Impact of sleep, neuroendocrine, and executive function on health‐related quality of life in young people with craniopharyngioma

2021 ◽  
Author(s):  
Kristin A Niel ◽  
Kimberly L Klages ◽  
Thomas E Merchant ◽  
Merrill S Wise ◽  
Donna Hancock ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Executive Function ◽  
Young People ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Self-administration of adrenaline for anaphylaxis during in-hospital food challenges improves health-related quality of life

2020 ◽  
pp. archdischild-2020-319906
Author(s):  
Sarah Burrell ◽  
Nandinee Patel ◽  
Marta Vazquez-Ortiz ◽  
Dianne E. Campbell ◽  
Audrey DunnGalvin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young People ◽  
Self Efficacy ◽  
Food Challenge ◽  
Health Related Quality ◽  
Self Administration ◽  
Related Quality ◽  
Health Related ◽  
The Impact

ObjectiveTo assess the impact of anaphylaxis on health-related quality of life (HRQL) and self-efficacy in food-allergic patients undergoing in-hospital food challenge.DesignSecondary analysis of a randomised controlled trial.SettingSpecialist allergy centre.PatientsPeanut-allergic young people aged 8–16 years.InterventionsDouble-blind, placebo-controlled food challenge to peanut, with HRQL and self-efficacy assessed using validated questionnaire, approximately 2 weeks prior to and 2 weeks after challenge. Where possible, anaphylaxis was treated with self-injected adrenaline (epinephrine).Main outcome measuresChange in HRQL and self-efficacy.Results56 participants had reactions at food challenge, of whom 16 (29%) had anaphylaxis. Overall, there was an improvement in HRQL (mean 2.6 points (95% CI 0.3 to 4.8); p=0.030) and self-efficacy (mean 4.1 points (95% CI 2.4 to 5.9); p<0.0001), independent of whether anaphylaxis occurred. Parents also reported improved HRQL (mean 10.3 points (95% CI 5.9 to 14.7); p<0.0001). We found evidence of discordance between the improvement in HRQL and self-efficacy as reported by young people and that perceived by parents in their child.ConclusionsAnaphylaxis at food challenge, followed by self-administration of injected adrenaline, was associated with an increase in HRQL and self-efficacy in young people with peanut allergy. We found no evidence that the occurrence of anaphylaxis had a detrimental effect. Young people should be encouraged to self-administer adrenaline using their autoinjector device to treat anaphylaxis at in-hospital challenge.Trial registration numberNCT02149719

scholarly journals Parent reported health related quality of life (HRQoL) and behaviour in young people with epilepsy before and two years after epilepsy surgery

Seizure ◽  
2020 ◽  
Vol 74 ◽  
pp. 1-7 ◽  
Author(s):  
Colin Reilly ◽  
Tove Hallböök ◽  
Gerd Viggedal ◽  
Bertil Rydenhag ◽  
Paul Uvebrant ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young People ◽  
Epilepsy Surgery ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Reported Health
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