Positivity for islet cell autoantibodies in patients with monogenic diabetes is associated with later diabetes onset and higher HbA1clevel

2013 ◽  
Vol 31 (4) ◽  
pp. 466-471 ◽  
Author(s):  
J. Urbanová ◽  
B. Rypáčková ◽  
Z. Procházková ◽  
P. Kučera ◽  
M. Černá ◽  
...  
Keyword(s):  
Islet Cell ◽  
Monogenic Diabetes ◽  
Diabetes Onset ◽  
Islet Cell Autoantibodies

ISLET CELL AUTOANTIBODIES: WHICH METHOD?

The Lancet ◽  
1983 ◽  
Vol 321 (8322) ◽  
pp. 479-480 ◽  
Author(s):  
Hubert Kolb ◽  
Gabriele Krügener ◽  
F. Arnold Gries ◽  
Otto Bellmann ◽  
Anne Clark ◽  
...  
Keyword(s):  
Islet Cell ◽  
Islet Cell Autoantibodies

Islet Cell Autoantibodies

1996 ◽  
pp. 441-448
Author(s):  
William A. Hagopian ◽  
ke Lernmark
Keyword(s):  
Islet Cell ◽  
Islet Cell Autoantibodies

scholarly journals Validity of ICA 512 As in Combination with other ISLET Cell Autoantibodies for Prediction Studies in Type 1 Diabetes

1999 ◽  
Vol 45 (3) ◽  
pp. 439-439
Author(s):  
G Krochik ◽  
C A Mazza ◽  
M Papouchado ◽  
R Stumpo ◽  
S Valdéz ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Islet Cell Autoantibodies

Hyperthyroidism following primary hypothyroidism in association with polyendocrine autoimmunity

1985 ◽  
Vol 108 (4) ◽  
pp. 491-497 ◽  
Author(s):  
P. M. Bell ◽  
D. G. Sinnamon ◽  
P. P. A. Smyth ◽  
H. A. Drexhage ◽  
M. Haire ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Autoimmune Disease ◽  
Islet Cell ◽  
Primary Hypothyroidism ◽  
Strong Family History ◽  
Thyroglobulin Antibodies ◽  
Thyroid Stimulating Immunoglobulins ◽  
History Of ◽  
Islet Cell Autoantibodies

Abstract. A 37 year old male with a strong family history of autoimmune disease presented with typical symptoms of hyperthyroidism. He had exophthalmos but no goitre. Hyperthyroidism was confirmed by failure of 131I neck uptake to suppress after 7 days treatment with triiodothyronine. Six years previously a diagnosis of primary hypothyroidism has been made. At diagnosis of hyperthyroidism, thyroglobulin antibodies, thyroidal microsomal antibodies and thyroid stimulating immunoglobulins were detected. The absence of thyroid growth stimulating immunoglobulins and presence of immunoglobulins blockink TSH-induced growth may account for the absence of goitre throughout. HLA -B8, -B, -DR3 and -DR4 genotypes, low C4 complement cocentrations and islet cell autoantibodies were detected at the time of diagnosis and 1 year later diabetes mellitus developed.

scholarly journals An interesting case of young onset diabetes mellitus

2017 ◽  
Vol 5 (9) ◽  
pp. 4178
Author(s):  
Shipra Gulati ◽  
Tanvi Batra ◽  
Akshay A. Dhamne ◽  
Vijayashree S. Gokhale
Keyword(s):  
Islet Cell ◽  
Financial Constraints ◽  
Positive Family History ◽  
Islet Cell Antibodies ◽  
Interesting Case ◽  
Monogenic Diabetes ◽  
Family History Of Diabetes ◽  
Regular Treatment ◽  
Diabetic Ketosis ◽  
History Of

A 24 years old female, was admitted with symptoms of urinary tract infection. She was married and had bad obstetric history. She was known diabetic for 16 years of age and was on regular treatment with injection human insulin mixtard since the time of diagnosis, but had no episode of diabetic ketosis/ ketoacidosis. She had a positive family history of diabetes. She was further evaluated and was found to have normal C peptide levels and islet cell antibodies were found to be negative. Hence, the possibility of MODY (monogenic diabetes) was considered. Her genetic testing could not be done due to financial constraints. But a trial of sulfonylureas was given along with reduction in the dose of insulin to which she responded well and is presently well controlled.

Islet cell autoantibodies: a family story

1996 ◽  
Vol 135 (6) ◽  
pp. 643-644
Author(s):  
Edwin AM Gale
Keyword(s):  
Islet Cell ◽  
Islet Cell Autoantibodies

Time-Resolved Fluorescence Imaging of Islet Cell Autoantibodies

2006 ◽  
Vol 1079 (1) ◽  
pp. 226-228 ◽  
Author(s):  
P. VUORINEN ◽  
M. RULLI ◽  
A. KUUSISTO ◽  
S. SIMELL ◽  
T. SIMELL ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Islet Cell ◽  
Time Resolved Fluorescence ◽  
Time Resolved ◽  
Islet Cell Autoantibodies
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