The cost-effectiveness of the Dose Adjustment for Normal Eating (DAFNE) structured education programme: an update using the Sheffield Type 1 Diabetes Policy Model

2013 ◽  
Vol 30 (10) ◽  
pp. 1236-1244 ◽  
Author(s):  
J. Kruger ◽  
A. Brennan ◽  
P. Thokala ◽  
H. Basarir ◽  
R. Jacques ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cost Effectiveness ◽  
Dose Adjustment ◽  
Education Programme ◽  
Structured Education ◽  
Policy Model ◽  
The Cost ◽  
Diabetes Policy

The cost-effectiveness of the KIds in control of food structured education programme for adolescents with type 1 diabetes

2015 ◽  
Author(s):  
Hasan Basirir ◽  
Alan Brennan ◽  
Richard Jacques ◽  
Daniel Pollard ◽  
Katherine Stevens ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cost Effectiveness ◽  
Education Programme ◽  
Structured Education ◽  
The Cost

Assessing the cost-effectiveness of Type 1 diabetes interventions: the Sheffield Type 1 Diabetes Policy Model

2014 ◽  
Vol 31 (4) ◽  
pp. 477-486 ◽  
Author(s):  
P. Thokala ◽  
J. Kruger ◽  
A. Brennan ◽  
H. Basarir ◽  
A. Duenas ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cost Effectiveness ◽  
Policy Model ◽  
The Cost ◽  
Diabetes Policy ◽  
Diabetes Interventions

scholarly journals COST-EFFECTIVENESS OF STRUCTURED EDUCATION IN CHILDREN WITH TYPE-1 DIABETES MELLITUS

2016 ◽  
Vol 32 (4) ◽  
pp. 203-211 ◽  
Author(s):  
Hasan Basarir ◽  
Alan Brennan ◽  
Richard Jacques ◽  
Daniel Pollard ◽  
Katherine Stevens ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cost Effectiveness ◽  
Usual Care ◽  
Treatment Effect ◽  
Severe Hypoglycemia ◽  
Structured Education ◽  
Effect Duration ◽  
The Cost

Objectives: Kids in Control OF Food (KICk-OFF) is a 5-day structured education program for 11- to 16-year-olds with type 1 diabetes mellitus (T1DM) who are using multiple daily insulin injections. This study evaluates the cost-effectiveness of the KICk-OFF education program compared with the usual care using data from the KICk-OFF trial.Methods: The short-term within-trial analysis covers the 2-year postintervention period. Data on glycated hemoglobin (HbA1c), severe hypoglycemia, and diabetic ketoacidosis (DKA) were collected over a 2-year follow-up period. Sub-group analyses have been defined on the basis of baseline HbA1c being below 7.5 percent (58.5 mmol/mol) (low group), between 7.5 percent and 9.5 percent (80.3 mmol/mol) (medium group), and over 9.5 percent (high group). The long-term cost-effectiveness evaluation has been conducted by using The Sheffield Type 1 Diabetes Policy Model, which is a patient-level simulation model on T1DM. It includes long-term microvascular (retinopathy, neuropathy, and nephropathy) and macrovascular (myocardial infarction, stroke, revascularization, and angina) diabetes-related complications and acute adverse events (severe hypoglycemia and DKA).Results: The most favorable within-trial scenario for the KICk-OFF arm led to an incremental cost-effectiveness ratio (ICER) of £23,688 (base year 2009) with a cost-effectiveness probability of 41.3 percent. Simulating the long-term complications using the full cohort data, the mean ICER for the base case was £28,813 (base year 2011) and the probability of the KICk-OFF intervention being cost-effective at £20,000/QALY threshold was 42.6 percent, with considerable variation due to treatment effect duration. For the high HbA1c sub-group, the KICk-OFF arm was “dominant” (meaning it provided better health gains at lower costs than usual care) over the usual care arm in each scenario considered.Conclusions: For the whole study population, the cost-effectiveness of KICk-OFF depends on the assumption for treatment effect duration. For the high baseline HbA1c sub-group, KICk-OFF arm was estimated to be dominant over the usual care arm regardless of the assumption on the treatment effect duration.

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