scholarly journals Depressive symptoms and cerebral microvascular disease in adults with Type 1 diabetes mellitus

2019 ◽  
Vol 36 (9) ◽  
pp. 1168-1175 ◽  
Author(s):  
K. A. Nunley ◽  
J. F. Karp ◽  
T. J. Orchard ◽  
T. Costacou ◽  
H. J. Aizenstein ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Depressive Symptoms ◽  
Type 1 Diabetes Mellitus ◽  
Microvascular Disease

Nephrolithiasis and Early-Onset Microvascular Disease in Type 1 Diabetes mellitus

Nephron ◽  
1994 ◽  
Vol 66 (3) ◽  
pp. 364-365
Author(s):  
Peter H. Winocour ◽  
Carlo Catalano ◽  
John S. Tapson
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Early Onset ◽  
Microvascular Disease

scholarly journals Optical Coherence Tomography Angiography in Type 1 Diabetes Mellitus. Report 4: Glycated Haemoglobin

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1537
Author(s):  
Carolina Bernal-Morales ◽  
Aníbal Alé-Chilet ◽  
Ruben Martín-Pinardel ◽  
Marina Barraso ◽  
Teresa Hernández ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Microvascular Disease ◽  
Glycated Haemoglobin ◽  
Optical Coherence ◽  
Patients At Risk ◽  
Hba1c Levels

The purpose of this study was to evaluate specifically the relationship between glycated haemoglobin (HbA1c) levels and retinal optical coherence tomography (OCT) and OCT angiography (OCTA) parameters in type 1 Diabetes Mellitus (DM). A total of 478 type 1 DM patients and 115 controls were included in a prospective OCTA trial (ClinicalTrials.gov NCT03422965). Subgroup analysis was performed for controls, no diabetic retinopathy (DM-no DR) and DR patients (DM-DR), and HbA1c levels. OCT and OCTA measurements were compared with HbA1c levels (current and previous 5 years). DM-no DR patients with HbA1c levels >7.5% showed lower VD than DM-DR and controls (20.16 vs. 20.22 vs. 20.71, p < 0.05), and showed a significant correlation between HbA1c levels and FAZc (p = 0.04), after adjusting for age, gender, signal strength index, axial length, and DM disease duration. DM-DR patients with HbA1c > 7.5% presented greater CRT than DM-no DR and controls (270.8 vs. 260 vs. 251.1, p < 0.05) and showed a significant correlation between HbA1c and CRT (p = 0.03). In conclusion, greater levels of HbA1c are associated with OCTA changes in DM-no DR patients, and with structural OCT changes in DM-DR patients. The combination of OCTA and OCT measurements and HbA1c levels may be helpful to identify patients at risk of progression to greater stages of the diabetic microvascular disease.

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