scholarly journals Developing a realist informed framework for cultural adaptation of lifestyle interventions for the prevention of type 2 diabetes in South Asian populations in Europe

2021 ◽  
Author(s):  
Emma M Davidson ◽  
Marta Krasuska ◽  
Anne Karen Jenum ◽  
Jason M.R. Gill ◽  
Erik Beune ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
D. R. Webb ◽  
K. Khunti ◽  
S. Chatterjee ◽  
J. Jarvis ◽  
M. J. Davies

Aims. Adipocytokines are implicated in the pathogenesis of type 2 diabetes and may represent identifiable precursors of metabolic disease within high-risk groups. We investigated adiponectin, leptin, and TNF-αand assessed the contribution of these molecules to insulin resistance in south Asians.Hypothesis. South Asians have adverse adipocytokine profiles which associate with an HOMA-derived insulin resistance phenotype.Methods. We measured adipocytokine concentrations in south Asians with newly diagnosed impaired glucose tolerance or Type 2 Diabetes Mellitus in a case-control study. 158 (48.5% males) volunteers aged 25–75 years with risk factors for diabetes but no known vascular or metabolic disease provided serum samples for ELISA and bioplex assays.Results. Total adiponectin concentration progressively decreased across the glucose spectrum in both sexes. A reciprocal trend in leptin concentration was observed only in south Asian men. Adiponectin but not leptin independently associated with HOMA-derived insulin resistance after logistic multivariate regression.Conclusion. Diasporic south Asian populations have an adverse adipocytokine profile which deteriorates further with glucose dysregulation. Insulin resistance is inversely associated with adiponectin independent of BMI and waist circumference in south Asians, implying that adipocytokine interplay contributes to the pathogenesis of metabolic disease in this group.


2015 ◽  
Vol 11 (3) ◽  
pp. 375-384 ◽  
Author(s):  
Pietro Amedeo Modesti ◽  
Giorgio Galanti ◽  
Piergiuseppe Cala’ ◽  
Maria Calabrese

2011 ◽  
Vol 28 (6) ◽  
pp. 673-680 ◽  
Author(s):  
S. D. Rees ◽  
M. Islam ◽  
M. Z. I. Hydrie ◽  
B. Chaudhary ◽  
S. Bellary ◽  
...  

Meta Gene ◽  
2020 ◽  
Vol 26 ◽  
pp. 100771
Author(s):  
Hina Batool ◽  
Nada Mushtaq ◽  
Sana Batool ◽  
Fariha Inayat Ullah ◽  
Arslan Hamid ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. e012783 ◽  
Author(s):  
Mirthe Muilwijk ◽  
Karien Stronks ◽  
Samera Azeem Qureshi ◽  
Erik Beune ◽  
Carlos Celis-Morales ◽  
...  

2021 ◽  
Author(s):  
Nithya Neelakantan ◽  
Su Hyun Park ◽  
Guo-Chong Chen ◽  
Rob M van Dam

Abstract Context The prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) is increasing in Asia and several countries are adopting preventive policies to reduce consumption of sugar-sweetened beverages (SSBs). However, evidence on the relation between SSB consumption and cardiometabolic health in Asian populations has not been summarized. Objective In this systematic review, the associations between consumption of SSBs and cardiometabolic outcomes, including obesity, T2DM, and CVD, are examined in Asian populations. Data sources The PubMed, Scopus, and Web of Science databases, and gray literature were searched up to October, 2020 to identify relevant articles. Data extraction Two investigators independently extracted data from included studies. Data analysis When sufficient studies were available, a random-effects meta-analysis was used to calculate the pooled estimates (expressed as risk ratio [RR] and 95% confidence interval [CI]). Heterogeneity was tested and quantified using the Cochrane Q test and I2 statistic, respectively. Results Of the 17 studies included, 8 provided results about measures of adiposity (3 on weight change, 4 on body mass index (BMI), 2 on percent body fat, and 1 on abdominal obesity), 6 reported results about T2DM, and 3 reported on different CVD outcomes. High SSB consumption was significantly associated with greater weight gain and with a higher risk of selected CVD outcomes as compared with low consumption. In the meta-analysis, high SSB consumption was associated with greater T2DM risk before (RR, 1.51; 95%CI, 1.15–1.98 for highest vs lowest category; I2 = 76%) and after (RR, 1.38; 95%CI, 1.09–1.73; I2 = 56%) adjustment for BMI. Conclusions These findings suggest that high SSB consumption is directly associated with weight gain, risk of T2DM, and, possibly, selected CVD outcomes in Asian populations. Public health strategies to reduce SSB consumption in Asian countries are warranted. Systematic Review Registration PROSPERO registration no. CRD42019129456.Keywords: adiposity. cardiovascular disease, Asia, sugar-sweetened beverages, type 2 diabetes.


2007 ◽  
Vol 286 ◽  
pp. 1-3

In a nutshellDietary advice for diabetics has included both reducing and increasing CHO.Some short term trials show improved glucose control from lower CHO, more fibre and lower GI foods. Light alcohol intake may provide some benefit. All these require further trials on their long term outcomes. And we should remember that, of all the lifestyle interventions in type 2 diabetes, the most effective appears to be exercise.


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