Objective measurements of gaze behaviour as a method to assess non-speaking children with severe motor impairments

2015 ◽  
Vol 57 ◽  
pp. 14-14
Keyword(s):  
Motor Impairments ◽  
Objective Measurements ◽  
Severe Motor ◽  
Gaze Behaviour

scholarly journals Infrared thermography as an access pathway for individuals with severe motor impairments

2021 ◽  
Author(s):  
Negar Memarian ◽  
Anastasios Venetsanopoulos ◽  
Tom Chau
Keyword(s):  
Infrared Thermography ◽  
Motor Impairments ◽  
Severe Motor ◽  
Access Pathway

Infrared thermography as an access pathway for individuals with severe motor impairments

Nascent Access Technologies for Individuals with Severe Motor Impairments

2013 ◽  
pp. 720-739
Author(s):  
Sarah Power ◽  
Saba Moghimi ◽  
Brian Nhan ◽  
Tom Chau
Keyword(s):  
Near Infrared ◽  
Scientific Evidence ◽  
Severe Disabilities ◽  
Motor Impairments ◽  
Temperature Changes ◽  
Severe Motor ◽  
The Face ◽  
Physical Access ◽  
Number Of Individuals ◽  
The Brain

As the number of individuals without physical access to communication or environmental interaction escalates, there are increasing efforts to uncover novel and unconventional access pathways. In this chapter, we introduce three emerging access technologies for individuals with severe disabilities: near-infrared spectroscopy, electroencephalographic measurement of visually-evoked potentials and infrared thermographic imaging of the face. The first two technologies harness activity directly from the brain while the third exploits spontaneous temperature changes in the face. For each technology, we discuss the physiological underpinnings, the requisite instrumentation, the scientific evidence to date and the future outlook.

scholarly journals Assisted Movement With Enhanced Sensation (AMES): Coupling Motor and Sensory to Remediate Motor Deficits in Chronic Stroke Patients

2008 ◽  
Vol 23 (1) ◽  
pp. 67-77 ◽  
Author(s):  
Paul Cordo ◽  
Helmi Lutsep ◽  
Linda Cordo ◽  
W. Geoffrey Wright ◽  
Timothy Cacciatore ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Motor Deficits ◽  
Motor Impairments ◽  
Joint Rotation ◽  
Motor Disability ◽  
Stroke Impact Scale ◽  
Impact Scale ◽  
Severe Motor ◽  
The Subject ◽  
Flexion And Extension

Background. Conventional methods of rehabilitation in patients with chronic, severe motor impairments after stroke usually do not lessen paresis. Objective. A novel therapeutic approach (assisted movement with enhanced sensation [AMES]) was employed in a medical device phase I clinical trial to reduce paresis and spasticity and, thereby, to improve motor function. Methods. Twenty subjects more than 1 year poststroke with severe motor disability of the upper or lower extremity were studied. A robotic device cycled the ankle or the wrist and fingers at 5°/s through ±17.5° in flexion and extension while the subject assisted this motion. Feedback of the subject's active torque was displayed on a monitor. Simultaneously, 2 vibrators applied a 60 pps stimulus to the tendons of the lengthening muscles, alternating from flexors to extensors as the joint rotation reversed from extension to flexion, respectively. Subjects treated themselves at home for 30 min/day for 6 months. Every other day prior to treatment, the therapy device performed automated tests of strength and joint positioning. Functional testing was performed prior to enrollment, immediately after completing the protocol, and 6 months later. Functional tests included gait and weight distribution (lower extremity subjects only) and the Stroke Impact Scale. Results. Most subjects improved on most tests, and gains were sustained for 6 months in most subjects. No safety problems arose. Conclusion. The AMES strategy appears safe and possibly effective in patients with severe chronic impairments. The mechanism underlying these gains is likely to be multifactorial.

scholarly journals Tendon and Motor Phenotypes in the Crtap-/- Mouse Model of Recessive Osteogenesis Imperfecta

2020 ◽  
Author(s):  
Matthew W. Grol ◽  
Nele A. Haelterman ◽  
Joohyun Lim ◽  
Elda M. Munivez ◽  
Marilyn Archer ◽  
...  
Keyword(s):  
Mouse Model ◽  
Osteogenesis Imperfecta ◽  
Bone Fragility ◽  
Joint Hypermobility ◽  
Motor Deficits ◽  
Motor Impairments ◽  
Matrix Gene ◽  
Severe Motor ◽  
Cross Links ◽  
Immature Cells

ABSTRACTOsteogenesis imperfecta (OI) is characterized by short stature, skeletal deformities, low bone mass with bone fragility, and motor deficits. A subset of OI patients also present with joint hypermobility; however, the role of tendon/ligament dysfunction in OI pathogenesis is largely unknown. Using the Crtap-/- mouse model of severe, recessive OI, we found that mutant Achilles tendons and patellar ligaments were thinner with increased collagen cross-links and reduced collagen fibril size at 1- and 4-months compared to wildtype. Patellar ligaments from Crtap-/- mice also had fewer progenitors with a concomitant increase in immature cells. RNA-seq analysis of Achilles tendons and patellar ligaments from 1-month Crtap-/- mice revealed dysregulation in matrix gene expression concomitant with predicted alterations in TGF-β, inflammatory, and metabolic signaling. Finally, a series of behavioral tests revealed severe motor impairments and reduced grip strength in 4-month Crtap-/- mice – a phenotype that correlates with the tendon/ligament pathology.

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