scholarly journals Risk factors for perinatal arterial ischaemic stroke: a large case–control study

2019 ◽  
Vol 62 (4) ◽  
pp. 513-520 ◽  
Author(s):  
Anna‐Lisa Sorg ◽  
Rüdiger Kries ◽  
Mathias Klemme ◽  
Lucia Gerstl ◽  
Raphael Weinberger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Case Control Study ◽  
Case Control ◽  
Arterial Ischaemic Stroke ◽  
Control Study ◽  
Large Case

Risk factors for perinatal arterial ischaemic stroke in full-term infants: a case-control study

2012 ◽  
Vol 97 (6) ◽  
pp. F411-F416 ◽  
Author(s):  
Johanna C Harteman ◽  
Floris Groenendaal ◽  
Anneke Kwee ◽  
Paco MJ Welsing ◽  
Manon JNL Benders ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Case Control Study ◽  
Case Control ◽  
Full Term ◽  
Term Infants ◽  
Arterial Ischaemic Stroke ◽  
Control Study

Risk factors associated with perinatal arterial ischaemic stroke: a case-control study

2015 ◽  
Vol 357 ◽  
pp. e440-e441
Author(s):  
D. Munoz ◽  
M. Troncoso ◽  
M. Hidalgo ◽  
S. Lara ◽  
P. Parra ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Case Control Study ◽  
Case Control ◽  
Factors Associated ◽  
Arterial Ischaemic Stroke ◽  
Control Study

scholarly journals Association between excessive premature atrial complexes and cryptogenic stroke: results of a case–control study

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e029164 ◽  
Author(s):  
Jithin K Sajeev ◽  
Anoop N Koshy ◽  
Helen Dewey ◽  
Jonathan M Kalman ◽  
Kevin Rajakariar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Case Control Study ◽  
Cryptogenic Stroke ◽  
Case Control ◽  
Vascular Risk Factors ◽  
Control Group ◽  
Prior History ◽  
Vascular Risk ◽  
Control Study

ObjectiveRecent anticoagulation trials in all-comer cryptogenic stroke patients have yielded equivocal results, reinvigorating the focus on identifying reproducible markers of an atrial myopathy. We investigated the role of excessive premature atrial complexes (PACs) in ischaemic stroke, including cryptogenic stroke and its association with vascular risk factors.Methods and resultsA case–control study was conducted utilising a multicentre institutional stroke database to compare 461 patients with an ischaemic stroke or transient ischaemic attack (TIA) with a control group consisting of age matched patients without prior history of ischaemic stroke/TIA. All patients underwent 24-hour Holter monitoring during the study period and atrial fibrillation was excluded. An excessive PAC burden, defined as ≥200 PACs/24 hours, was present in 25.6% and 14.7% (p<0.01), of stroke/TIA and control patients, respectively. On multivariate regression, excessive PACs (OR 1.97; 95% CI 1.29 to 3.02; p<0.01), smoking (OR 1.58; 95% CI 1.06 to 2.36; p<0.05) and hypertension (OR 1.53; 95% CI 1.07 to 2.17; p<0.05) were independently associated with ischaemic stroke/TIA. Excessive PACs remained the strongest independent risk factor for the cryptogenic stroke subtype (OR 1.95; 95% CI 1.16 to 3.28; p<0.05). Vascular risk factors that promote atrial remodelling, increasing age (≥75 years, OR 3.64; 95% CI 2.08 to 6.36; p<0.01) and hypertension (OR 1.54; 95% CI 1.01 to 2.34; p<0.05) were independently associated with excessive PACs.ConclusionsExcessive PACs are independently associated with cryptogenic stroke and may be a reproducible marker of atrial myopathy. Prospective studies assessing their utility in guiding stroke prevention strategies may be warranted.

scholarly journals Incidence and risk factors for gallstones in patients with inflammatory bowel disease: A large case-control study

Hepatology ◽  
2007 ◽  
Vol 45 (5) ◽  
pp. 1267-1274 ◽  
Author(s):  
Fabrizio Parente ◽  
Luca Pastore ◽  
Stefano Bargiggia ◽  
Claudia Cucino ◽  
Salvatore Greco ◽  
...  
Keyword(s):  
Risk Factors ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Case Control Study ◽  
Case Control ◽  
Inflammatory Bowel ◽  
Control Study ◽  
Large Case

scholarly journals Additive interaction between potentially modifiable risk factors and ethnicity among individuals in the Han, Tujia and Miao populations with first-ever ischaemic stroke

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Na Zhang ◽  
Xinrui Wu ◽  
Mengyuan Tian ◽  
Xiaolei Wang ◽  
Jian Ding ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischaemic Stroke ◽  
Ethnic Minorities ◽  
Case Control Study ◽  
Case Control ◽  
Moderate Intensity ◽  
Modifiable Risk Factors ◽  
Additive Interaction ◽  
Han Population ◽  
Control Study

Abstract Background As a country with one-fifth of the global population, China has experienced explosive growth in ischaemic stroke (IS) burden with significant ethnic and geographic disparities. The aim of this study was to examine the differences in potentially modifiable risk factors for ischaemic stroke among the Han population and two ethnic minorities (Tujia and Miao). Methods A case-control study was conducted with 324 cases of first-ever ischaemic stroke from the hospitals of the Xiangxi Tujia and Miao Autonomous Prefecture and 394 controls from communities covering the same area between May 1, 2018, and April 30, 2019. Structured questionnaires were administered, and physical examinations were performed in the same manner for cases and controls. Univariate and multivariate logistic regression analyses with adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were used to examine the association between risk factors and ischaemic stroke. An additive model was used to study the interaction between the modifiable risk factors and ethnicity with R software. Results Higher high-sensitivity C-reactive protein levels (OR 50.54, 95%CI 29.76–85.85), higher monthly family income (4.18, 2.40–7.28), increased frequency of hot pot consumption (2.90, 1.21–6.93), diabetes mellitus (2.62, 1.48–4.62), a higher apolipoprotein (Apo)B/ApoA1 ratio (2.60, 1.39–4.85), hypertension (2.52, 1.45–4.40) and moderate-intensity physical activity (0.50, 0.28–0.89) were associated with ischaemic stroke. There was an additive interaction between the ApoB/ApoA1 ratio and ethnicity in the Tujia and Miao populations with first-ever ischaemic stroke (the relative excess risk due to the interaction was 5.75, 95% CI 0.58 ~ 10.92; the attributable proportion due to the interaction was 0.65, 95% CI 0.38 ~ 0.91; the synergy index was 3.66, 95% CI 1.35 ~ 9.93). Conclusions This is the first case-control study examining modifiable risk factors for ischaemic stroke among the Han population and two ethnic minorities (Tujia and Miao) in China. Some differences were observed in the impact of risk factors among these ethnic groups. Our results may help interpret health-related data, including surveillance and research, when developing strategies for stroke prevention.

scholarly journals Risk factors for ambulatory urinary tract infections caused by high-MIC fluoroquinolone-susceptibleEscherichia coliin women: results from a large case–control study

2015 ◽  
Vol 70 (5) ◽  
pp. 1547-1551 ◽  
Author(s):  
Pinyo Rattanaumpawan ◽  
Irving Nachamkin ◽  
Warren B. Bilker ◽  
Jason A. Roy ◽  
Joshua P. Metlay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Case Control Study ◽  
Case Control ◽  
Tract Infections ◽  
Control Study ◽  
Large Case

Risk factors for esophageal adenocarcinoma: A case-control study

2001 ◽  
Vol 120 (5) ◽  
pp. A442-A442
Author(s):  
B AVIDAN ◽  
A SONNENBERG ◽  
T SCHNELL ◽  
G CHEJFEC ◽  
A METZ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Adenocarcinoma ◽  
Case Control Study ◽  
Case Control ◽  
Control Study
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