1111/dom.12813 ◽

2016 ◽

Vol 19 (2) ◽

pp. 294-298 ◽

Cited By ~ 10

Author(s):

Jaeseong Oh ◽

Andrew HyoungJin Kim ◽

SeungHwan Lee ◽

Hyunjeong Cho ◽

Yon Su Kim ◽

...

Keyword(s):

Renal Impairment ◽

Dipeptidyl Peptidase ◽

Pharmacokinetics And Pharmacodynamics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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First-in-Human, Single-Ascending Dose and Food Effect Studies to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Cetagliptin, a Dipeptidyl Peptidase-4 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Clinical Drug Investigation ◽

10.1007/s40261-021-01088-5 ◽

2021 ◽

Author(s):

Lu Wang ◽

Jinmiao Lu ◽

Sufeng Zhou ◽

Yuqing Zhao ◽

Lijun Xie ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Food Effect ◽

Dipeptidyl Peptidase ◽

Pharmacokinetics And Pharmacodynamics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin*

Diabetes Obesity and Metabolism ◽

10.1111/j.1463-1326.2011.01458.x ◽

2011 ◽

Vol 13 (10) ◽

pp. 939-946 ◽

Cited By ~ 120

Author(s):

U. Graefe-Mody ◽

C. Friedrich ◽

A. Port ◽

A. Ring ◽

S. Retlich ◽

...

Keyword(s):

Renal Impairment ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Single and multiple dose pharmacokinetics and pharmacodynamics of omarigliptin, a novel, once-weekly dipeptidyl peptidase-4 inhibitor, in healthy Japanese men

Journal of Diabetes Investigation ◽

10.1111/jdi.12538 ◽

2016 ◽

Vol 8 (1) ◽

pp. 84-92 ◽

Cited By ~ 9

Author(s):

Saori Tsuchiya ◽

Evan Friedman ◽

Carol Addy ◽

Akira Wakana ◽

Daniel Tatosian ◽

...

Keyword(s):

Multiple Dose ◽

Dipeptidyl Peptidase ◽

Pharmacokinetics And Pharmacodynamics ◽

Japanese Men ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Multiple Dose Pharmacokinetics

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Treatment With the Dipeptidyl Peptidase-4 Inhibitor Linagliptin or Placebo Followed by Glimepiride in Patients With Type 2 Diabetes With Moderate to Severe Renal Impairment: A 52-Week, Randomized, Double-Blind Clinical Trial: Figure 1

Diabetes Care ◽

10.2337/dc14-1684 ◽

2015 ◽

Vol 38 (2) ◽

pp. e15-e17 ◽

Cited By ~ 27

Author(s):

Markku Laakso ◽

Julio Rosenstock ◽

Per-Henrik Groop ◽

Anthony H. Barnett ◽

Baptist Gallwitz ◽

...

Keyword(s):

Type 2 Diabetes ◽

Clinical Trial ◽

Renal Impairment ◽

Severe Renal Impairment ◽

Dipeptidyl Peptidase ◽

Double Blind ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Double Blind Clinical Trial

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Clinical Pharmacokinetics and Pharmacodynamics of Saxagliptin, a Dipeptidyl Peptidase-4 Inhibitor

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0421-4 ◽

2016 ◽

Vol 56 (1) ◽

pp. 11-24 ◽

Cited By ~ 12

Author(s):

David W. Boulton

Keyword(s):

Dipeptidyl Peptidase ◽

Pharmacokinetics And Pharmacodynamics ◽

Clinical Pharmacokinetics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Author response to letter from Snyder et al. regarding manuscript entitled ‘Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor, linagliptin’ by Graefe-Mody et al.

Diabetes Obesity and Metabolism ◽

10.1111/j.1463-1326.2012.01597.x ◽

2012 ◽

Vol 14 (7) ◽

pp. 671-672

Author(s):

U. Graefe-Mody ◽

C. Friedrich ◽

A. Port ◽

A. Ring ◽

S. Retlich ◽

...

Keyword(s):

Renal Impairment ◽

Dipeptidyl Peptidase ◽

Author Response ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2011.03937.x ◽

2011 ◽

Vol 72 (1) ◽

pp. 92-102 ◽

Cited By ~ 18

Author(s):

Vijay V. Upreti ◽

David W. Boulton ◽

Li Li ◽

Agatha Ching ◽

Hong Su ◽

...

Keyword(s):

Healthy Subjects ◽

Dipeptidyl Peptidase ◽

Pharmacokinetics And Pharmacodynamics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Safety, Pharmacokinetics, and Pharmacodynamics of a Dipeptidyl Peptidase‐4 Inhibitor: A Randomized, Double‐Blinded, Placebo‐Controlled Daily Administration of Fotagliptin Benzoate for 14 Days for Type 2 Diabetes Mellitus

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.895 ◽

2021 ◽

Author(s):

Min Wu ◽

Qian‐Qian Li ◽

Hong Zhang ◽

Xiao‐Xue Zhu ◽

Xiao‐Jiao Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Dipeptidyl Peptidase ◽

Daily Administration ◽

Pharmacokinetics And Pharmacodynamics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Double Blinded

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Reply to: Graefe-Mody U, Friedrich C, Port A et al. Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin. Diabetes Obes Metab 2011; 13: 939-946

Diabetes Obesity and Metabolism ◽

10.1111/j.1463-1326.2012.01588.x ◽

2012 ◽

Vol 14 (7) ◽

pp. 670-670

Author(s):

B. Snyder ◽

T. M. Polasek ◽

M. P. Doogue

Keyword(s):

Renal Impairment ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor

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Pharmacokinetics and Pharmacodynamics of Single Rising Intravenous Doses (0.5 mg–10 mg) and Determination of Absolute Bioavailability of the Dipeptidyl Peptidase-4 Inhibitor Linagliptin (BI 1356) in Healthy Male Subjects

Clinical Pharmacokinetics ◽

10.2165/11536620-000000000-00000 ◽

2010 ◽

Vol 49 (12) ◽

pp. 829-840 ◽

Cited By ~ 34

Author(s):

Silke Retlich ◽

Vincent Duval ◽

Arne Ring ◽

Alexander Staab ◽

Silke Hüttner ◽

...

Keyword(s):

Dipeptidyl Peptidase ◽

Absolute Bioavailability ◽

Healthy Male ◽

Pharmacokinetics And Pharmacodynamics ◽

Dipeptidyl Peptidase 4 ◽

Dipeptidyl Peptidase 4 Inhibitor ◽

Male Subjects

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