scholarly journals Children with neurodevelopmental disorders and disabilities: a population-based study of healthcare service utilization using administrative data

2017 ◽  
Vol 59 (12) ◽  
pp. 1284-1290 ◽  
Author(s):  
Rubab G Arim ◽  
Anton R Miller ◽  
Anne Guèvremont ◽  
Lucyna M Lach ◽  
Jamie C Brehaut ◽  
...  
Keyword(s):  
Service Utilization ◽  
Administrative Data ◽  
Neurodevelopmental Disorders ◽  
Healthcare Service ◽  
Population Based ◽  
Population Based Study

scholarly journals Healthcare Service Utilization for Practicing Physicians: A Population-Based Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0130690 ◽  
Author(s):  
Yu-Lung Chiu ◽  
Senyong Kao ◽  
Herng-Ching Lin ◽  
Ming-Chieh Tsai ◽  
Cha-Ze Lee
Keyword(s):  
Service Utilization ◽  
Healthcare Service ◽  
Population Based ◽  
Population Based Study ◽  
Practicing Physicians

scholarly journals Healthcare Service Utilization by Patients with Obstructive Sleep Apnea: A Population-Based Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0137459 ◽  
Author(s):  
Li-Ting Kao ◽  
Hsin-Chien Lee ◽  
Herng-Ching Lin ◽  
Ming-Chieh Tsai ◽  
Shiu-Dong Chung
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Service Utilization ◽  
Healthcare Service ◽  
Population Based ◽  
Population Based Study ◽  
Obstructive Sleep

scholarly journals Prediction of in-hospital mortality after pancreatic resection in pancreatic cancer patients: A boosting approach via a population-based study using health administrative data

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0178757 ◽  
Author(s):  
Jose F. Velez-Serrano ◽  
Daniel Velez-Serrano ◽  
Valentin Hernandez-Barrera ◽  
Rodrigo Jimenez-Garcia ◽  
Ana Lopez de Andres ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Hospital Mortality ◽  
Cancer Patients ◽  
Administrative Data ◽  
Pancreatic Resection ◽  
Population Based ◽  
Population Based Study ◽  
Health Administrative Data

Validity of medico-administrative data related to amyotrophic lateral sclerosis in France: A population-based study

2016 ◽  
Vol 18 (1-2) ◽  
pp. 24-31 ◽  
Author(s):  
Rosario Vasta ◽  
Farid Boumédiene ◽  
Philippe Couratier ◽  
Marie Nicol ◽  
Alessandra Nicoletti ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Administrative Data ◽  
Population Based ◽  
Population Based Study ◽  
Lateral Sclerosis

scholarly journals In-Utero SSRI and SNRI Exposure and the Risk of Neurodevelopmental Disorders in Children: A Population-Based Retrospective Cohort Study Utilizing Linked Administrative Data

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Deepa Singal ◽  
Dan Chateau ◽  
Matthew Dahl ◽  
Shelley Derksen ◽  
Chelsea Ruth ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Anxiety Disorder ◽  
Disease Severity ◽  
Administrative Data ◽  
Neurodevelopmental Disorders ◽  
Population Based ◽  
In Utero ◽  
Autism Spectrum ◽  
Hazard Ratio ◽  
Spectrum Disorder

IntroductionMany studies demonstrating an association between in utero exposure to serotonergic antidepressants and higher risk of neurodevelopmental disorders in children are confounded by history of maternal depression and disease severity. We conducted a population-based analysis of women diagnosed with mood/anxiety disorder, a patient population for whom pharmacotherapy is clearly indicated. Objectives and ApproachUsing linked population-based administrative data, we identified all mother-newborn pairs in Manitoba (born 1996 to 2009, with follow-up through 2014). High dimensional propensity scores and inverse probability treatment weighting were used to address confounding by indication and disease severity. The final trimmed cohort consisted of mothers who were diagnosed with a mood/anxiety disorder from 90 days prior to conception until delivery (n=4995). Cox Proportional Hazard Regression models were used to estimate risk of Autism Spectrum Disorder, epilepsy and attention deficit hyperactivity disorder (ADHD) in offspring. In addition to clinical data, we used novel education data to define outcomes in children. ResultsAmong the cohort of mothers diagnosed with a mood/anxiety disorder during pregnancy or up to 90 days before, 16.8% received at least two dispensations of an SSRI or SNRI during pregnancy. We did not observe an association between use of SSRIs/SNRIs during pregnancy and increased risk of Autism Spectrum Disorder (hazard ratio 0.92; 95% CI 0.42 to 2.03), epilepsy (hazard ratio 1.21; 95% CI 0.48 to 3.05), or ADHD (hazard ratio 1.13, 95% CI 0.78 to 1.64) among offspring. Conclusion/ImplicationsIn the absence of randomized control trials, large observation studies using sophisticated data analysis are the gold standard of evidence to help patients and clinicians making the decision to continue antidepressant use during pregnancy. Results of this study reassure women for whom the medication is clinically indicated.

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