Once-daily initiation of basal insulin as add-on to metformin: a 26-week, randomized, treat-to-target trial comparing insulin detemir with insulin glargine in patients with type 2 diabetes

L. Meneghini; J. Kesavadev; M. Demissie; A. Nazeri; P. Hollander

doi:10.1111/dom.12083

Once-daily initiation of basal insulin as add-on to metformin: a 26-week, randomized, treat-to-target trial comparing insulin detemir with insulin glargine in patients with type 2 diabetes

Diabetes Obesity and Metabolism ◽

10.1111/dom.12083 ◽

2013 ◽

Vol 15 (8) ◽

pp. 729-736 ◽

Cited By ~ 38

Author(s):

L. Meneghini ◽

J. Kesavadev ◽

M. Demissie ◽

A. Nazeri ◽

P. Hollander

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Basal Insulin ◽

Insulin Detemir ◽

Treat To Target ◽

Target Trial ◽

Once Daily

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A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs

Diabetes Care ◽

10.2337/dc09-2294 ◽

2010 ◽

Vol 33 (6) ◽

pp. 1176-1178 ◽

Cited By ~ 101

Author(s):

S. G. Swinnen ◽

M.-P. Dain ◽

R. Aronson ◽

M. Davies ◽

H. C. Gerstein ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Detemir ◽

Treat To Target ◽

Oral Glucose ◽

Target Trial ◽

Once Daily ◽

Glucose Lowering

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Rationale, Design, and Baseline Data of the Insulin Glargine (Lantus) Versus Insulin Detemir (Levemir) Treat-To-Target (L2T3) Study: A Multinational, Randomized Noninferiority Trial of Basal Insulin Initiation in Type 2 Diabetes

Diabetes Technology & Therapeutics ◽

10.1089/dia.2009.0044 ◽

2009 ◽

Vol 11 (11) ◽

pp. 739-743 ◽

Cited By ~ 13

Author(s):

Sanne G.H.A. Swinnen ◽

Frank J. Snoek ◽

Marie-Paule Dain ◽

J. Hans DeVries ◽

Joost B.L. Hoekstra ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Basal Insulin ◽

Insulin Detemir ◽

Baseline Data ◽

Treat To Target ◽

Insulin Initiation ◽

Noninferiority Trial

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A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes

Diabetologia ◽

10.1007/s00125-007-0911-x ◽

2008 ◽

Vol 51 (3) ◽

pp. 408-416 ◽

Cited By ~ 305

Author(s):

J. Rosenstock ◽

M. Davies ◽

P. D. Home ◽

J. Larsen ◽

C. Koenen ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Detemir ◽

Treat To Target ◽

Target Trial ◽

Glucose Lowering

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A 52-week, multinational, open-label, parallel-group, noninferiority, treat-to-target trial comparing insulin detemir with insulin glargine in a basal-bolus regimen with mealtime insulin aspart in patients with type 2 diabetes

Clinical Therapeutics ◽

10.1016/j.clinthera.2008.11.001 ◽

2008 ◽

Vol 30 (11) ◽

pp. 1976-1987 ◽

Cited By ~ 106

Author(s):

Priscilla Hollander ◽

John Cooper ◽

Jesper Bregnhøj ◽

Claus Bang Pedersen

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Detemir ◽

Treat To Target ◽

Target Trial ◽

Open Label ◽

Parallel Group ◽

Mealtime Insulin ◽

Basal Bolus

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Efficacy and safety of basal insulin glargine 12 and 24 weeks after initiation in persons with type 2 diabetes: A pooled analysis of data from treatment arms of 15 treat-to-target randomised controlled trials

Diabetes Research and Clinical Practice ◽

10.1016/j.diabres.2014.08.003 ◽

2014 ◽

Vol 106 (2) ◽

pp. 264-274 ◽

Cited By ~ 27

Author(s):

David R. Owens ◽

Louise Traylor ◽

Marie-Paule Dain ◽

Wolfgang Landgraf

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Basal Insulin ◽

Randomised Controlled Trials ◽

Pooled Analysis ◽

Treat To Target ◽

Controlled Trials ◽

Efficacy And Safety ◽

Randomised Controlled

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Glycaemic control and hypoglycaemia in people with type 2 diabetes switching from twice‐daily basal insulin to once‐daily insulin glargine 300 U/mL or insulin glargine 100 U/mL ( EDITION 1 and EDITION 2 subgroup analysis)

Diabetes Obesity and Metabolism ◽

10.1111/dom.13071 ◽

2017 ◽

Vol 20 (2) ◽

pp. 448-452 ◽

Cited By ~ 4

Author(s):

Ronan Roussel ◽

Michael C. d'Emden ◽

Miles Fisher ◽

F. Javier Ampudia‐Blasco ◽

Peter Stella ◽

...

Keyword(s):

Type 2 Diabetes ◽

Glycaemic Control ◽

Insulin Glargine ◽

Subgroup Analysis ◽

Basal Insulin ◽

Once Daily ◽

Daily Insulin

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Comment on: Bergenstal et al. A Randomized, Controlled Study of Once-Daily LY2605541, a Novel Long-Acting Basal Insulin, Versus Insulin Glargine in Basal Insulin-Treated Patients With Type 2 Diabetes. Diabetes Care 2012;35:2140-2147

Diabetes Care ◽

10.2337/dc13-0038 ◽

2013 ◽

Vol 36 (7) ◽

pp. e106-e106

Author(s):

P. D. Home

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Diabetes Care ◽

Basal Insulin ◽

Randomized Controlled Study ◽

Controlled Study ◽

Once Daily ◽

Randomized Controlled ◽

Long Acting

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Insulin degludec compared with insulin glargine in insulin‐naïve patients with type 2 diabetes: A 26‐week, randomized, controlled, P an‐ A sian, treat‐to‐target trial

Journal of Diabetes Investigation ◽

10.1111/jdi.12102 ◽

2013 ◽

Vol 4 (6) ◽

pp. 605-612 ◽

Cited By ~ 66

Author(s):

Yukiko Onishi ◽

Yasuhiko Iwamoto ◽

Soon Jib Yoo ◽

Per Clauson ◽

Søren C Tamer ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Degludec ◽

Treat To Target ◽

Target Trial ◽

Randomized Controlled

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The Efficacy and Safety of Insulin Degludec Given in Variable Once-Daily Dosing Intervals Compared With Insulin Glargine and Insulin Degludec Dosed at the Same Time Daily: A 26-week, randomized, open-label, parallel-group, treat-to-target trial in individuals with type 2 diabetes

Diabetes Care ◽

10.2337/dc12-1668 ◽

2013 ◽

Vol 36 (4) ◽

pp. 858-864 ◽

Cited By ~ 148

Author(s):

L. Meneghini ◽

S. L. Atkin ◽

S. C. L. Gough ◽

I. Raz ◽

L. Blonde ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Degludec ◽

Treat To Target ◽

Efficacy And Safety ◽

Target Trial ◽

Open Label ◽

Once Daily ◽

Parallel Group ◽

Dosing Intervals

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Insulin Degludec Versus Insulin Glargine in Insulin-Naive Patients With Type 2 Diabetes: A 1-year, randomized, treat-to-target trial (BEGIN Once Long)

Diabetes Care ◽

10.2337/dc12-1205 ◽

2012 ◽

Vol 35 (12) ◽

pp. 2464-2471 ◽

Cited By ~ 221

Author(s):

B. Zinman ◽

A. Philis-Tsimikas ◽

B. Cariou ◽

Y. Handelsman ◽

H. W. Rodbard ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Degludec ◽

Treat To Target ◽

Target Trial

Download Full-text