scholarly journals Brain activation patterns underlying upper limb bilateral motor coordination in unilateral cerebral palsy: an fNIRS study

2020 ◽  
Vol 62 (5) ◽  
pp. 625-632 ◽  
Author(s):  
Ana Carolina de Campos ◽  
Theresa Sukal‐Moulton ◽  
Theodore Huppert ◽  
Katharine Alter ◽  
Diane L Damiano
Keyword(s):  
Cerebral Palsy ◽  
Upper Limb ◽  
Motor Coordination ◽  
Brain Activation ◽  
Activation Patterns ◽  
Unilateral Cerebral Palsy

scholarly journals Upper limb impairments, process skills, and outcome in children with unilateral cerebral palsy

2019 ◽  
Vol 61 (9) ◽  
pp. 1080-1086 ◽  
Author(s):  
Remo N Russo ◽  
Pawel P Skuza ◽  
Myriam Sandelance ◽  
Peter Flett
Keyword(s):  
Cerebral Palsy ◽  
Upper Limb ◽  
Process Skills ◽  
Unilateral Cerebral Palsy

scholarly journals Transcranial Direct Current Stimulation (tDCS) in Unilateral Cerebral Palsy: A Pilot Study of Motor Effect

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Emanuela Inguaggiato ◽  
Nadia Bolognini ◽  
Simona Fiori ◽  
Giovanni Cioni
Keyword(s):  
Cerebral Palsy ◽  
Pilot Study ◽  
Upper Limb ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Motor Cortex ◽  
Controlled Study ◽  
Anodal Tdcs ◽  
Direct Current Stimulation ◽  
Unilateral Cerebral Palsy

Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the first time, the immediate effects, and their short-term persistence, of a single application of anodal tDCS on chronic upper limb motor disorders in children and young individuals with Unilateral Cerebral Palsy (UCP). To this aim, in a crossover sham-controlled study, eight subjects aged 10-28 years with UCP underwent two sessions of active and sham tDCS. Anodal tDCS (1.5 mA, 20 min) was delivered over the primary motor cortex (M1) of the ipsilesional hemisphere. Results showed, only following the active stimulation, an immediate improvement in unimanual gross motor dexterity of hemiplegic, but not of nonhemiplegic, hand in Box and Block test (BBT). Such improvement remained stable for at least 90 minutes. Performance of both hands in Hand Grip Strength test was not modified by anodal tDCS. Improvement in BBT was unrelated to participants’ age or lesion size, as revealed by MRI data analysis. No serious adverse effects occurred after tDCS; some mild and transient side effects (e.g., headache, tingling, and itchiness) were reported in a limited number of cases. This study provides an innovative contribution to scientific literature on the efficacy and safety of anodal tDCS in UCP. This trial is registered with NCT03137940.

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