Preference in time of insulin injection in type 2 diabetic patients treated with once-daily long-acting insulin analog

2016 ◽  
Vol 18 (11) ◽  
pp. 1098-1099
Author(s):  
M. Takahara ◽  
T. Shiraiwa ◽  
N. Katakami ◽  
T.A. Matsuoka ◽  
I. Shimomura
Keyword(s):  
Insulin Injection ◽  
Insulin Analog ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Once Daily ◽  
Acting Insulin ◽  
Long Acting ◽  
Type 2 Diabetic

scholarly journals Insulin Injection Technique is Negatively Correlate to Short- and Long-run Glycemic Control in Type 2 Diabetic Patients with Long-Acting Insulin Analogue

2021 ◽  
Author(s):  
Yan Cheng ◽  
Qing-he Li ◽  
Fen-di Yi ◽  
Li-ping Chen ◽  
Lei Yuan ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Insulin Analogue ◽  
Insulin Injection ◽  
Injection Technique ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Acting Insulin ◽  
Long Run ◽  
Long Acting

Abstract Objective: To observe the effects of insulin injection technique (IT) on short- or long-run glycemic control in type 2 diabetic patients (T2D) with long-acting insulin analogue. Methods: This was a single-center, cross-over, observational and open-labled study. Patients with T2D receiving long-acting insulin analogue insulin were enrolled as inpatients. The study period lasting for 5 days including a 1-day screen period and 4-day continuous glucose monitoring (CGM) period. During CGM period, patients injected insulin themselves from day 1 to day 2, and patient’s insulin IT was given by two independent specialist nurses, with insulin injected by nurses from day 3 to day 4. The primary endpoint was the correlation between the insulin IT and the mean amplitude of glycemic excursion (MAGE). Results: A total of 60 diabetic inpatients were recruited and completed the study. The mean score of patients’ insulin IT of patients was lower than that of nurses (p<0.05). We observed that the MAGE value was significant different between the two injections period (P<0.05), and needle reuse and rotation of injection site were negatively correlated to MAGE and HbA1c values, respectively. Conclusion: Insulin IT was negatively correlation to short- or long-run glycemic control in T2D patients with long-acting insulin analogue therapy.

scholarly journals Increased Urine IgM and IgG2Levels, Indicating Decreased Glomerular Size Selectivity, Are Not Affected by Dalteparin Therapy in Patients with Type 2 Diabetes

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Ole Torffvit ◽  
Majid Kalani ◽  
Jan Apelqvist ◽  
Björn Eliasson ◽  
Jan W. Eriksson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Physiological Saline ◽  
Diabetic Patients ◽  
Size Selectivity ◽  
Type 2 Diabetic Patients ◽  
Once Daily ◽  
Urinary Levels ◽  
Glomerular Size ◽  
Type 2 Diabetic

Fifty-four type 2 diabetic patients with neuroischemic foot ulcers were randomised to treatment with 5000 IU of dalteparin, (n=28), or physiological saline, (n=26), once daily until ulcer healing or for a maximum of 6 months. Thirty-three patients had normo-, 15 micro-, and 6 macroalbuminuria. The urinary levels of IgM and IgG2were elevated in 47 and 50 patients, respectively. Elevated urinary levels of IgM and IgG2indicate decreased glomerular size selectivity. Urine IgM levels were associated with IGF-1/IGFBP-1 and IGFBP-1 levels. Dalteparin treatment increased urinary levels of glycosaminoglycans (P<0.001) and serum IGFBP-1 (P<0.05) while no significant effects were seen in any of the other studied parameters. In conclusion, dalteparin therapy in patients with type 2 diabetes had no effects on urinary levels of albumin, IgM, or IgG2despite significantly increased glycosaminoglycans in urine. Elevated urinary levels of IgM and IgG2might be more sensitive markers of renal disease than albuminuria in patients with type 2 diabetes and antihypertensive therapy.

scholarly journals Effects of Twice-Daily Injections of Premixed Insulin Analog on Glycemic Control in Type 2 Diabetic Patients

2010 ◽  
Vol 51 (6) ◽  
pp. 845 ◽  
Author(s):  
Hiroaki Shimizu ◽  
Tsuyoshi Monden ◽  
Mihoko Matsumura ◽  
Nozomi Domeki ◽  
Kikuo Kasai
Keyword(s):  
Glycemic Control ◽  
Insulin Analog ◽  
Diabetic Patients ◽  
Premixed Insulin ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic
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