Optical coherence tomography and magnetic resonance imaging visual pathway evaluation in Wolfram syndrome

2018 ◽  
Vol 61 (3) ◽  
pp. 359-365 ◽  
Author(s):  
Agnieszka Zmyslowska ◽  
Arleta Waszczykowska ◽  
Dobromila Baranska ◽  
Konrad Stawiski ◽  
Maciej Borowiec ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optical Coherence Tomography ◽  
Magnetic Resonance ◽  
Wolfram Syndrome ◽  
Visual Pathway ◽  
Optical Coherence ◽  
Resonance Imaging

scholarly journals Imaging the Visual Pathway in Neuromyelitis Optica

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Caspar F. Pfueller ◽  
Friedemann Paul
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optical Coherence Tomography ◽  
Magnetic Resonance ◽  
Neuromyelitis Optica ◽  
Current Knowledge ◽  
Visual Pathway ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

The focus of this paper is to summarize the current knowledge on visual pathway damage in neuromyelitis optica (NMO) assessed by magnetic resonance imaging (MRI) and optical coherence tomography (OCT).

scholarly journals Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

2012 ◽  
Vol 37 (5) ◽  
pp. 872 ◽  
Author(s):  
Jason M. Tucker-Schwartz ◽  
Tu Hong ◽  
Daniel C. Colvin ◽  
Yaqiong Xu ◽  
Melissa C. Skala
Keyword(s):  
Magnetic Resonance Imaging ◽  
Carbon Nanotubes ◽  
Optical Coherence Tomography ◽  
Magnetic Resonance ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Dual Modality

scholarly journals Coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of MINOCA in Women

Circulation ◽  
2020 ◽  
Author(s):  
Harmony R. Reynolds ◽  
Akiko Maehara ◽  
Raymond Y. Kwong ◽  
Tara Sedlak ◽  
Jacqueline Saw ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optical Coherence Tomography ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Cardiac Magnetic Resonance Imaging ◽  
Plaque Rupture ◽  
Cine Imaging ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Imaging Results

Background: Myocardial infarction with non-obstructive coronary arteries (MINOCA) occurs in 6-15% of MI and disproportionately affects women. Scientific statements recommend multi-modality imaging in MINOCA to define the underlying cause. We performed coronary optical coherence tomography (OCT) and cardiac magnetic resonance imaging (CMR) to assess mechanisms of MINOCA. Methods: In this prospective, multicenter, international, observational study, we enrolled women with a clinical diagnosis of MI. If invasive coronary angiography revealed <50% stenosis in all major arteries, multi-vessel OCT was performed, followed by CMR (cine imaging, late gadolinium enhancement, and T2-weighted imaging and/or T1 mapping). Angiography, OCT, and CMR were evaluated at blinded, independent core laboratories. Culprit lesions identified by OCT were classified as definite or possible. The CMR core laboratory identified ischemia-related and non-ischemic myocardial injury. Imaging results were combined to determine the mechanism of MINOCA, when possible. Results: Among 301 women enrolled at 16 sites, 170 were diagnosed with MINOCA, of whom 145 had adequate OCT image quality for analysis; 116 of these underwent CMR. A definite or possible culprit lesion was identified by OCT in 46.2% (67/145) of participants, most commonly plaque rupture, intra-plaque cavity or layered plaque. CMR was abnormal in 74.1% (86/116) of participants. An ischemic pattern of CMR abnormalities (infarction or myocardial edema in a coronary territory) was present in 53.4% of participants undergoing CMR (62/116). A non-ischemic pattern of CMR abnormalities (myocarditis, takotsubo syndrome or non-ischemic cardiomyopathy) was present in 20.7% (24/116). A cause of MINOCA was identified in 84.5% of the women with multi-modality imaging (98/116), higher than with OCT alone (p<0.001) or CMR alone (p=0.001). An ischemic etiology was identified in 63.8% of women with MINOCA (74/116), a non-ischemic etiology was identified in 20.7% (24/116), and no mechanism was identified in 15.5% (18/116). Conclusions: Multi-modality imaging with coronary OCT and CMR identified potential mechanisms in 84.5% of women with a diagnosis of MINOCA, three-quarters of which were ischemic and one-quarter of which were non-ischemic, alternate diagnoses to MI. Identification of the etiology of MINOCA is feasible and has the potential to guide medical therapy for secondary prevention. Clinical Trial Registration: URL: https://clinicaltrials.gov Unique Identifier: NCT02905357

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